Relationship Between Phalangeal Bone Density and Risk of Vertebral Fracture

2002 ◽  
Vol 5 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Misako Ohtsuka ◽  
Daniel Michaeli ◽  
Richard D. Wasnich
2009 ◽  
Vol 8 (7) ◽  
pp. 817-822 ◽  
Author(s):  
Tim D. Spector ◽  
Eugene V. Mccloskey ◽  
David V. Doyle ◽  
John A. Kanis

2010 ◽  
Vol 37 (7) ◽  
pp. 1473-1479 ◽  
Author(s):  
EDMUND K. LI ◽  
TRACY Y. ZHU ◽  
LAI-SHAN TAM ◽  
VIVIAN W. HUNG ◽  
JAMES F. GRIFFITH ◽  
...  

Objective.We assessed the relationship between vertebral fracture and bone microarchitecture in patients with systemic lupus erythematosus (SLE) on chronic corticosteroid therapy using high-resolution peripheral quantitative computed tomography (HR-pQCT).Methods.Fifty-nine Chinese women with SLE taking corticosteroid were selected to participate in a cross-sectional study. Vertebral fracture was confirmed semiquantitatively by lateral radiographs of the thoracic and lumbar spine. Density and microarchitecture at the distal radius were measured with HR-pQCT. Areal bone mineral density (aBMD) at hip and lumbar spine was measured by dual-energy x-ray absorptiometry (DEXA).Results.Twelve patients had vertebral fractures. The aBMD of spine or hip did not differ between those with and without vertebral fractures. Measures by HR-pQCT revealed that patients with vertebral fractures had significantly lower level of average bone density (p = 0.007), cortical bone density (p = 0.029), trabecular bone density (p = 0.024), trabecular bone volume to tissue volume (p = 0.023), and trabecular thickness (p = 0.011) than those without vertebral fractures. Independent explanatory variables associated with higher risk of vertebral fractures were older age (p = 0.013) and lower average cortical bone density (p = 0.029).Conclusion.Vertebral fracture in patients with SLE on chronic corticosteroid treatment was associated with alterations of bone density and microarchitectures measured by HR-pQCT and DEXA. However, alterations were more pronounced in measurements by HR-pQCT. Low cortical bone density and old age were significant predictors of vertebral fracture risk.


2000 ◽  
Vol 67 (4) ◽  
pp. 277-285 ◽  
Author(s):  
S. Wallach ◽  
S. Cohen ◽  
D. M. Reid ◽  
R. A. Hughes ◽  
D. J. Hosking ◽  
...  

Bone ◽  
2019 ◽  
Vol 121 ◽  
pp. 72-79 ◽  
Author(s):  
John T. Schousboe ◽  
Lisa M. Lix ◽  
Suzanne N. Morin ◽  
Sheldon Derkatch ◽  
Mark Bryanton ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A627-A628
Author(s):  
Stanley Wallach ◽  
Michael Maricic ◽  
Stanley Cohen ◽  
David M. Reid ◽  
Kathleen J. Bos

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