COMBINED INCREASES IN MUSCLE-STRENGTHENING ACTIVITY FREQUENCY AND PROTEIN INTAKE REVEAL GRADED RELATIONSHIP WITH FAT-FREE MASS PERCENTAGE IN U.S. ADULTS, NHANES (1999-2004)

2015 ◽  
pp. 1-8
Author(s):  
J.M. KURKA ◽  
J. VEZINA ◽  
D.D. BROWN ◽  
J. SCHUMACHER ◽  
R.W. CULLEN ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Protein Intake ◽  
The United States ◽  
Fat Free Mass ◽  
Self Report ◽  
Linear Regression Models ◽  
Mass Percentage ◽  
Muscle Strengthening ◽  
Age Related ◽  
Males And Females

Background: Age-related loss of muscle mass and related ailments are of concern due to associations with disabilities and morbidity as well as constituting a substantial healthcare burden. Muscle-strengthening activities and adequate protein ingestion are recommended for all-age adults in an effort to stave off age-related muscle atrophy. Muscle building abilities decline with age but most research focuses on muscle wasting in the elderly. Objectives: To examine the independent and combined associations of protein intake (g∙kg-1∙day-1) and muscle-strengthening frequency (times∙week-1, MSF) on fat-free mass percentage (FFM%). Design Setting and Participants: This cross-sectional analysis of a population-based sample with data from the non-institutionalized persons in the United States participating in the National Health and Nutrition Examination Survey (cycles 1999-2000, 2001-2002, 2003-2004) consisted of male (n=2,499) and female (n=2,373) participants 20-49 years of age for analyses. Measurements: MSF was determined by self-report and protein intake was calculated from a 24-hour recall. Differences in FFM% from bioelectrical impedance analysis was estimated using multiple linear regression models controlling for education, race-ethnicity, standing height, and total Caloric intake. Results: One unit increase in MSF or protein intake (β-coefficient, ±SE) was associated with significantly more FFM% in males (0.6±0.1%; 3.5±0.4%) and females (0.4±0.1%; 5.9±0.4%). Independent of protein intake, males and females with MSF=0 had mean ±SE FFM% of 74.4±0.4 and 60.7±0.3, respectively, while mean ±SE FFM% of males and females who met the recommendation of ≥2 times per week were 77.9±0.5 and 63.0±0.4. Independent of MSF, males and females with protein intakes below the recommended dietary allowance (RDA) of 0.8 g∙kg-1∙day-1 had mean ±SE FFM% of 74.0±0.6 and 58.2±0.6, respectively, while mean ±SE FFM% of those whose intakes exceeded the recommendation were 75.6±0.4 and 62.0±0.4. The subgroup with the highest mean ±SE FFM% (80.9 ±0.73) comprised males with MSF ≥2 times per week who also consumed >1.4 g∙kg-1∙day-1. Conclusion: The MSF-protein intake dose relationship with FFM% suggests that performing muscle-strengthening activities >2 times per week while consuming protein above the RDA may result in more fat-free mass and slow age-related losses of muscle mass.

scholarly journals Effects of Reallocating Time Spent in Different Physical Activity Intensities on Sarcopenia Risk in Older Adults: An Isotemporal Substitution Analysis

Biology ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 111
Author(s):  
Jort Veen ◽  
Diego Montiel-Rojas ◽  
Fawzi Kadi ◽  
Andreas Nilsson
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Protein Intake ◽  
Handgrip Strength ◽  
Community Dwelling ◽  
Self Report ◽  
Linear Regression Models ◽  
Age Related ◽  
Muscle Health ◽  
The Impact

The role of daily time spent sedentary and in different intensities of physical activity (PA) for the maintenance of muscle health currently remains unclear. Therefore, we investigated the impact of reallocating time spent in different PA intensities on sarcopenia risk in older adults, while considering PA type (muscle strengthening activities, MSA) and protein intake. In a sample of 235 community-dwelling older adults (65–70 years), a sarcopenia risk score (SRS) was created based on muscle mass assessed by bioimpedance, together with handgrip strength and performance on the five times sit-to-stand (5-STS) test assessed by standardized procedures. Time spent in light-intensity PA (LPA), moderate-to-vigorous PA (MVPA), and being sedentary was assessed by accelerometry, and PA type (MSA) by self-report. Linear regression models based on isotemporal substitution were employed. Reallocating sedentary time to at least LPA was significantly (p < 0.05) related to a lower SRS, which remained evident after adjustment by PA type (MSA) and protein intake. Similarly, reallocating time in LPA by MVPA was related to a significantly (p < 0.05) lower SRS. Our results emphasize the importance of displacing sedentary behaviours for more active pursuits, where PA of even light intensities may alleviate age-related deteriorations of muscle health in older adults.

