scholarly journals Ectopic calcitonin secretion in a woman with large cell neuroendocrine lung carcinoma

HORMONES ◽  
2013 ◽  
Vol 12 (4) ◽  
pp. 584-590 ◽  
Author(s):  
Goran Cvijovic ◽  
Dragan Micic ◽  
Aleksandra Kendereski ◽  
Svetlana Zoric ◽  
Mirjana Sumarac-Dumanovic ◽  
...  
Keyword(s):  
Lung Carcinoma ◽  
Large Cell ◽  
Calcitonin Secretion

Peripheral T-cell repertoire alterations are common and affect outcome in large cell neuroendocrine lung carcinoma

Pneumologie ◽  
2018 ◽  
Vol 72 (S 01) ◽  
pp. S53-S54
Author(s):  
P Christopoulos ◽  
M Schneider ◽  
F Bozorgmehr ◽  
W Engel-Riedel ◽  
C Kropf-Sanchen ◽  
...  
Keyword(s):  
T Cell ◽  
Lung Carcinoma ◽  
Large Cell ◽  
T Cell Repertoire ◽  
Cell Repertoire

scholarly journals Intracardiac Metastasis from a Large Cell Neuroendocrine Lung Carcinoma

2019 ◽  
Vol 08 (01) ◽  
pp. e41-e43
Author(s):  
Christopher Gaisendrees ◽  
Kaveh Eghbalzadeh ◽  
Navid Mader ◽  
Thorsten C. W. Wahlers
Keyword(s):  
Lung Carcinoma ◽  
Malignant Tumors ◽  
Close Contact ◽  
Large Cell ◽  
Cardiac Metastasis ◽  
Cardiac Tumors ◽  
Cardiac Metastases ◽  
The Right ◽  
Cava Vein ◽  
Inferior Cava Vein

AbstractPrimary malignant tumors of the heart are rare; the biggest group is sarcomas. Cardiac metastases make up the biggest group of secondary cardiac tumors. We present a rare case of cardiac metastasis (3.1 × 3.2 × 2.8 cm) localized in the right atrium, originating from a large cell neuroendocrine lung carcinoma, with close contact to the tricuspid valve and inferior cava vein.

scholarly journals Spontaneous Regression of a G-CSF-producing Large Cell Lung Carcinoma

Haigan ◽  
2013 ◽  
Vol 53 (3) ◽  
pp. 227-233 ◽  
Author(s):  
Yasutaka Kawai ◽  
Noriaki Sukoh ◽  
Shinichi Fukumoto ◽  
Yutaka Takeuchi ◽  
Satoshi Oizumi ◽  
...  
Keyword(s):  
Lung Carcinoma ◽  
Spontaneous Regression ◽  
Large Cell ◽  
Cell Lung Carcinoma ◽  
Large Cell Lung Carcinoma

scholarly journals Cancer-associated Retinopathy with Neuroendocrine Combined Large-cell Lung Carcinoma and Adenocarcinoma

2019 ◽  
Vol 58 (22) ◽  
pp. 3289-3294 ◽  
Author(s):  
Kyoko Yagyu ◽  
Takahiro Ueda ◽  
Atsushi Miyamoto ◽  
Riki Uenishi ◽  
Haruhiko Matsushita ◽  
...  
Keyword(s):  
Lung Carcinoma ◽  
Large Cell ◽  
Cell Lung Carcinoma ◽  
Large Cell Lung Carcinoma ◽  
Cancer Associated Retinopathy

scholarly journals Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes

2019 ◽  
Vol 116 (44) ◽  
pp. 22300-22306 ◽  
Author(s):  
Sara Lázaro ◽  
Miriam Pérez-Crespo ◽  
Corina Lorz ◽  
Alejandra Bernardini ◽  
Marta Oteo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Carcinoma ◽  
Small Cell Lung Carcinoma ◽  
Large Cell ◽  
Small Cell ◽  
Imaging Method ◽  
Cancer Type ◽  
High Grade ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma

High-grade neuroendocrine lung malignancies (large-cell neuroendocrine cell carcinoma, LCNEC, and small-cell lung carcinoma, SCLC) are among the most deadly lung cancer conditions with no optimal clinical management. The biological relationships between SCLC and LCNEC are still largely unknown and a current matter of debate as growing molecular data reveal high heterogeneity with potential therapeutic consequences. Here we describe murine models of high-grade neuroendocrine lung carcinomas generated by the loss of 4 tumor suppressors. In an Rbl1-null background, deletion of Rb1, Pten, and Trp53 floxed alleles after Ad-CMVcre infection in a wide variety of lung epithelial cells produces LCNEC. Meanwhile, inactivation of these genes using Ad-K5cre in basal cells leads to the development of SCLC, thus differentially influencing the lung cancer type developed. So far, a defined model of LCNEC has not been reported. Molecular and transcriptomic analyses of both models revealed strong similarities to their human counterparts. In addition, a 68Ga-DOTATOC–based molecular-imaging method provides a tool for detection and monitoring the progression of the cancer. These data offer insight into the biology of SCLC and LCNEC, providing a useful framework for development of compounds and preclinical investigations in accurate immunocompetent models.

scholarly journals MINI01.09: Outcomes of Early Stage Large Cell Neuroendocrine Lung Carcinoma (LCNELC): A National Cancer Database (NCDB) Analysis

2016 ◽  
Vol 11 (11) ◽  
pp. S261-S262
Author(s):  
Lara Kujtan ◽  
Kevin F. Kennedy ◽  
Sashidhar Manthravadi ◽  
J Russell Davis ◽  
Janakiraman Subramanian
Keyword(s):  
Lung Carcinoma ◽  
Early Stage ◽  
Large Cell ◽  
National Cancer Database

scholarly journals Intramedullary Spinal Cord Metastasis of Large Cell Lung Carcinoma. A Case Report.

1994 ◽  
Vol 43 (4) ◽  
pp. 1216-1220
Author(s):  
Hirokazu Hashiguchi ◽  
Kenzo Ito ◽  
Shinichi Nakamitsu ◽  
Yuichi Okazaki ◽  
Fujio Matsubara ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Lung Carcinoma ◽  
Large Cell ◽  
Cell Lung Carcinoma ◽  
Intramedullary Spinal Cord ◽  
Large Cell Lung Carcinoma ◽  
Spinal Cord Metastasis ◽  
Intramedullary Spinal Cord Metastasis
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