scholarly journals Multiple Metachronous Malignant Fibrous Histiocytomas of the Upper Limbs – a Case Report

2014 ◽  
Vol 27 (6) ◽  
pp. 438-441 ◽  
Author(s):  
Danijela Šćepanović ◽  
Andrea Masaryková ◽  
Margita Pobijáková ◽  
Alexandra Hanicová ◽  
Marta Fekete
Keyword(s):  
Case Report ◽  
Upper Limbs ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

scholarly journals Primary giant cell malignant fibrous histiocytoma-associated with renal calculus

2014 ◽  
Vol 8 (3-4) ◽  
pp. 193 ◽  
Author(s):  
Adem Altunkol ◽  
Murat Savas ◽  
Halil Ciftci ◽  
Mehmet Gulum ◽  
Ismail Yagmur ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Soft Tissue Sarcomas ◽  
Renal Calculus ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas ◽  
Visceral Organs

Malignant fibrous histiocytomas (MFH) are the most commonly seen soft tissue sarcomas in adults. It is rarely seen in some visceral organs. Kidneys are the parenchymal organs in which MFHs are most frequently seen. More than 50 cases of primary renal MFH have been reported. Among these cases, only 1 was reported as primary giant cell subtype in association with urolithiasis. This case report is the second such case with the these characteristics.

Two malignant fibrous histiocytomas in bone infarcts. Case report.

1983 ◽  
Vol 65 (8) ◽  
pp. 1166-1171 ◽  
Author(s):  
N G Heselson ◽  
S K Price ◽  
E E Mills ◽  
S S Conway ◽  
R K Marks
Keyword(s):  
Case Report ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

scholarly journals Lead Toxicity due to Ingestion of Lead-Contaminated Opium in a Patient Presenting with Motor Neuropathy and Upper Limb Paresis: A case report

2019 ◽  
Vol 18 (4) ◽  
pp. 529 ◽  
Author(s):  
Seyed M. M. Mirzaei ◽  
Ayob Akbari ◽  
Omid Mehrpour ◽  
Nasim Zamani
Keyword(s):  
Nervous System ◽  
Case Report ◽  
Lead Poisoning ◽  
Chelation Therapy ◽  
Lead Level ◽  
Lead Toxicity ◽  
Blood Lead ◽  
Motor Neuropathy ◽  
Upper Limbs ◽  
Gastrointestinal Complications

Opium users may present with central or peripheral nervous system-related symptoms, gastrointestinal complications and anaemia; in such cases, lead poisoning should be suspected and chelation therapy initiated as soon as possible. We report a 64-year-old male patient with a 20-year history of opium addiction who was referred to the Imam Reza Hospital, Birjand, Iran, in 2017 with severe motor neuropathy and paresis in both upper limbs. His primary symptoms were generalised weakness, abdominal and bone pain, constipation and lower limb paraesthesia that had started several months prior. In addition, he reported severe progressive bilateral paresis of the upper limbs of one month’s duration. A diagnosis of lead poisoning was confirmed by a blood lead level of 140 μg/dL. The patient underwent chelation therapy after which he improved significantly. At a one-year follow-up visit, he was neurologically intact and symptom-free.Keywords: Opium Dependence; Lead Poisoning; Lead-Induced Nervous System Diseases; Paresthesia; Case Report; Iran.

Malignant fibrous histiocytomas induced in rats by polymers

1984 ◽  
Vol 108 (3) ◽  
pp. 364-365 ◽  
Author(s):  
Akihiko Maekawa ◽  
Toshiaki Ogiu ◽  
Hiroshi Onodera ◽  
Kyoko Furuta ◽  
Chiaki Matsuoka ◽  
...  
Keyword(s):  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

ASK1(MAP3K5) as a potential therapeutic target in malignant fibrous histiocytomas with 12q14-q15 and 6q23 amplifications

2004 ◽  
Vol 40 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Frédéric Chibon ◽  
Odette Mariani ◽  
Josette Derré ◽  
Aline Mairal ◽  
Jean-Michel Coindre ◽  
...  
Keyword(s):  
Therapeutic Target ◽  
Potential Therapeutic Target ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

Vulvar sarcoma outcomes by histologic subtype: a Surveillance, Epidemiology, and End Results (SEER) database review

2020 ◽  
Vol 30 (8) ◽  
pp. 1118-1123
Author(s):  
Sarah Johnson ◽  
Malte Renz ◽  
Lindsay Wheeler ◽  
Elisabeth Diver ◽  
Oliver Dorigo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Seer Database ◽  
Disease Specific Survival ◽  
Histologic Subtype ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas ◽  
Disease Specific ◽  
Positive Lymph Nodes ◽  
End Results