scholarly journals Location, Location, Location: The Role of Objective Neighborhood Characteristics for Perceptions of Control

Gerontology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Johanna Drewelies ◽  
Peter Eibich ◽  
Sandra Düzel ◽  
Simone Kühn ◽  
Christian Krekel ◽  
...  
Keyword(s):  
Internal Control ◽  
Reference Model ◽  
Self Report ◽  
Control Beliefs ◽  
External Control ◽  
Neighborhood Characteristics ◽  
Linear Regression Models ◽  
Residential Areas ◽  
Age Related ◽  
Self Report Data

<b><i>Introduction:</i></b> Control beliefs can protect against age-related declines in functioning. It is unclear whether neighborhood characteristics shape how much control people perceive over their life. This article studies associations of neighborhood characteristics with control beliefs of residents of a diverse metropolitan area (Berlin, Germany). <b><i>Methods:</i></b> We combine self-report data about perceptions of control obtained from participants in the Berlin Aging Study II (<i>N</i> = 507, 60–87 years, 51% women) with multisource geo-referenced indicators of neighborhood characteristics using linear regression models. <b><i>Results:</i></b> Findings indicate that objective neighborhood characteristics (i.e., unemployment rate) are indeed tied to perceptions of control, in particular, how much control participants feel others have over their lives. Including neighborhood characteristics in part doubled the amount of explained variance compared with a reference model covarying for demographic characteristics only (from <i>R</i><sup>2</sup> = 0.017 to <i>R</i><sup>2</sup> = 0.030 for internal control beliefs; <i>R</i><sup>2</sup> = 0.056 to <i>R</i><sup>2</sup> = 0.102 for external control beliefs in chance; <i>R</i><sup>2</sup> = 0.006 to <i>R</i><sup>2</sup> = 0.030 for external control beliefs in powerful others). <b><i>Discussion/Conclusion:</i></b> Findings highlight the importance of access to neighborhood resources for control beliefs across old age and can inform interventions to build up neighborhood characteristics which might be especially helpful in residential areas with high unemployment.

scholarly journals Association of Protein Intake in Three Meals with Muscle Mass in Healthy Young Subjects: A Cross-Sectional Study

Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 612 ◽  
Author(s):  
Jun Yasuda ◽  
Mai Asako ◽  
Takuma Arimitsu ◽  
Satoshi Fujita
Keyword(s):  
Muscle Mass ◽  
Protein Intake ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Cross Sectional Study ◽  
Fat Free Mass ◽  
Intake Rate ◽  
Young Population ◽  
Cross Sectional ◽  
Young Subjects

Protein intake of >0.24 g/kg of body weight (BW) at a single meal is necessary to maximize muscle protein synthesis in a young population. However, the association between the protein intake rate for three meals and muscle mass in the young population has not been evaluated. We hypothesized that a protein intake of >0.24 g/kg BW at all three meals is effective for maintaining muscle mass. Therefore, we cross-sectionally examined the association between protein intake at all three meals with muscle mass in 266 healthy young subjects (aged 21.4 ± 2.4 years). Subjects were divided into the AP group, which achieved protein intake >0.24 g/kg BW at all three meals; and the NP group, which did not. We calculated total fat-free mass (FFM) and appendicular fat-free mass (AppFFM) with dual-energy X-ray absorptiometry, and the percentage of total FFM (TotalFFM%) and appendicular FFM (AppFFM%) were calculated as the percentage of BW (%BW). We demonstrated that TotalFFM% (77.0 ± 0.5 vs. 75.2 ± 0.4%, p = 0.008) and AppFFM% (34.7 ± 0.3 vs. 34.1 ± 0.2%, p = 0.058) were higher in the AP than in the NP group. This finding suggests that achieving protein intake of >0.24 g/kg BW at all three meals is important for muscle mass maintenance in young populations.

