scholarly journals The Effect of p53 Status of Tumor Cells on Radiosensitivity of Irradiated Tumors With Carbon-Ion Beams Compared With γ-Rays or Reactor Neutron Beams

2015 ◽  
Vol 6 (4) ◽  
pp. 398-409 ◽  
Author(s):  
Shin-ichiro Masunaga ◽  
Akiko Uzawa ◽  
Ryoichi Hirayama ◽  
Yoshitaka Matsumoto ◽  
Yoshinori Sakurai ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Ion Beams ◽  
Reactor Neutron ◽  
Carbon Ion ◽  
Neutron Beams ◽  
P53 Status ◽  
Γ Rays

Radiobiologic Significance of Response of Intratumor Quiescent Cells In Vivo to Accelerated Carbon Ion Beams Compared With γ-Rays and Reactor Neutron Beams

2008 ◽  
Vol 70 (1) ◽  
pp. 221-228 ◽  
Author(s):  
Shin-ichiro Masunaga ◽  
Koichi Ando ◽  
Akiko Uzawa ◽  
Ryoichi Hirayama ◽  
Yoshiya Furusawa ◽  
...  
Keyword(s):  
Ion Beams ◽  
Reactor Neutron ◽  
Carbon Ion ◽  
Quiescent Cells ◽  
Neutron Beams ◽  
Γ Rays

scholarly journals Prediction of Cellular Radiosensitivity from DNA Damage Induced by γ-Rays and Carbon Ion Irradiation in Canine Tumor Cells

2005 ◽  
Vol 67 (11) ◽  
pp. 1089-1095 ◽  
Author(s):  
Seiichi WADA ◽  
Tran Van KHOA ◽  
Yasuhiko KOBAYASHI ◽  
Tomoo FUNAYAMA ◽  
Kikumi OGIHARA ◽  
...  
Keyword(s):  
Dna Damage ◽  
Tumor Cells ◽  
Ion Irradiation ◽  
Cellular Radiosensitivity ◽  
Carbon Ion ◽  
Γ Rays ◽  
Canine Tumor

Abstract 4140: Role of nitric oxide in invasiveness of tumor cells irradiated with carbon-ion beams

2015 ◽  
Author(s):  
Mayumi Fujita ◽  
Kaori Imadome ◽  
Yoshimi Shoji ◽  
Robert Cheng ◽  
Aparna H. Kesarwala ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Tumor Cells ◽  
Ion Beams ◽  
Carbon Ion

scholarly journals Impact of the p53 Status of the Tumor Cells on the Effect of Reactor Neutron Beam Irradiation, with Emphasis on the Response of Intratumor Quiescent Cells

2002 ◽  
Vol 93 (12) ◽  
pp. 1366-1377 ◽  
Author(s):  
Shin-ichiro Masunaga ◽  
Koji Ono ◽  
Akihisa Takahashi ◽  
Yoshinori Sakurai ◽  
Ken Ohnishi ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Neutron Beam ◽  
Reactor Neutron ◽  
Beam Irradiation ◽  
Quiescent Cells ◽  
P53 Status

scholarly journals Mutational effects of γ-rays and carbon ion beams on Arabidopsis seedlings

2013 ◽  
Vol 54 (6) ◽  
pp. 1050-1056 ◽  
Author(s):  
Ryouhei Yoshihara ◽  
Shigeki Nozawa ◽  
Yoshihiro Hase ◽  
Issay Narumi ◽  
Jun Hidema ◽  
...  
Keyword(s):  
Ion Beams ◽  
Carbon Ion ◽  
Γ Rays

Comparative analysis of G2 arrest after irradiation with 75 keV carbon-ion beams and 137Cs γ-rays in a human lymphoblastoid cell line

2003 ◽  
Vol 27 (3) ◽  
pp. 222-228 ◽  
Author(s):  
Satoko Matsumura ◽  
Tatsushi Matsumura ◽  
Shuji Ozeki ◽  
Shoko Fukushima ◽  
Hideya Yamazaki ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Cell Line ◽  
Lymphoblastoid Cell Line ◽  
Ion Beams ◽  
G2 Arrest ◽  
Carbon Ion ◽  
Human Lymphoblastoid Cell ◽  
Human Lymphoblastoid Cell Line ◽  
Γ Rays

scholarly journals Metformin enhances the radiosensitivity of human liver cancer cells to γ-rays and carbon ion beams

Oncotarget ◽  
2016 ◽  
Vol 7 (49) ◽  
pp. 80568-80578 ◽  
Author(s):  
Eun Ho Kim ◽  
Mi-Sook Kim ◽  
Yoshiya Furusawa ◽  
Akiko Uzawa ◽  
Soorim Han ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Human Liver ◽  
Ion Beams ◽  
Carbon Ion ◽  
Liver Cancer Cells ◽  
Human Liver Cancer ◽  
Γ Rays ◽  
Human Liver Cancer Cells

scholarly journals Carbon ion radiotherapy for recurrent calf myxoid liposarcoma: a case report

2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110097
Author(s):  
Xiaojun Li ◽  
Yanshan Zhang ◽  
Yancheng Ye ◽  
Ying Qi ◽  
Chunlan Feng ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Myxoid Liposarcoma ◽  
Ion Beams ◽  
Carbon Ion Radiotherapy ◽  
Irradiation Damage ◽  
Radiation Dermatitis ◽  
Complete Disappearance ◽  
Carbon Ion ◽  
The Right

Liposarcoma (LPS) is the most common soft tissue sarcoma. Myxoid LPS (MLPS) is the second most common subtype of LPS and accounts for 25% to 50% of all LPSs. Like most other soft tissue sarcomas, the mainstay of treatment for LPS is inevitably surgery. Multidisciplinary approaches, including surgery, chemotherapy, and radiotherapy, have been successful in the treatment of LPS during the last three decades. Even so, recurrence of LPS remains challenging. Carbon ion beams produce increased energy deposition at the end of their range to form a Bragg peak while minimizing irradiation damage to surrounding tissues, which facilitates more precise dosage and localization than that achieved with photon beams. Furthermore, carbon ion beams have high relative biologic effectiveness. We herein describe a patient who developed recurrent MLPS in the right calf after two surgeries and underwent carbon ion radiotherapy (CIRT), achieving complete disappearance of the tumor. The patient developed Grade 1 radiation dermatitis 30 days after CIRT, but no other acute toxicities were observed. The tumor had completely disappeared by 120 days after CIRT, and the patient remained disease-free for 27 months after CIRT. The CARE guidelines were followed in the reporting of this case.

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