ObjectiveVulvar cancers account for 5% of all gynecologic malignancies; only 1%–3% of those vulvar cancers are primary vulvar sarcomas. Given the rarity of vulvar sarcomas, outcome data specific to histopathologic subtypes are sparse. The aim of this study was to identify clinical and pathologic factors of primary vulvar sarcomas that are associated with survival and may inform treatment decisions.MethodsThe Surveillance, Epidemiology, and End Results (SEER) database was searched for women diagnosed with vulvar sarcoma between 1973 and 2018. We identified 315 patients and reviewed their demographic, clinicopathologic, surgical, and survival information. Statistical analyses included χ2 and t-tests, Kaplan–Meier survival, and Cox regression analyses.ResultsThe most common histopathologies of vulvar sarcomas were dermatofibrosarcomas (85/315, 27%) and leiomyosarcomas (72/315, 22.9%). Rhabdomyosarcomas (18/315, 5.7%), liposarcomas (16/315, 5.1%), and malignant fibrous histiocytomas (16/315, 5.1%) were less frequent. The majority of patients underwent surgery (292/315, 92.7%), which included lymph node dissections in 21.6% (63/292). Survival and lymph node involvement varied significantly with histologic subtype. The 5-year disease-specific survival for dermatofibrosarcomas, liposarcomas, and fibrosarcomas was 100% and only 60.3% and 62.5% for malignant fibrous histiocytomas and rhabdomyosarcomas, respectively. None of the patients with (dermato)fibrosarcomas, liposarcomas, or leiomyosarcomas had positive lymph nodes, in contrast to rhabdomyosarcomas and malignant fibrous histiocytomas with 77.8% and 40% positive lymph nodes, respectively. The 5-year disease-specific survival for women with positive lymph nodes was 0%.ConclusionsVulvar sarcomas are heterogeneous with survival highly dependent on the histopathologic subtype. While surgical excision is the mainstay of treatment for all vulvar sarcomas, staging lymphadenectomy should be deferred for (dermato)fibrosarcomas, liposarcomas, and leiomyosarcomas as there were no cases of lymph nodes metastases.

scholarly journals Diastrophic dysplasia: prenatal diagnosis and review of the literature

2013 ◽  
Vol 131 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Jonathan Celli Honório ◽  
Rafael Frederico Bruns ◽  
Luciana Fernandes Gründtner ◽  
Salmo Raskin ◽  
Lilian Pereira Ferrari ◽  
...  
Keyword(s):  
Case Report ◽  
Prenatal Diagnosis ◽  
Homozygous Mutation ◽  
Upper Limbs ◽  
Sulfate Transporter ◽  
Chain Reaction ◽  
Realistic Interpretation ◽  
Diastrophic Dysplasia ◽  
Ultrasound Findings ◽  
Polymerase Chain

CONTEXT Diastrophic dysplasia is a type of osteochondrodysplasia caused by homozygous mutation in the gene DTDST (diastrophic dysplasia sulfate transporter gene). Abnormalities occurring particularly in the skeletal and cartilaginous system are typical of the disease, which has an incidence of 1 in 100,000 live births. CASE REPORT The case of a pregnant woman, without any consanguineous relationship with her husband, whose fetus was diagnosed with skeletal dysplasia based on ultrasound findings and DNA tests, is described. An obstetric ultrasound scan produced in the 16th week of gestation revealed characteristics that guided the clinical diagnosis. Prominent among these characteristics were rhizomelia of the lower and upper limbs (shortening of the proximal portions) and mesomelia (shortening of the intermediate portions). Both upper limbs showed marked curvature, with the first finger of the upper limbs in abduction and clinodactyly of the fifth finger. Molecular analysis using the polymerase chain reaction (PCR) and gene sequencing detected mutations that had already been described in the literature for the gene DTDST, named c.862C > T and c.2147_2148insCT. Therefore, the fetus was a compound heterozygote, carrying two different mutations. CONCLUSIONS Prenatal diagnosis of this condition allowed a more realistic interpretation of the prognosis, and of the couple's reproductive future. This case report shows the contribution of molecular genetics towards the prenatal diagnosis, for which there are few descriptions in the literature.

Malignant fibrous histiocytomas in children

1984 ◽  
Vol 19 (1) ◽  
pp. 81-83 ◽  
Author(s):  
Tom Tracy ◽  
James P. Neifeld ◽  
Richard M. DeMay ◽  
Arnold M. Salzberg
Keyword(s):  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas
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