Discovery of a New Class of Synthetic Protein Kinase Inhibitors that Suppress Selective Aspects of Glial Activation and Protect Against β-Amyloid Induced Injury: A Foundation for Future Medicinal Chemistry Efforts Focused on Targeting Alzheimer's Disease Progression

2003 ◽  
Vol 20 (3) ◽  
pp. 411-424 ◽  
Author(s):  
D. Martin Watterson ◽  
Anastasia V. Velentza ◽  
Magdalena Zasadzki ◽  
Jeffrey M. Craft ◽  
Jacques Haiech ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Protein Kinase ◽  
Disease Progression ◽  
Medicinal Chemistry ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
Glial Activation ◽  
New Class ◽  
Synthetic Protein ◽  
Β Amyloid

ChemInform Abstract: Entry into a New Class of Protein Kinase Inhibitors by Pseudo Ring Design.

ChemInform ◽  
2008 ◽  
Vol 39 (27) ◽  
Author(s):  
Pascal Furet ◽  
Giorgio Caravatti ◽  
Vito Guagnano ◽  
Marc Lang ◽  
Thomas Meyer ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
New Class

scholarly journals Current progress, challenges and future prospects of indazoles as protein kinase inhibitors for the treatment of cancer

RSC Advances ◽  
2021 ◽  
Vol 11 (41) ◽  
pp. 25228-25257
Author(s):  
Nitin Tandon ◽  
Vijay Luxami ◽  
Divya Kant ◽  
Runjhun Tandon ◽  
Kamaldeep Paul
Keyword(s):  
Protein Kinase ◽  
Medicinal Chemistry ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
Future Prospects

The indazole core is an interesting pharmacophore due to its applications in medicinal chemistry.

Entry into a new class of protein kinase inhibitors by pseudo ring design

2008 ◽  
Vol 18 (3) ◽  
pp. 897-900 ◽  
Author(s):  
Pascal Furet ◽  
Giorgio Caravatti ◽  
Vito Guagnano ◽  
Marc Lang ◽  
Thomas Meyer ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
New Class

scholarly journals Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors.

1990 ◽  
Vol 265 (36) ◽  
pp. 22255-22261
Author(s):  
J F Geissler ◽  
P Traxler ◽  
U Regenass ◽  
B J Murray ◽  
J L Roesel ◽  
...  
Keyword(s):  
Biological Activity ◽  
Protein Kinase ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
Tyrosine Protein Kinase
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