Malignant fibrous histiocytomas induced in rats by polymers

1984 ◽  
Vol 108 (3) ◽  
pp. 364-365 ◽  
Author(s):  
Akihiko Maekawa ◽  
Toshiaki Ogiu ◽  
Hiroshi Onodera ◽  
Kyoko Furuta ◽  
Chiaki Matsuoka ◽  
...  
Keyword(s):  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

ASK1(MAP3K5) as a potential therapeutic target in malignant fibrous histiocytomas with 12q14-q15 and 6q23 amplifications

2004 ◽  
Vol 40 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Frédéric Chibon ◽  
Odette Mariani ◽  
Josette Derré ◽  
Aline Mairal ◽  
Jean-Michel Coindre ◽  
...  
Keyword(s):  
Therapeutic Target ◽  
Potential Therapeutic Target ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

Vulvar sarcoma outcomes by histologic subtype: a Surveillance, Epidemiology, and End Results (SEER) database review

2020 ◽  
Vol 30 (8) ◽  
pp. 1118-1123
Author(s):  
Sarah Johnson ◽  
Malte Renz ◽  
Lindsay Wheeler ◽  
Elisabeth Diver ◽  
Oliver Dorigo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Seer Database ◽  
Disease Specific Survival ◽  
Histologic Subtype ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas ◽  
Disease Specific ◽  
Positive Lymph Nodes ◽  
End Results

ObjectiveVulvar cancers account for 5% of all gynecologic malignancies; only 1%–3% of those vulvar cancers are primary vulvar sarcomas. Given the rarity of vulvar sarcomas, outcome data specific to histopathologic subtypes are sparse. The aim of this study was to identify clinical and pathologic factors of primary vulvar sarcomas that are associated with survival and may inform treatment decisions.MethodsThe Surveillance, Epidemiology, and End Results (SEER) database was searched for women diagnosed with vulvar sarcoma between 1973 and 2018. We identified 315 patients and reviewed their demographic, clinicopathologic, surgical, and survival information. Statistical analyses included χ2 and t-tests, Kaplan–Meier survival, and Cox regression analyses.ResultsThe most common histopathologies of vulvar sarcomas were dermatofibrosarcomas (85/315, 27%) and leiomyosarcomas (72/315, 22.9%). Rhabdomyosarcomas (18/315, 5.7%), liposarcomas (16/315, 5.1%), and malignant fibrous histiocytomas (16/315, 5.1%) were less frequent. The majority of patients underwent surgery (292/315, 92.7%), which included lymph node dissections in 21.6% (63/292). Survival and lymph node involvement varied significantly with histologic subtype. The 5-year disease-specific survival for dermatofibrosarcomas, liposarcomas, and fibrosarcomas was 100% and only 60.3% and 62.5% for malignant fibrous histiocytomas and rhabdomyosarcomas, respectively. None of the patients with (dermato)fibrosarcomas, liposarcomas, or leiomyosarcomas had positive lymph nodes, in contrast to rhabdomyosarcomas and malignant fibrous histiocytomas with 77.8% and 40% positive lymph nodes, respectively. The 5-year disease-specific survival for women with positive lymph nodes was 0%.ConclusionsVulvar sarcomas are heterogeneous with survival highly dependent on the histopathologic subtype. While surgical excision is the mainstay of treatment for all vulvar sarcomas, staging lymphadenectomy should be deferred for (dermato)fibrosarcomas, liposarcomas, and leiomyosarcomas as there were no cases of lymph nodes metastases.

Malignant fibrous histiocytomas in children

1984 ◽  
Vol 19 (1) ◽  
pp. 81-83 ◽  
Author(s):  
Tom Tracy ◽  
James P. Neifeld ◽  
Richard M. DeMay ◽  
Arnold M. Salzberg
Keyword(s):  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

scholarly journals Retroperitoneal liposarcomas: Follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas

Cancer ◽  
2006 ◽  
Vol 106 (12) ◽  
pp. 2725-2733 ◽  
Author(s):  
Elizabeth Fabre-Guillevin ◽  
Jean-Michel Coindre ◽  
Nicolas de Saint Aubain Somerhausen ◽  
Francoise Bonichon ◽  
Eberhard Stoeckle ◽  
...  
Keyword(s):  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas

Malignant Fibrous Histiocytomas Associated with the Urinary Tract

1988 ◽  
Vol 62 (5) ◽  
pp. 488-489 ◽  
Author(s):  
D. A. REW ◽  
C. R. J. WOODHOUSE ◽  
R. J. SHEARER ◽  
C. M. CORBISHLEY
Keyword(s):  
Urinary Tract ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas
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