scholarly journals Use of three‐dimensionally printed β‐tricalcium phosphate synthetic bone graft combined with recombinant human bone morphogenic protein‐2 to treat a severe radial atrophic nonunion in a Yorkshire terrier

2020 ◽  
Vol 49 (8) ◽  
pp. 1626-1631
Author(s):  
Jordi Franch ◽  
Albert Barba ◽  
Katrin Rappe ◽  
Yassine Maazouz ◽  
Maria‐Pau Ginebra
Keyword(s):  
Bone Graft ◽  
Tricalcium Phosphate ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Synthetic Bone ◽  
Synthetic Bone Graft ◽  
Bone Morphogenic Protein 2 ◽  
Atrophic Nonunion ◽  
Recombinant Human Bone ◽  
Yorkshire Terrier

Complications Associated With the Use of Recombinant Human Bone Morphogenic Protein–2 in Ridge Augmentation: A Case Report

2017 ◽  
Vol 43 (5) ◽  
pp. 351-359 ◽  
Author(s):  
Panagiotis Dragonas ◽  
Charles Palin ◽  
Saba Khan ◽  
Praveen K. Gajendrareddy ◽  
Whitney D. Weiner
Keyword(s):  
Case Report ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Therapy Outcomes ◽  
Bone Maturation ◽  
Ridge Augmentation ◽  
Implant Placement ◽  
Implant Dentistry ◽  
Bone Morphogenic Protein 2 ◽  
Recombinant Human Bone

This case report aims to describe in detail a complication associated with resorption of regenerated bone following implant placement and ridge augmentation using recombinant human bone morphogenic protein–2 (rhBMP-2) in combination with allograft and xenograft. Bilateral maxillary sinus and ridge augmentation procedures were completed using rhBMP-2 combined with allograft and xenograft. Five months later, significant bone augmentation was achieved, which allowed for the placement of 4 implants. Upon stage 2 surgery, significant dehiscence was noted in all implants. Treatment steps to address this complication included implant removal, guided bone regeneration with xenograft only, and placement of new implants followed by soft-tissue grafting. At the time of publication, this patient is status 1½ years post case completion with maintenance of therapy outcomes. Off-label use of rhBMP-2 has gained significant acceptance in implant dentistry. However, there is limited evidence regarding the bone maturation process when rhBMP-2 is combined with other biomaterials. More research may be needed regarding the timing and process of bone healing in the presence of rhBMP-2, in an effort to avoid surgical complications.

scholarly journals Does Recombinant Human Bone Morphogenic Protein 2 Affect Perioperative Blood Loss after Lumbar and Thoracic Spinal Fusion?

2018 ◽  
Vol 12 (5) ◽  
pp. 880-886 ◽  
Author(s):  
Nathan Wanderman ◽  
Bayard Carlson ◽  
William Robinson ◽  
Mohamad Bydon ◽  
Michael Yaszemski ◽  
...  
Keyword(s):  
Blood Loss ◽  
Spinal Fusion ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Perioperative Blood Loss ◽  
Thoracic Spinal ◽  
Bone Morphogenic Protein 2 ◽  
Recombinant Human Bone

scholarly journals Fosfato β-Tricálcico Monobloco no Tratamento de Fraturas Proximais do Úmero Cirúrgicas

2016 ◽  
Vol 29 (1) ◽  
pp. 41
Author(s):  
Marco Sarmento ◽  
Samuel Martins ◽  
Jacinto Monteiro
Keyword(s):  
Bone Graft ◽  
Range Of Motion ◽  
Tricalcium Phosphate ◽  
Functional Results ◽  
Proximal Humeral Fractures ◽  
Humeral Fractures ◽  
Synthetic Bone ◽  
Synthetic Bone Graft ◽  
Shoulder Range Of Motion ◽  
Shoulder Range

<p><strong>Introduction:</strong> The proximal humeral fractures are becoming more frequent, with a greater tendency for its surgical treatment by osteosynthesis with plate and locked screws. The mechanical and biological failure in these fractures and devices, despite the evolution of this type of implants, highlighted the synthetic bone grafts became an option.<br /><strong>Material and Methods:</strong> Over a period of 96 months, patients considered were those with proximal humeral fractures treated surgically with a plate and locked screws, and in which β-tricalcium phosphate bone graft had been used. Functional results were evaluated by the shoulder range of motion as the radiological results.<br /><strong>Results:</strong> In 19 patients, with a medial follow up of 53 months, we obtained an average shoulder range of motion of 140º in abduction, 142º in forward flexion, 37º in external rotation and L3 hand position in internal rotation for a cefalo-diaphyseal angle of 136º.<br /><strong>Discussion:</strong> The β-tricalcium phosphate synthetic bone graft allows the maintenance of reduction after fixation of proximal humeral fractures stabilized with plate and locked screws. This reduction which means the maintenance of cefalo-diaphyseal angle is in close relationship with functional results as shown by shoulder range of motion in all planes.<br /><strong>Conclusion:</strong> The β-tricalcium phosphate synthetic bone graft should be seen as an adjuvant therapy in extramedullary fixation of proximal humeral fractures, especially those with greater comminution of the medial calcar.</p>

Bone union rate with recombinant human bone morphogenic protein-2 versus autologous iliac bone in PEEK cages for anterior lumbar interbody fusion

2014 ◽  
Vol 38 (9) ◽  
pp. 2001-2007 ◽  
Author(s):  
Charles-Henri Flouzat-Lachaniette ◽  
Amir Ghazanfari ◽  
Charlie Bouthors ◽  
Alexandre Poignard ◽  
Philippe Hernigou ◽  
...  
Keyword(s):  
Interbody Fusion ◽  
Anterior Lumbar Interbody Fusion ◽  
Bone Morphogenic Protein ◽  
Human Bone ◽  
Iliac Bone ◽  
Bone Union ◽  
Lumbar Interbody Fusion ◽  
Union Rate ◽  
Bone Morphogenic Protein 2 ◽  
Recombinant Human Bone
Sign in / Sign up

Export Citation Format

Share Document