Muscle Function in Saudi Children and Adolescents: Relationship to Anthropometric Characteristics during Growth

2007 ◽  
Vol 19 (3) ◽  
pp. 319-333 ◽  
Author(s):  
Khalid S. Almuzaini
Keyword(s):  
Children And Adolescents ◽  
Anaerobic Power ◽  
Age Groups ◽  
Fat Free Mass ◽  
Power Indices ◽  
Isokinetic Strength ◽  
Linear Regression Models ◽  
Age Related ◽  
Wide Range ◽  
Anthropometric Characteristics

The main purpose of the present study was to determine isokinetic strength and endurance, isometric strength, and anaerobic power for untrained healthy Saudi children and adolescents. The secondary purpose was to evaluate the effects of age in relation to anthropometric characteristics on strength and anaerobic performances. Forty-four (untrained) 11- to 19-year-old boys were grouped by age: 11-13 years, 14–16 years, and 17–19 years. All participants underwent anthropometric measurements, a flexibility test, a vertical jump test, a grip strength test, isokinetic strength measurements (Cybex Norm), and a Wingate anaerobic power test. Oneway ANOVA results indicated age-related increases in muscle strength and power. High correlation coefficients that were found among age and strength and anaerobic power indices almost disappeared when fat-free mass (FFM) was controlled for, indicating that the amount of variance in these indices that was explained by age is mostly shared by FFM. In addition, stepwise linear regression models indicated that FFM was the main predictor of strength and power performances. Thus, FFM was the best scaling variable for body size when comparing these age groups of Saudis. Until wide-range normal representative values for isokinetic strength and anaerobic power for Saudi children and adolescents are available, the present study’s results can serve as a reference for these indices.

scholarly journals Protein Intake, Distribution and Food Sources in Adults of Advanced Age: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)

Proceedings ◽  
2019 ◽  
Vol 37 (1) ◽  
pp. 10
Author(s):  
Ram ◽  
Kerse ◽  
Moyes ◽  
Rolleston ◽  
Wham
Keyword(s):  
Cohort Study ◽  
New Zealand ◽  
Muscle Mass ◽  
Protein Intake ◽  
Advanced Age ◽  
Food Sources ◽  
Age Related

Protein intake and its food sources is important to prevent age related loss of muscle mass andstrength. [...]

DIETARY PROTEIN TO MAINTAIN MUSCLE MASS IN AGING: A CASE FOR PER-MEAL PROTEIN RECOMMENDATIONS

2016 ◽  
pp. 1-10
Author(s):  
C.H. MURPHY ◽  
S.Y. OIKAWA ◽  
S.M. PHILLIPS
Keyword(s):  
Muscle Mass ◽  
Dietary Protein ◽  
Protein Intake ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Dietary Advice ◽  
Age Related ◽  
Meal Protein ◽  
Single Meal ◽  
And Function

It is well accepted that daily protein intake is an important dietary consideration to limit and treat age-related declines in muscle mass, strength, and function. Furthermore, we propose that there is a growing appreciation for the need to consider protein intake on a per-meal basis rather than simply focusing on the total daily protein intake. The existence of a saturable dose-response relationship between muscle protein synthesis (MPS) and the quantity of protein consumed in a single meal/bolus provides the rationale for promoting an even/balanced pattern of daily protein intake. We hypothesize that a balanced/even protein intake pattern with the ingestion a quantity of protein shown to optimally stimulate MPS at each meal may be an effective strategy to alleviate sarcopenic muscle loss. In this review we examine the available evidence supporting the influence of dietary protein intake pattern on muscle protein turnover, muscle mass, and muscle function. We present several practical considerations that, it is proposed, should be taken into account when translating a per-meal protein recommendation into dietary advice for older adults.

