Bioactive compound-producing symbiotic bacteria from marine sponge species: cultural, gene retrieval and metagenomic studies

2006 ◽  
Author(s):  
◽  
T. Kim
Author(s):  
Joicy Abraham ◽  
Mahija S. P ◽  
Jency George ◽  
Manjusha W. A

Marine sponges are rich sources of pharmacological active compound. Marine sponge, Dendrilla membranosa was collected from the Vizhingam coast. The sponge extract was tested against eight human bacterial pathogens. The bioactive compounds present in marine sponge were determined by GC-MS analysis. The cytotoxic effect of the sponge was evaluated by using MTT assay. The extracts showed potent anti-bacterial activity against Staphylococcus aureus, Bacillus subtilis, Streptococcus pyogens. The bioactive compound present in marine sponge was identified by GC-MS analysis and the compounds are ethane, butane, formate pentane, Alpha d-galactopyranoside, 2-Ethylhexyl2-ethylhexanoate, Hexahydro hexitol, Styrene, Alpha-d glucopyranoside 1-pentyl-2-proppyl-1-octene, nonadecane, 1,2-benzenedicarboxylic acid, bis-2, Octanoic acid. The test material showed none cytotoxic response to fibroblasts cells. The results of present investigation revealed that, Dendrilla membranosa is a potential source of novel anticancer and antibacterial leads.


2019 ◽  
Vol 10 ◽  
Author(s):  
Marinella Silva Laport ◽  
Ulisses Pinheiro ◽  
Caio Tavora Coelho da Costa Rachid

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
VM Kutluay ◽  
B Konuklugil ◽  
I Saracoglu

2007 ◽  
Vol 93 (3) ◽  
pp. 241-248 ◽  
Author(s):  
Haitao Zhang ◽  
Wei Zhang ◽  
Yan Jin ◽  
Meifang Jin ◽  
Xingju Yu

2017 ◽  
Vol 24 (1) ◽  
pp. 6-15 ◽  
Author(s):  
Nia M. Kurnia ◽  
Agustinus R. Uria ◽  
Yudi Kusnadi ◽  
Lidia Dinawati ◽  
Dewi S. Zilda ◽  
...  

Author(s):  
Gilles Barnathan ◽  
Joseph Miralles ◽  
Jean-Michel Njinkoue ◽  
Alfonso Mangoni ◽  
Ernesto Fattorusso ◽  
...  

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