Guidelines for the administration of biological therapy in patients with inflammatory bowel diseases: fourth, updated edition

2019 ◽  
Vol 73 (1) ◽  
pp. 11-24 ◽  
Author(s):  
Martin Bortlík ◽  
Dana Ďuricová ◽  
Tomáš Douda ◽  
Michal Konečný ◽  
Jana Koželuhová ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Biological Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Biological therapy and surgery rates in inflammatory bowel diseases – Data analysis of almost 1000 patients from a Hungarian tertiary IBD center

PLoS ONE ◽  
2018 ◽  
Vol 13 (7) ◽  
pp. e0200824 ◽  
Author(s):  
Kata Szántó ◽  
Tibor Nyári ◽  
Anita Bálint ◽  
Renáta Bor ◽  
Ágnes Milassin ◽  
...  
Keyword(s):  
Data Analysis ◽  
Inflammatory Bowel Diseases ◽  
Biological Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Surgery Rates

scholarly journals Expression of CD44 in Monocyte and Lymphocyte Subpopulations in Patients With Inflammatory Bowel Diseases

2021 ◽  
Author(s):  
Ivana Franić ◽  
Nikolina Režić Mužinić ◽  
Anita Markotić ◽  
Piero Marin Živković ◽  
Marino Vilović ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Inflammatory Bowel Diseases ◽  
Disease Duration ◽  
Biological Therapy ◽  
Cd44 Expression ◽  
Bowel Diseases ◽  
Monocyte Subpopulations ◽  
Inflammatory Bowel ◽  
Lower Expression

Abstract CD44 expressed in monocytes and lymphocytes seems to play a crucial role in gastrointestinal inflammation, such as the one occurring in the context of inflammatory bowel diseases (IBD). Differentially methylated genes are distinctly expressed across monocyte subpopulations related to the state of Crohn's disease. Hence, the aim of this study was to detect CD44 expression at monocyte subpopulations, lymphocytes and granulocytes in relation to the type of IBD, therapy and disease duration. Monocyte subpopulations CD14++CD16−, CD14+CD16++ and CD14+CD16+, as well as other leukocytes, were analyzed for their CD44 expression using flow cytometry in 46 patients with IBD and 48 healthy controls. Patients with Crohn's disease treated with non-biological therapy (NBT) exhibited lower percentage of anti-inflammatory CD14+CD16++ monocytes, whereas NBT-treated patients with ulcerative colitis had lower expression of CD44 on CD14+CD44+ lymphocytes, in comparison to controls, respectively. Conversely, patients with Crohn's disease treated with biological therapy had higher percentage of CD44+ granulocytes, but lower expression of CD44 on anti-inflammatory monocytes compared to controls. Percentage of classical CD14++CD16- monocytes was lower in the <9 years of IBD duration subgroup, compared with the longer disease duration subgroup. The present study addresses the putative role of differentiation and regulation of monocyte and lymphocyte cells in tailoring IBD therapeutic regimes.

Accurate and rapid microfluidic ELISA to monitor Infliximab titers in patients with inflammatory bowel diseases

The Analyst ◽  
2022 ◽  
Author(s):  
Inês Iria ◽  
Ruben R.G. Soares ◽  
Eduardo Brás ◽  
Virginia Chu ◽  
João Gonçalves ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Gastrointestinal Tract ◽  
Chronic Inflammation ◽  
Inflammatory Bowel Diseases ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Inflammatory bowel disease (IBD) is a term used to describe disorders that involve chronic inflammation in the gastrointestinal tract, affecting more than 6.8 million people worldwide.1 Biological therapy is used...

Early onset inflammatory bowel diseases and biological therapy: Results from the Sicilian Network

2017 ◽  
Vol 49 (4) ◽  
pp. e257
Author(s):  
S. Accomando ◽  
M. Citrano ◽  
S. Valenti ◽  
F. Graziano ◽  
C. Romano
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Early Onset ◽  
Biological Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel

BIOLOGICAL THERAPY IN INFLAMMATORY BOWEL DISEASES: SAFETY PROFILE

2015 ◽  
Vol 10 (999) ◽  
pp. 1-1
Author(s):  
Antonio Di Sario ◽  
Emanuele Bendia ◽  
Laura Schiadà ◽  
Paola Sassaroli ◽  
Antonio Benedetti
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Safety Profile ◽  
Biological Therapy ◽  
Bowel Diseases ◽  
Inflammatory Bowel
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