Body constitution in persons with diabetes mellitus from a perspective of Chinese medicine

2018 ◽  
Vol 1 ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Body Constitution

scholarly journals Reduced MLH3 Expression in the Syndrome of Gan-Shen Yin Deficiency in Patients with Different Diseases

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Juan Du ◽  
Maofeng Zhong ◽  
Dong Liu ◽  
Shufang Liang ◽  
Xiaolin Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Roc Analysis ◽  
Primary Liver Cancer ◽  
The Body ◽  
Metabolic Characteristics ◽  
Yin Deficiency ◽  
Body Constitution ◽  
Deficiency Group ◽  
The Relationship

Traditional Chinese medicine formulates treatment according to body constitution (BC) differentiation. Different constitutions have specific metabolic characteristics and different susceptibility to certain diseases. This study aimed to assess the characteristic genes of gan-shen Yin deficiency constitution in different diseases. Fifty primary liver cancer (PLC) patients, 94 hypertension (HBP) patients, and 100 diabetes mellitus (DM) patients were enrolled and classified into gan-shen Yin deficiency group and non-gan-shen Yin deficiency group according to the body constitution questionnaire to assess the clinical manifestation of patients. The mRNA expressions of 17 genes in PLC patients with gan-shen Yin deficiency were different from those without gan-shen Yin deficiency. However, considering all patients with PLC, HBP, and DM, only MLH3 was significantly lower in gan-shen Yin deficiency group than that in non-gen-shen Yin deficiency. By ROC analysis, the relationship between MLH3 and gan-shen Yin deficiency constitution was confirmed. Treatment of MLH3 (−/− and −/+) mice with Liuweidihuang wan, classical prescriptions for Yin deficiency, partly ameliorates the body constitution of Yin deficiency in MLH3 (−/+) mice, but not in MLH3 (−/−) mice. MLH3 might be one of material bases of gan-shen Yin deficiency constitution.

scholarly journals Association study of diabetes mellitus and body constitution of traditional Chinese medicine

2019 ◽  
Vol 02 (01) ◽  
pp. 1-6
Author(s):  
Nabijan Mohammadturusn ◽  
Yizhe Xu ◽  
Fei Xu ◽  
Yuanhao Zhang ◽  
Zihui Tang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Total Sample ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Epidemiological Evidence ◽  
Related Information ◽  
Body Constitution ◽  
Baseline Characteristics

Objective: We report on the association between traditional Chinese medicine (TCM) constitution and diabetes mellitus (DM) and provide epidemiological evidence for the theory of correlation between constitution and disease. Methods: A total of 3748 participants were used for data analysis, and all study subjects underwent a complete clinical baseline characteristics evaluation to collect related information. DM was determined by an oral glucose tolerance test. Multiple logistic regression (MLR) models were employed to detect the associations. Results: In total, 16.84% of the participants had DM in the total sample. Significant differences were found in age, height, weight, and heart rate, between the DM and non-DM groups. Univariate linear regression analyses indicated that the variables Qi_Deficient and Yang_Deficient were significantly associated with the outcome, and a negative correlation between TCM constitution and DM was found. After adjustment for relevant potential confounding factors, the MLR detected significant associations between both the Qi_Deficient and Yang_Deficient variables and DM ([Formula: see text]-value [Formula: see text] 0.015 for Qi_Deficient and [Formula: see text]-value [Formula: see text] for Yang_Deficient). In Qi_Deficient and Yin_Deficient participants, the odds ratios (ORs) for DM were 0.778 and 0.646, respectively. Conclusion: Qi_Deficient and Yang_Deficient were significantly associated with DM. These findings may provide insights for clinical practice for the prevention and diagnosis of DM.

scholarly journals Diabetes Mellitus, Cognitive Impairment, and Traditional Chinese Medicine

2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
S. W. Seto ◽  
G. Y. Yang ◽  
H. Kiat ◽  
A. Bensoussan ◽  
Y. W. Kwan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Side Effects ◽  
Traditional Chinese Medicine ◽  
Cognitive Dysfunction ◽  
Scientific Evidence ◽  
Cerebrovascular Disorders ◽  
Blood Glucose Control ◽  
Epidemiological Studies ◽  
Therapeutic Benefits

Diabetes mellitus (DM) is a metabolic disorder affecting a large number of people worldwide. Numerous studies have demonstrated that DM can cause damage to multiple systems, leading to complications such as heart disease, cancer, and cerebrovascular disorders. Numerous epidemiological studies have shown that DM is closely associated with dementia and cognition dysfunction, with recent research focusing on the role of DM-mediated cerebrovascular damage in dementia. Despite the therapeutic benefits of antidiabetic agents for the treatment of DM-mediated cognitive dysfunction, most of these pharmaceutical agents are associated with various undesirable side-effects and their long-term benefits are therefore in doubt. Early evidence exists to support the use of traditional Chinese medicine (TCM) interventions, which tend to have minimal toxicity and side-effects. More importantly, these TCM interventions appear to offer significant effects in reducing DM-related complications beyond blood glucose control. However, more research is needed to further validate these claims and to explore their relevant mechanisms of action. The aims of this paper are (1) to provide an updated overview on the association between DM and cognitive dysfunction and (2) to review the scientific evidence underpinning the use of TCM interventions for the treatment and prevention of DM-induced cognitive dysfunction and dementia.

scholarly journals Unrecognised underlying condition for COVID-19: perspective study of meridian and M-shaped male baldness

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Wen Sheng Zhou ◽  
Jian Bin Zhang
Keyword(s):  
Risk Factor ◽  
Chinese Medicine ◽  
Androgenetic Alopecia ◽  
Acupuncture Points ◽  
Body Type ◽  
Underlying Condition ◽  
High Severity ◽  
Body Constitution

Male androgenetic alopecia (MAA) is observed as a high severity risk factor but not listed within underlying COVID-19 conditionsdue to scanty available evidence. From a Chinese medicine (CM) perspective, the pathogenesis of MAA is overlapping with many recognised underlying conditions. This article compares CM meridian theory with MAA pattern progression to illustrate 1) the morphological and topographical superposition between the MAA progressing pattern and CM meridians, 2) damp-heat dominated body constitution presences among MAA patients as well as some underlying COVID-19 conditions, 3) vulnerable body type should be alerted and recognised to avoid an increase in infectious severity rate. The fundamental acupuncture points of treatment are provided for a concrete clarification of MAA.

scholarly journals Research progress on Traditional Chinese Medicine syndromes of diabetes mellitus

2020 ◽  
Vol 121 ◽  
pp. 109565 ◽  
Author(s):  
Jingkang Wang ◽  
Quantao Ma ◽  
Yaqi Li ◽  
Pengfei Li ◽  
Min Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Research Progress

scholarly journals Distribution of traditional Chinese medicine syndromes in type 2 diabetes mellitus with chronic heart failure

Medicine ◽  
2020 ◽  
Vol 99 (30) ◽  
pp. e21091
Author(s):  
Hui Wang ◽  
Jun Zhang ◽  
Chun-fang Shi ◽  
Jing Jia ◽  
Zhi-min Zhang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Chinese Medicine ◽  
Chronic Heart Failure ◽  
Traditional Chinese Medicine
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