scholarly journals Risk of Cancer Following Lumbar Fusion Surgery With Recombinant Human Bone Morphogenic Protein-2 (rhBMP-2): An Analysis Using a Commercially Insured Patient Population

2018 ◽  
Vol 12 (2) ◽  
pp. 260-268 ◽  
Author(s):  
GREGORY S. COOPER ◽  
TZUYUNG DOUG KOU
Keyword(s):  
Patient Population ◽  
Lumbar Fusion ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Fusion Surgery ◽  
Lumbar Fusion Surgery ◽  
Risk Of Cancer ◽  
Bone Morphogenic Protein 2 ◽  
Insured Patient ◽  
Recombinant Human Bone

Complications Associated With the Use of Recombinant Human Bone Morphogenic Protein–2 in Ridge Augmentation: A Case Report

2017 ◽  
Vol 43 (5) ◽  
pp. 351-359 ◽  
Author(s):  
Panagiotis Dragonas ◽  
Charles Palin ◽  
Saba Khan ◽  
Praveen K. Gajendrareddy ◽  
Whitney D. Weiner
Keyword(s):  
Case Report ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Therapy Outcomes ◽  
Bone Maturation ◽  
Ridge Augmentation ◽  
Implant Placement ◽  
Implant Dentistry ◽  
Bone Morphogenic Protein 2 ◽  
Recombinant Human Bone

This case report aims to describe in detail a complication associated with resorption of regenerated bone following implant placement and ridge augmentation using recombinant human bone morphogenic protein–2 (rhBMP-2) in combination with allograft and xenograft. Bilateral maxillary sinus and ridge augmentation procedures were completed using rhBMP-2 combined with allograft and xenograft. Five months later, significant bone augmentation was achieved, which allowed for the placement of 4 implants. Upon stage 2 surgery, significant dehiscence was noted in all implants. Treatment steps to address this complication included implant removal, guided bone regeneration with xenograft only, and placement of new implants followed by soft-tissue grafting. At the time of publication, this patient is status 1½ years post case completion with maintenance of therapy outcomes. Off-label use of rhBMP-2 has gained significant acceptance in implant dentistry. However, there is limited evidence regarding the bone maturation process when rhBMP-2 is combined with other biomaterials. More research may be needed regarding the timing and process of bone healing in the presence of rhBMP-2, in an effort to avoid surgical complications.

scholarly journals Does Recombinant Human Bone Morphogenic Protein 2 Affect Perioperative Blood Loss after Lumbar and Thoracic Spinal Fusion?

2018 ◽  
Vol 12 (5) ◽  
pp. 880-886 ◽  
Author(s):  
Nathan Wanderman ◽  
Bayard Carlson ◽  
William Robinson ◽  
Mohamad Bydon ◽  
Michael Yaszemski ◽  
...  
Keyword(s):  
Blood Loss ◽  
Spinal Fusion ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Perioperative Blood Loss ◽  
Thoracic Spinal ◽  
Bone Morphogenic Protein 2 ◽  
Recombinant Human Bone

Bone union rate with recombinant human bone morphogenic protein-2 versus autologous iliac bone in PEEK cages for anterior lumbar interbody fusion

2014 ◽  
Vol 38 (9) ◽  
pp. 2001-2007 ◽  
Author(s):  
Charles-Henri Flouzat-Lachaniette ◽  
Amir Ghazanfari ◽  
Charlie Bouthors ◽  
Alexandre Poignard ◽  
Philippe Hernigou ◽  
...  
Keyword(s):  
Interbody Fusion ◽  
Anterior Lumbar Interbody Fusion ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Iliac Bone ◽  
Bone Union ◽  
Lumbar Interbody Fusion ◽  
Union Rate ◽  
Bone Morphogenic Protein 2 ◽  
Recombinant Human Bone
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