scholarly journals Relación entre ácidos grasos omega-3/omega-6 presentes en la dieta y enfermedad inflamatoria intestinal: Scoping review

2019 ◽  
Vol 23 (2) ◽  
pp. 92
Author(s):  
Ana Gutierrez-Hervás ◽  
Sofía García-Sanjuán ◽  
Sandra Gil-Varela ◽  
Ángela Sanjuán-Quiles

Introducción: La enfermedad inflamatoria intestinal (EII) incluye a la colitis ulcerosa (CU) y la enfermedad de Crohn (EC). Se cree que las grasas dietéticas pueden influir en su desarrollo. Objetivo: Analizar cómo se relaciona el contenido de omega-3 y omega-6 presentes en la dieta de forma natural con el proceso de la EII, tanto en su aparición como en su periodo de remisión. Material y métodos: Fuentes de datos: Se realizaron la búsqueda en las bases de datos Scopus y PubMed. Criterios de elegibilidad: Se incluyeron los estudios publicados entre 2007 y 2017, en español e inglés, diseño cuantitativo y cualitativo sobre el tema de estudio. Se excluyeron los estudios sobre fármacos o suplementos, animales y dieta en otras patologías. Evaluación de los estudios: Los estudios fueron evaluados a través de la Guía CASPe y los objetivos propios del diseño de scoping review.Resultados: Un total de 14 artículos fueron incluidos. Conclusiones: Hay evidencia de que el consumo de omega-3 y omega-6 puede influir en el desarrollo de la EII. Aunque no existen recomendaciones dietéticas definidas para las personas con EII, sería fundamental crear una guía de alimentación para el control de esta patología.

2020 ◽  
Vol 9 (7) ◽  
pp. e334974037
Author(s):  
Graciele Araújo de Oliveira Caetano ◽  
Angela Aparecida da Fonseca ◽  
Cibelle Borges Figueiredo

Um fator diferencial na produção de bovinos é a compreensão da contribuição individual dos ácidos graxos e do papel dos lipídeos nos ruminantes, tanto na forma de análise (ácido graxo ou extrato etéreo), conceitos relacionados às características de ômega 3, ômega 6 e ácido linoleico conjugado na bio-hidrogenação, no metabolismo pós-absorção, bem como no conteúdo e composição dos ácidos graxos em relação à matéria seca dos alimentos. Sabe-se que diversos fatores podem afetar o teor, digestibilidade e degradabilidade das fibras presente na forragem, e o mesmo ocorre com os lipídeos. As diferenças entre os valores dos compostos presentes nos lipídeos podem ocorrer dependendo do ambiente, região do país ou fase de colheita e por isso, torna-se importante obter a análise da composição de ácidos graxos dos alimentos lipídicos, para que dessa maneira seja possível otimizar a utilização deste nutriente na dieta de animais ruminantes. Sendo assim, a proposta dessa revisão será trazer a discussão sobre o tema e abordar um entendimento sobre o conteúdo e composição de ácidos graxos dos ingredientes que compõem a dieta dos animais ruminantes, com ênfase na influência exercida no desempenho produtivo, imunonutrição, e no produto final (carne ou leite).


BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e029554 ◽  
Author(s):  
Lee Hooper ◽  
Asmaa Abdelhamid ◽  
Julii Brainard ◽  
Katherine H O Deane ◽  
Fujian Song

ObjectiveTo create a database of long-term randomised controlled trials (RCTs) comparing higher with lower omega-3, omega-6 or total polyunsaturated fatty acid (PUFA), regardless of reported outcomes, and to develop methods to assess effects of increasing omega-6, alpha-linolenic acid (ALA), long-chain omega-3 (LCn3) and total PUFA on health outcomes.DesignSystematic review search, methodology and meta-analyses.Data sourcesMedline, Embase, CENTRAL, WHO International Clinical Trials Registry Platform, Clinicaltrials.gov and trials in relevant systematic reviews.Eligibility criteriaRCTs of ≥24 weeks' duration assessing effects of increasing ALA, LCn3, omega-6 or total PUFAs, regardless of outcomes reported.Data synthesisMethods included random-effects meta-analyses and sensitivity analyses. Funnel plots were examined, and subgrouping assessed effects of intervention type, replacement, baseline diabetes risk and use of diabetic medications, trial duration and dose. Quality of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE).ResultsElectronic searches generated 37 810 hits, de-duplicated to 19 772 titles and abstracts. We assessed 2155 full-text papers, conference abstracts and trials registry entries independently in duplicate. Included studies were grouped into 363 RCTs comparing higher with lower omega-3, omega-6 and/or total PUFA intake of at least 6 months’ duration—the Database.Of these 363 included RCTs, 216 RCTs were included in at least one of our reviews of health outcomes, data extracted and risk of bias assessed in duplicate. Ninety five RCTs were included in the Database but not included in our current reviews. Of these 311 completed trials, 27 altered ALA intake, 221 altered LCn3 intake and 16 trials altered omega-3 intake without specifying whether ALA or LCn3. Forty one trials altered omega-6 and 59 total PUFA.The remaining 52 trials are ongoing though 13 (25%) appear to be outstanding, or constitute missing data.ConclusionsThis extensive database of trials is available to allow assessment of further health outcomes.