Sarcopenia—definitions and epidemiology

2017 ◽  
pp. 409-414
Author(s):  
José A. Morais
Keyword(s):  
Older Adults ◽  
Skeletal Muscle ◽  
Muscle Mass ◽  
Protein Intake ◽  
Skeletal Muscle Mass ◽  
Handgrip Strength ◽  
Resistance Exercise Training ◽  
Adverse Health Outcomes ◽  
Age Related ◽  
Underlying Mechanisms

Sarcopenia is a progressive and inevitable loss of skeletal muscle mass and strength associated with ageing that places older adults at high risk for adverse health outcomes. Up to of 15% of older adults suffer negative healthcare consequences because of sarcopenia. Furthermore, it is responsible for two to four times greater risk of disability. Expert groups have proposed clinical oriented criteria based on gait speed <0.8 m/s and low handgrip strength before performing muscle mass assessment. Multiple aetiologies are implicated in the development of sarcopenia including age-related, lifestyle, neurodegeneration, hormonal, and inflammation factors. Resistance exercise training and higher than recommended protein intake are two accessible means to counteract sarcopenia. Hormonal interventions, despite amelioration in muscle and fat masses, have not led to significant gains in function. Sarcopenia shares many features with frailty and can be considered as one of its underlying mechanisms.

scholarly journals 977. The Prevalence and Burden of Non-AIDS Co-Morbidities in Women with or At-risk for HIV Infection in the United States

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S36-S36
Author(s):  
Lauren F Collins ◽  
Anandi N Sheth ◽  
C Christina Mehta ◽  
Elizabeth T Golub ◽  
Phyllis C Tien ◽  
...  
Keyword(s):  
At Risk ◽  
Clinical Care ◽  
Laboratory Data ◽  
The United States ◽  
Self Report ◽  
Age Related ◽  
Persons Living With Hiv ◽  
Hiv Serostatus ◽  
Hiv Women

Abstract Background Age-related non-AIDS comorbidities (NACM) increasingly account for morbidity and mortality in persons living with HIV. The burden of NACM and its association with HIV is poorly described in women. Methods We analyzed data from HIV+ and at-risk HIV− participants who were followed in the Women’s Interagency HIV Study (WIHS) after 2009 (when >80% of participants used antiretroviral therapy). The prevalence of each NACM (defined by a combination of self-report, clinical measurements, and laboratory data) and the number of NACM were summarized at a most recent follow-up visit and were compared by age and HIV serostatus using unadjusted linear regression models. Results There were 3232 women (2309 HIV+, 923 HIV–) with a median follow-up of 15.3 years. The median age was 50 years, 65% were black, 38% currently smoked, 71% had ever used illicit drugs, 50% had annual income < $12,000, and median body mass index was 30 kg/m2. HIV+ women had a median CD4 count of 618 cells/mm3 and 66% had HIV viral suppression. Among 10 NACM evaluated, the following were more prevalent in HIV+ vs. HIV– women (all P < 0.01): psychiatric illness (57%/48%), liver disease (45%/26%), hyperlipidemia (40%/35%), bone disease (40%/33%), chronic kidney disease (15%/7%), and non-AIDS cancer (11%/7%). There was little difference in the prevalence of hypertension (66%/64%), lung disease (41%/43%), diabetes (22%/24%), and cardiovascular disease (19%/19%). Mean number of NACM was higher in HIV+ vs. HIV– women (3.6 vs. 3.0, P < 0.0001). Regardless of HIV serostatus, NACM burden significantly increased with age (P < 0.0001). Compared with women aged <40 of the same HIV serostatus, the estimated mean difference in NACM (HIV+/HIV–) for those 40–49, 50–59, ≥60 years was 1.1/0.7, 2.3/2.3, and 3.6/3.2, respectively (P < 0.0001 for all). Within-age-group comparisons revealed significantly greater NACM burden in HIV+ vs. HIV− women aged 40–49 years (P < 0.0001) and ≥60 years (P = 0.003), but not in those aged <40 or 50–59 years (HIV*age interaction P = 0.02) (figure). Conclusion NACM burden was high in both HIV+ and at-risk HIV– women, but higher in HIV+ women overall and in certain age groups. Accumulation of NACM has complex implications for clinical care, medication management, and healthcare screening that must be further examined in this population. Disclosures Anandi N. Sheth, MD, MS, Gilead Sciences, Inc.: Research Grant.

scholarly journals EFFECTS OF PROGRAMMED FITNESS EXERCISE ON BODY COMPOSITION AMONG PRE-SCHOOL CHILDREN

2018 ◽  
Vol 16 (1) ◽  
pp. 047
Author(s):  
Predrag Bićanin ◽  
Saša Milenković ◽  
Dragan Radovanović ◽  
Aco Gajević ◽  
Jelena Ivanović
Keyword(s):  
Body Composition ◽  
Muscle Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Fat Free Mass ◽  
Control Group ◽  
Body Fat Mass ◽  
Mass Percentage ◽  
Fitness Clubs ◽  
Experimental Group

