Effect of dietary nano-selenium on stress indicators, immune response, and DNA damage in broiler subjected to different stocking density

2021 ◽  
Author(s):  
Ö. Sevim* ◽  
U. Ahsan ◽  
O. Tatlı ◽  
E. Kuter ◽  
E. Karimiyan Khamseh ◽  
...  
Keyword(s):  
Immune Response ◽  
Dna Damage ◽  
Stocking Density ◽  
Stress Indicators

scholarly journals Diverse immune response of DNA damage repair-deficient tumors

2021 ◽  
Vol 2 (5) ◽  
pp. 100276
Author(s):  
Tao Qing ◽  
Tomi Jun ◽  
Katherine E. Lindblad ◽  
Amaia Lujambio ◽  
Michal Marczyk ◽  
...  
Keyword(s):  
Immune Response ◽  
Dna Damage ◽  
Dna Damage Repair ◽  
Damage Repair

scholarly journals DNA Damage Response and Oxidative Stress in Systemic Autoimmunity

2019 ◽  
Vol 21 (1) ◽  
pp. 55 ◽  
Author(s):  
Vassilis L. Souliotis ◽  
Nikolaos I. Vlachogiannis ◽  
Maria Pappa ◽  
Alexandra Argyriou ◽  
Panagiotis A. Ntouros ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Immune Response ◽  
Dna Damage ◽  
Autoimmune Diseases ◽  
Dna Damage Response ◽  
Lupus Erythematosus ◽  
Mononuclear Cells ◽  
Tissue Injury ◽  
Systemic Autoimmune Diseases ◽  
Damage Response

The DNA damage response and repair (DDR/R) network, a sum of hierarchically structured signaling pathways that recognize and repair DNA damage, and the immune response to endogenous and/or exogenous threats, act synergistically to enhance cellular defense. On the other hand, a deregulated interplay between these systems underlines inflammatory diseases including malignancies and chronic systemic autoimmune diseases, such as systemic lupus erythematosus, systemic sclerosis, and rheumatoid arthritis. Patients with these diseases are characterized by aberrant immune response to self-antigens with widespread production of autoantibodies and multiple-tissue injury, as well as by the presence of increased oxidative stress. Recent data demonstrate accumulation of endogenous DNA damage in peripheral blood mononuclear cells from these patients, which is related to (a) augmented DNA damage formation, at least partly due to the induction of oxidative stress, and (b) epigenetically regulated functional abnormalities of fundamental DNA repair mechanisms. Because endogenous DNA damage accumulation has serious consequences for cellular health, including genomic instability and enhancement of an aberrant immune response, these results can be exploited for understanding pathogenesis and progression of systemic autoimmune diseases, as well as for the development of new treatments.

Bacterial Genotoxins as the Interphase Between DNA Damage and Immune Response

2016 ◽  
pp. 1-20
Author(s):  
Océane C. B. Martin ◽  
Teresa Frisan ◽  
Boris Mihaljevic
Keyword(s):  
Immune Response ◽  
Dna Damage

Bacterial Genotoxins as the Interphase Between DNA Damage and Immune Response

2018 ◽  
pp. 383-402 ◽  
Author(s):  
Océane C. B. Martin ◽  
Teresa Frisan ◽  
Boris Mihaljevic
Keyword(s):  
Immune Response ◽  
Dna Damage

scholarly journals Effects of prebiotic, protein level, and stocking density on performance, immunity, and stress indicators of broilers

2012 ◽  
Vol 91 (2) ◽  
pp. 393-401 ◽  
Author(s):  
M. Houshmand ◽  
K. Azhar ◽  
I. Zulkifli ◽  
M.H. Bejo ◽  
A. Kamyab
Keyword(s):  
Protein Level ◽  
Stocking Density ◽  
Stress Indicators

Effects of stocking density and feed ration on growth and gene expression in the Senegalese sole (Solea senegalensis): Potential effects on the immune response

2010 ◽  
Vol 28 (2) ◽  
pp. 296-302 ◽  
Author(s):  
Emilio Salas-Leiton ◽  
Victoria Anguis ◽  
Beatriz Martín-Antonio ◽  
Diego Crespo ◽  
Josep V. Planas ◽  
...  
Keyword(s):  
Gene Expression ◽  
Immune Response ◽  
Stocking Density ◽  
Solea Senegalensis ◽  
Senegalese Sole

scholarly journals The importance of nutrition in alleviating high stocking density stress in poultry

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Esra Tuğçe Gül ◽  
Alpönder Yildiz ◽  
Osman Olgun
Keyword(s):  
Animal Welfare ◽  
Egg Production ◽  
Unit Area ◽  
Stocking Density ◽  
Meat Production ◽  
Negative Effects ◽  
Stress Indicators ◽  
And Performance ◽  
The Ideal

Abstract In recent decades, the number of birds reared per unit area has dramatically spiked to increase profitability in egg and meat production. However, nowadays, the increase in sensitivity to animal welfare and consumer demands brings along with it a raised interest in stocking density. Stocking density is defined either as the number of animals or body weight per unit area or as the area per animal. High stocking density, which is a stress factor, can be defined as an increase in the number of animals per unit area or a decrease in the area per animal. Stress caused by high stocking density negatively affects the bird’s physiology and performance as well as the quality of the product obtained. The ideal stocking density should be 9 laying hens, 35 kilogrammes for broilers, and 45 quails per square metre. Otherwise, one will observe stress indicators in birds reared in more than the recommended stocking density per unit area and, consequently, a decrease in bird growth, egg production, feed efficiency, and egg or meat quality. Apart from increasing the concentrations of amino acids such as lysine, methionine, tryptophan and arginine, minerals such as selenium and chromium, and vitamins such as C and E in the diet, the addition of additives such as probiotics, humates, phytophenol compounds, and propolis is also effective in reducing or eliminating these negative effects caused by high stocking density. As a result, regulations in the nutrition of animals are effective in reducing/preventing such negative effects, thus improving animal welfare and ensuring the maintenance of optimum yield.

Sign in / Sign up

Export Citation Format

Share Document