Association of cytokine Th2 gene polymorphisms with autoimmune thyroid diseases in Tunisian population

2020 ◽  
Vol 47 (3) ◽  
pp. 294-308 ◽  
Author(s):  
Souhir Mestiri ◽  
Ines Zaaber ◽  
Oumaima Inoubli ◽  
Nabil Abid ◽  
Abir Omrani ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

A potential role of TNFR gene polymorphisms in autoimmune thyroid diseases in the Tunisian population

Cytokine ◽  
2008 ◽  
Vol 43 (2) ◽  
pp. 110-113 ◽  
Author(s):  
Maha Kammoun-Krichen ◽  
Noura Bougacha-Elleuch ◽  
Kaouthar Makni ◽  
Mouna Mnif ◽  
Joumaa Jouida ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Potential Role ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

Associations of gene polymorphisms in interferon‐alpha signature‐related genes with autoimmune thyroid diseases

2019 ◽  
Vol 91 (6) ◽  
pp. 860-868 ◽  
Author(s):  
Jiunn‐Diann Lin ◽  
Shun‐Fa Yang ◽  
Yuan‐Hung Wang ◽  
Wen‐Fang Fang ◽  
Kam‐Tsun Tang ◽  
...  
Keyword(s):  
Interferon Alpha ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association between STAT4 Gene Polymorphisms and Autoimmune Thyroid Diseases in a Chinese Population

2014 ◽  
Vol 15 (7) ◽  
pp. 12280-12293 ◽  
Author(s):  
Ni Yan ◽  
Shuai Meng ◽  
Jiaozhen Zhou ◽  
Jian Xu ◽  
Fatuma Muhali ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Chinese Population ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association between C1q gene polymorphisms and autoimmune thyroid diseases

2017 ◽  
Vol 61 (4) ◽  
pp. 337-342
Author(s):  
Qiuming Yao ◽  
Jie Li ◽  
Xiaofei An ◽  
Wenjuan Jiang ◽  
Qiu Qin ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals CTLA-4 gene polymorphisms and their influence on predisposition to autoimmune thyroid diseases (Graves’ disease and Hashimoto’s thyroiditis)

2012 ◽  
Vol 3 ◽  
pp. 415-421 ◽  
Author(s):  
Dorota Pastuszak-Lewandoska ◽  
Ewa Sewerynek ◽  
Daria Domańska ◽  
Aleksandra Gładyś ◽  
Renata Skrzypczak ◽  
...  
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Hashimoto's Thyroiditis ◽  
Graves Disease ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Implication of VDR rs7975232 and FCGR2A rs1801274 gene polymorphisms in the risk and the prognosis of autoimmune thyroid diseases in the Tunisian population

2020 ◽  
Vol 23 (1) ◽  
pp. 69-76
Author(s):  
S Mestiri ◽  
I Zaaber ◽  
I Nasr ◽  
H Marmouch
Keyword(s):  
Fragment Length Polymorphism ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Thyroglobulin Antibody ◽  
Significant Difference ◽  
Pcr Rflp ◽  
Mutation System ◽  
Polymerase Chain

AbstractHashimoto’s thyroiditis (HT) and Graves’ disease (GD) are autoimmune thyroid diseases (AITD) that cause hypothyroidism and hyperthyroidism, respectively. The vitamin D receptor (VDR) and the Fey receptor IIA (FcγRIIA), are implicated in the etiology of AITD. This study was conducted to examine the implication of VDR rs7975232 and FCGR2A rs 1801274 variations in the susceptibility and the prognosis of AITD in the Tunisian population. The rs7975232 and rs1801274 (R131H) polymorphisms were analyzed in 162 controls and 162 AITD patients (106 HT and 56 GD) by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and amplification of refractory mutation system-PCR (ARMS-PCR), respectively. No significant difference was demonstrated for the rs7975232 between patients and controls. However, a significant association was shown between the rs1801274 polymorphism and AITD or HT in the dominant (p = 0.03 or p = 0.01), codominant (p = 0.019 or p = 0.026) and allelic (p = 0.011 or p = 0.012) models. The rs7975232 was associated with the absence or the presence of anti-thyroglobulin antibody, with the age of AITD and GD patients during the first diagnosis (p = 0.01 and p = 0.009, respectively) and with a high T4 level at the beginning of HT disease. However, the FCGR2A gene polymorphism was associated with a low T4 level at the beginning of GD disease. In conclusion, this study indicates that only the FCGR2A variation could be related to AITD and HT susceptibility and that VDR and FCGR2A gene variations constitute factors to prognosticate the severity of AITD, HT and GD.

Association ofInterleukin-1BandInterleukin-4Gene Variants with Autoimmune Thyroid Diseases in Tunisian Population

2016 ◽  
Vol 45 (4) ◽  
pp. 284-297 ◽  
Author(s):  
Ines Zaaber ◽  
Souhir Mestiri ◽  
Hounayda Hammedi ◽  
Hela Marmouch ◽  
Silvia Mahjoub ◽  
...  
Keyword(s):  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

CTLA4 Gene Polymorphisms in Children and Adolescents with Autoimmune Thyroid Diseases

2008 ◽  
Vol 12 (3) ◽  
pp. 461-464 ◽  
Author(s):  
Ediz Yeşilkaya ◽  
Altuğ Koç ◽  
Aysun Bideci ◽  
Orhun Çamurdan ◽  
Mehmet Boyraz ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Ctla4 Gene

scholarly journals Analysis of Associations of Human BAFF Gene Polymorphisms with Autoimmune Thyroid Diseases

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0154436 ◽  
Author(s):  
Jiunn-Diann Lin ◽  
Shun-Fa Yang ◽  
Yuan-Hung Wang ◽  
Wen-Fang Fang ◽  
Ying-Chin Lin ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid
Sign in / Sign up

Export Citation Format

Share Document