scholarly journals Association of candidate gene polymorphisms for autoimmune thyroid diseases in patients with familial diffuse toxic goiter and autoimmune thyroiditis

2016 ◽  
Vol 12 (2) ◽  
pp. 46
Author(s):  
Oksana D. Rymar ◽  
Anna K. Mikitinskaya ◽  
Vladimir N. Maksivov ◽  
Sergei G. Shahmatov ◽  
Yuliya V. Schepina ◽  
...  
Keyword(s):  
Candidate Gene ◽  
Autoimmune Thyroiditis ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Toxic Goiter

Association of cytokine Th2 gene polymorphisms with autoimmune thyroid diseases in Tunisian population

2020 ◽  
Vol 47 (3) ◽  
pp. 294-308 ◽  
Author(s):  
Souhir Mestiri ◽  
Ines Zaaber ◽  
Oumaima Inoubli ◽  
Nabil Abid ◽  
Abir Omrani ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

Associations of gene polymorphisms in interferon‐alpha signature‐related genes with autoimmune thyroid diseases

2019 ◽  
Vol 91 (6) ◽  
pp. 860-868 ◽  
Author(s):  
Jiunn‐Diann Lin ◽  
Shun‐Fa Yang ◽  
Yuan‐Hung Wang ◽  
Wen‐Fang Fang ◽  
Kam‐Tsun Tang ◽  
...  
Keyword(s):  
Interferon Alpha ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

A potential role of TNFR gene polymorphisms in autoimmune thyroid diseases in the Tunisian population

Cytokine ◽  
2008 ◽  
Vol 43 (2) ◽  
pp. 110-113 ◽  
Author(s):  
Maha Kammoun-Krichen ◽  
Noura Bougacha-Elleuch ◽  
Kaouthar Makni ◽  
Mouna Mnif ◽  
Joumaa Jouida ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Potential Role ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association between STAT4 Gene Polymorphisms and Autoimmune Thyroid Diseases in a Chinese Population

2014 ◽  
Vol 15 (7) ◽  
pp. 12280-12293 ◽  
Author(s):  
Ni Yan ◽  
Shuai Meng ◽  
Jiaozhen Zhou ◽  
Jian Xu ◽  
Fatuma Muhali ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Chinese Population ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association between C1q gene polymorphisms and autoimmune thyroid diseases

2017 ◽  
Vol 61 (4) ◽  
pp. 337-342
Author(s):  
Qiuming Yao ◽  
Jie Li ◽  
Xiaofei An ◽  
Wenjuan Jiang ◽  
Qiu Qin ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals The value of central regulators of the immune response in the development of autoimmune thyroid diseases

2020 ◽  
Vol 65 (6) ◽  
pp. 458-465
Author(s):  
Ekaterina A. Troshina ◽  
Evgeniya S. Senyushkina
Keyword(s):  
Immune Response ◽  
Autoimmune Thyroiditis ◽  
Inflammatory Responses ◽  
Thyroid Diseases ◽  
Graves Disease ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Number Of Factors ◽  
Complex Process ◽  
Wide Range

The specific relationship between the endocrine and immune systems is represented by a numerous number of factors and mechanisms that form the structure and ensure the function of each of the two systems. For example, immunocompetent cells can produce immunologically active substances, as well as some hormones. On the other hand, immune cells are available to the effects of endogenous hormones. Currently, the so-called cross-regulation of endocrine and immune mechanisms in an equilibrium of pro-and anti-inflammatory responses has not been sufficiently studied. Among other autoimmune lesions, autoimmune thyreopathy occupies a significant place. The development of an autoimmune lesion of the thyroid gland is a complex process, which is the result of the interaction of infiltrating lymphocyte and thyrocyte tissue that can express a wide range of molecules involved in the immune response. Immunological and immunogenetic factors play a major role in the pathogenesis of autoimmune thyroid diseases, such as autoimmune thyroiditis and Graves disease. Despite the fact that more than 100 years have passed since the first description of autoimmune thyroiditis and Graves disease has been known for many centuries, the mechanisms of these pathologies are still not fully understood.

scholarly journals CTLA-4 gene polymorphisms and their influence on predisposition to autoimmune thyroid diseases (Graves’ disease and Hashimoto’s thyroiditis)

2012 ◽  
Vol 3 ◽  
pp. 415-421 ◽  
Author(s):  
Dorota Pastuszak-Lewandoska ◽  
Ewa Sewerynek ◽  
Daria Domańska ◽  
Aleksandra Gładyś ◽  
Renata Skrzypczak ◽  
...  
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Hashimoto's Thyroiditis ◽  
Graves Disease ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals The levels of immunoreactive proteins and cytokines in the blood of the patients presenting with autoimmune thyroid diseases

2014 ◽  
Vol 60 (6) ◽  
pp. 10-13 ◽  
Author(s):  
T P Maklakova ◽  
V N Zorina ◽  
T T Shapel’ ◽  
O N Boiko ◽  
R M Zorina ◽  
...  
Keyword(s):  
Risk Factor ◽  
Immune System ◽  
Autoimmune Thyroiditis ◽  
Tnf Alpha ◽  
Hormonal Status ◽  
Free T4 ◽  
Autoimmune Thyroid Diseases ◽  
Ifn Gamma ◽  
Autoimmune Thyroid ◽  
Toxic Goiter

We determined the levels of TSH, free T4 (fT4), immunoregulatory proteins (alpha-2-macroglobulin (α2-MG), lactoferrin (LF), alpha-1-antitripsin (α1-AT) , and cytokines (TNF-alpha, IL-6, IFN-gamma)) in the blood of 50 women presenting with diffuse toxic goiter (DTG) and 35 women with autoimmune thyroiditis (AIT) before and 4-6 months after the treatment. Thirty healthy women served as controls. Hypothyroidism in the outcome of AIT was associated with hypercytokinemia and the enhanced levels of a2-MG and LF, but not a1-AT. The treatment had no effect on these parameters but normalized the TSH and T4 levels. Manifest DTG was associated with the increased IFN-gamma, IL-6, α2-MG, LF, and α1-AT levels . The treatment during 4-6 months resulted in the reduction of the IL-6 and α2-MG levels whereas the hormonal status of the patients became normal. The persistence of certain disturbances suggested that dysfunction of the immune system was not totally corrected despite the normalization of the hormonal status and could be interpreted as the risk factor of a relapse of thyroid pathology.

CTLA4 Gene Polymorphisms in Children and Adolescents with Autoimmune Thyroid Diseases

2008 ◽  
Vol 12 (3) ◽  
pp. 461-464 ◽  
Author(s):  
Ediz Yeşilkaya ◽  
Altuğ Koç ◽  
Aysun Bideci ◽  
Orhun Çamurdan ◽  
Mehmet Boyraz ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Ctla4 Gene
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