scholarly journals MINI01.09: Outcomes of Early Stage Large Cell Neuroendocrine Lung Carcinoma (LCNELC): A National Cancer Database (NCDB) Analysis

2016 ◽  
Vol 11 (11) ◽  
pp. S261-S262
Author(s):  
Lara Kujtan ◽  
Kevin F. Kennedy ◽  
Sashidhar Manthravadi ◽  
J Russell Davis ◽  
Janakiraman Subramanian
Keyword(s):  
Lung Carcinoma ◽  
Early Stage ◽  
Large Cell ◽  
National Cancer Database

Predictors for chemotherapy in early stage small cell lung carcinoma (SCLC): A National Cancer Database (NCDB) analysis

Lung Cancer ◽  
2017 ◽  
Vol 113 ◽  
pp. 85-87 ◽  
Author(s):  
Zaheer Ahmed ◽  
Punita Grover ◽  
Kevin F. Kennedy ◽  
Ashiq Masood ◽  
J. Russell Davis ◽  
...  
Keyword(s):  
Lung Carcinoma ◽  
Early Stage ◽  
Small Cell Lung Carcinoma ◽  
Small Cell ◽  
National Cancer Database ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma

scholarly journals Stereotactic ablative body radiotherapy versus conventionally fractionated radiotherapy for early stage large cell neuroendocrine carcinoma of the lung

2020 ◽  
Vol 9 (3) ◽  
pp. LMT32
Author(s):  
Rodney E Wegner ◽  
Stephen Abel ◽  
Athanasios Colonias
Keyword(s):  
Neuroendocrine Carcinoma ◽  
Cox Regression ◽  
Early Stage ◽  
Large Cell ◽  
Large Cell Neuroendocrine Carcinoma ◽  
National Cancer Database ◽  
Fractionated Radiotherapy ◽  
Academic Center ◽  
Stereotactic Ablative Body Radiotherapy ◽  
Propensity Matching

Aim: Some patients with early stage large cell neuroendocrine carcinoma (LCNEC) of the lung are not surgical candidates and will be managed with radiotherapy. We used the national cancer database to identify predictors of stereotactic radiotherapy and compare outcomes. Materials & methods: We queried national cancer database for T1-2N0 LCNEC treated with radiation. Logistic regression and Cox regression identified predictors of stereotactic ablative body radiotherapy (SABR) and survival, respectively. Results: We identified 754 patients, with 238 (32%) treated with SABR. Predictors of SABR were distance to facility, no chemotherapy, academic center, T1 and recent year. After propensity matching, median survival was 34.7 months compared with 23.7 months in favor of SABR (p = 0.02). Conclusion: SABR for LCNEC has increased over time and was associated with improved survival.

Peripheral T-cell repertoire alterations are common and affect outcome in large cell neuroendocrine lung carcinoma

Pneumologie ◽  
2018 ◽  
Vol 72 (S 01) ◽  
pp. S53-S54
Author(s):  
P Christopoulos ◽  
M Schneider ◽  
F Bozorgmehr ◽  
W Engel-Riedel ◽  
C Kropf-Sanchen ◽  
...  
Keyword(s):  
T Cell ◽  
Lung Carcinoma ◽  
Large Cell ◽  
T Cell Repertoire ◽  
Cell Repertoire
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