2018 ◽  
Vol 42 (4) ◽  
Author(s):  
Yusti Pujiawati ◽  
Lilis Khotijah ◽  
Asep Sudarman ◽  
Indah Wijayanti

This study was conducted to compare the effect of different ratio of omega-3:omega-6 in total mix ration to blood metabolites and reproductive performance of ewes. A total of 25 young ewes were randomly assigned to five experimental groups and five replications : R0 (without omega-3:omega-6), R1 (omega-3:omega-6 1:8), R2 (omega-3:omega-6 1:6), R3 (omega-3:omega-6 1:3), R4 (omega-3:omega-6 1:2). The parameters measured were feed intake, productive performance, blood glucose and cholesterol pre-mating period. Parameters of characteristic estrous measured were onset of estrous, length of estrous and estrous response. The result showed that ratio of omega-3 and omega-6 1:2 have a greatest daily weight gain and feed efficiency. Ratio of omega-3 and omega-6 1:2 have blood glucose lowest, but highest blood cholesterol. Addition of omega-3 cause to delays onset of estrous. The conclusion is greatest length of estrous, estrous response and pregnacy rate on ratio of omega-3 and omega-6 1:2 in ration.


2007 ◽  
pp. 37-50
Author(s):  
K Mahomed ◽  
MA Williams ◽  
IB King ◽  
S Mudzamiri ◽  
GB Woelk

We sought to examine the association between maternal erythrocyte omega-3, omega-6 and trans fatty acids and risk of preeclampsia. We conducted a case-control study of 170 women with proteinuric, pregnancy-induced hypertension and 185 normotensive pregnant women who delivered at Harare Maternity Hospital, Harare, Zimbabwe. We measured erythrocyte omega-3, omega-6 and trans fatty acid as the percentage of total fatty acids using gas chromatography. After multivariate adjustment for confounding factors, women in the highest quartile group for total omega-3 fatty acids compared with women in the lowest quartile experienced a 14% reduction in risk of preeclampsia (odds ratio 0.86, 95% confidence interval 0.45 to 1.63). For total omega-6 fatty acids the odds ratio was 0.46 (95% confidence interval 0.23 to 0.92), although there was suggestion of a slight increase in risk of preeclampsia associated with high levels of arachidonic acid. Among women in the highest quartile for arachidonic acid the odds ratio was 1.29 (95% confidence interval 0.66 to 2.54). A strong statistically significant positive association of diunsaturated fatty acids with a trans double bond with risk of preeclampsia was observed. Women in the upper quartile of 9-cis 12-trans octadecanoic acid (C(18:2n6ct)) compared with those in the lowest quartile experienced a 3-fold higher risk of preeclampsia (odds ratio = 3.02, 95% confidence interval 1.41 to 6.45). Among women in the highest quartile for 9-trans 12-cis octadecanoic acid (C(18:2n6tc)) the odds ratio was 3.32 (95% confidence interval 1.55 to 7.13). Monounsaturated trans fatty acids were also positively associated with the risk of preeclampsia, although of much reduced magnitude. We observed a strong positive association of trans fatty acids, particularly diunsaturated trans fatty acids, with the risk of preeclampsia. We found little support for the hypothesized inverse association between omega-3 fatty acids and preeclampsia risk in this population. Polyunsaturated fatty acids, particularly omega-3 fatty acids, were comparatively lower in Zimbabwean than among US pregnant women. Given the limited inter-person variation in omega-3 fatty acids among Zimbabwean women, our sample size may be too small to adequately assess the relation in this population.


2013 ◽  
Vol 144 (5) ◽  
pp. S-837 ◽  
Author(s):  
David Val-Laillet ◽  
Paul Meurice ◽  
Jean-Paul Lalles ◽  
Charles-Henri Malbert
Keyword(s):  
Omega 3 ◽  
Omega 6 ◽  

2018 ◽  
Vol 9 (2) ◽  
pp. 418-433 ◽  
Author(s):  
Wan Maznah Wan Ishak ◽  
Haliza Katas ◽  
Ng Pei Yuen ◽  
Maizaton Atmadini Abdullah ◽  
Mohd Hanif Zulfakar

2013 ◽  
Vol 9 (18) ◽  
pp. 908-911 ◽  
Author(s):  
Yadla Phani Kumar ◽  
◽  
G Sri Shanmukha Srinivas ◽  
Yadu Mitravinda E ◽  
Lalitha Malla ◽  
...  
Keyword(s):  
Omega 3 ◽  
Omega 6 ◽  

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