This research included a sample of 79 pre-school boys aged 6 and 7 with 40 of them in the experimental group and 39 in the control group. Their current state of body composition was studied, as well as their relations after a 6-month fitness treatment that the experimental group of participants was involved in, in order to analyze its effects. The experimental group had two classes per week, in addition to regular programmed activities as part of the children’s sport school (three times per week), and as part of 48 of additional, six-month training lessons of exercising in sport (fitness) clubs. The following variables have been used to evaluate body composition with the application of bio-electric impedance In Body 230 such as: muscle mass, percentage of muscle mass, body fat mass, percentage of body fat mass, fat free mass, percentage of fat free mass. Although small to moderate effects were obtained by the double mixed ANOVA, the results show the experimental group’s achievements as significantly higher than those of the control group. Furthermore, with individual eta coefficient findings in comparison with each group measurements, it is clear that the value of the obtained effects is different between groups to the benefit of the experimental group. Permanent implementation of the proposed programme could contribute to an improvement on the studied body composition variables which can result in the better health status of children in future.    

scholarly journals Associations Between Glucose Tolerance, Insulin Secretion, Muscle and Fat Mass in Cystic Fibrosis

2021 ◽  
Vol 14 ◽  
pp. 117955142110382
Author(s):  
Bibi Uhre Nielsen ◽  
Daniel Faurholt-Jepsen ◽  
Peter Sandor Oturai ◽  
Tavs Qvist ◽  
Rikke Krogh-Madsen ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Insulin Secretion ◽  
Glucose Tolerance ◽  
Muscle Mass ◽  
Fat Mass ◽  
Plasma Glucose ◽  
Fat Free Mass ◽  
Oral Glucose ◽  
Linear Regression Models ◽  
Fat Mass Index

Background: A frequent comorbidity in cystic fibrosis (CF) is CF related diabetes (CFRD) caused by a gradual decline in insulin secretion. The reduction in the anabolic hormone, insulin, might explain the weight loss that precedes onset of CFRD. We investigated the association between muscle and fat mass in relation to glucose tolerance and insulin function. Methods: In a cross-sectional study with CF patients (⩾18 years), we conducted an oral glucose tolerance test and dual energy X-ray absorptiometry scan (DXA). Based on plasma glucose, glucose tolerance was defined as normal (NGT): 1-hour <11.1 mmol/L and 2-hour <7.8 mmol/L, impaired (IGT): 2-hour ⩾7.8 and <11.1 mmol/L or CFRD: 2-hour ⩾11.1 mmol/L. Insulin resistance (HOMA-IR) was derived from fasting levels of plasma glucose and plasma insulin, and fat-free and fat mass index (kg/m2) from DXA. Associations were evaluated using linear regression models adjusted for age, sex, and pancreas insufficiency. Results: Among 79 CF patients with exocrine pancreas insufficiency, impairment of glucose tolerance corresponded to reduced insulin secretion. In the IGT group the fat-free mass index (FFMI) was 1.2 kg/m2 (95% CI: [−2.3, −0.03] kg/m2, P = .044) lower compared to the NGT group. FFMI increased insignificantly by 0.4 kg/m2 (95% CI: [−0.6, 1.5] kg/m2, P = .422) among the insulin-treated CFRD group compared to IGT. Fat mass index (FMI) was not different between groups but tended to decrease with glucose tolerance impairment. For each 100 pmol/L increase in fasting insulin FFMI increased by 1.77 kg/m2 (95% CI: [0.21, 3.33] kg/m2/pmol/L/100) and FMI increased by 6.15 kg/m2 (95% CI: [3.87, 8.44] kg/m2/pmol/L/100). In multivariate analyses, HOMA-IR was positively associated with FFMI (β = 0.5 kg/m2/HOMA-IR, 95% CI: [0.08, 0.92] kg/m2/HOMA-IR, P = .021) and FMI (β = 1.5 kg/m2/HOMA-IR, 95% CI: [0.87, 2.15] kg/m2/HOMA-IR, P < .001). Conclusions: Muscle mass was significantly lower among participants with impaired glucose tolerance (IGT), while muscle mass was normalized among those treated with insulin.

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