Urothelial Carcinoma of the Prostate: An Immunohistochemical Comparison with High Grade Prostatic Adenocarcinoma and Review of the Literature

1998 ◽  
Vol 9 (2) ◽  
pp. 141-154 ◽  
Author(s):  
John C. Cheville
2000 ◽  
Vol 13 (11) ◽  
pp. 1186-1191 ◽  
Author(s):  
Elizabeth M Genega ◽  
Brian Hutchinson ◽  
Victor E Reuter ◽  
Paul B Gaudin

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Kenichi Mori ◽  
Tadasuke Ando ◽  
Takeo Nomura ◽  
Fuminori Sato ◽  
Hiromitsu Mimata

Lymphoepithelioma-like carcinoma (LELC) in the bladder is uncommon with a reported incidence of 0.4%–1.3% of all bladder carcinomas. In Japan, some occurrences of LELC have been reported in the renal pelvis and ureter but only two in the bladder. A bladder tumor was identified in a 70-year-old man suffering from macroscopic hematuria for 2 months. Sections of the transurethral tumor resection showed invasive high-grade urothelial carcinoma. The patient was diagnosed with local invasive bladder tumor, and cystectomy with ileal conduit formation was performed. The final pathological evaluation was predominant LELC with urothelial carcinoma. We present a new case of LELC in the bladder and performed a review of all published cases of LELC in the urinary tract to obtain its characteristics and prognostic guide.


2005 ◽  
Vol 129 (5) ◽  
pp. 683-685 ◽  
Author(s):  
Antonio Lopez-Beltran ◽  
John N. Eble ◽  
David G. Bostwick

Abstract We report the clinical and pathologic features of 2 cases of pleomorphic giant cell carcinoma of the prostate. One case was found at autopsy in a 77-year-old man and was composed of high-grade prostatic adenocarcinoma with prominent anaplastic giant cells. The patient presented with metastases to multiple retroperitoneal lymph nodes, liver, and lumbar vertebrae. The second case occurred in a 45-year-old man who underwent transurethral resection of the prostate and was found to have high-grade prostatic adenocarcinoma with an extensive anaplastic giant cell component. The patient presented with distant metastases and died within 9 months. Both regular adenocarcinoma and anaplastic giant tumor cells displayed cytoplasmic immunoreactivity for prostate-specific antigen, prostatic acid phosphatase, and keratin AE1/AE3; in one case, scattered cells were also positive for chromogranin and epithelial membrane antigen. Pleomorphic giant cell carcinoma is a rare variant of prostatic adenocarcinoma with a poor prognosis that should be considered in the differential diagnosis of prostatic pleomorphic tumors.


CytoJournal ◽  
2010 ◽  
Vol 7 ◽  
pp. 18 ◽  
Author(s):  
Chetna N. Purohit ◽  
Marilyn M. Bui ◽  
Ardeshir Hakam

Osteoclast-rich undifferentiated carcinoma of urinary bladder (ORUCUB) is a very rare and an unusual variant of high-grade urothelial carcinoma. Here, we report an extraordinary case of metastatic ORUCUB, diagnosed by fine needle aspiration (FNA) biopsy, in a 74-year-old Hispanic male who presented with a palpable, tender left groin mass and a known previous history of high-grade carcinoma of urinary bladder and prostatic cancer. To the best of our knowledge, diagnosis of ORUCUB by FNA is the first case report in FNA cytology to be published to date. A review of the literature is emphasized on the cytological, histological and immunohistochemical features and differential diagnoses of giant cell tumor.


2007 ◽  
Vol 32 (9) ◽  
pp. 746-747 ◽  
Author(s):  
Linh Ho ◽  
Vicki Quan ◽  
Robert Henderson ◽  
John Seto

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