Bone Mineral Density and Broadband Ultrasound Attenuation with Estrogen Treatment of Postmenopausal Women

1998 ◽  
Vol 1 (1) ◽  
pp. 19-26 ◽  
Author(s):  
P. Balikian ◽  
K. Burbank ◽  
J. Houde ◽  
G. Crane ◽  
J. Nairus ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Broadband Ultrasound Attenuation ◽  
Estrogen Treatment ◽  
Mineral Density ◽  
Ultrasound Attenuation

Dependence of broadband ultrasound attenuation on the elastic anisotropy of trabecular bone

1998 ◽  
Vol 212 (3) ◽  
pp. 223-226 ◽  
Author(s):  
S-M Han ◽  
J-Y Rho
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Elastic Anisotropy ◽  
Quantitative Computed Tomography ◽  
Broadband Ultrasound Attenuation ◽  
Mineral Density ◽  
Ultrasound Attenuation ◽  
Ultrasonic Parameters

The effect of trabecular elastic anisotropy on broadband ultrasound attenuation (BUA) and bone mineral density (BMD) was investigated with human and bovine cubic cancellous bones. Ultrasonic parameters describing trabecular anisotropy were found from the three orthogonal ultrasound velocities. BMD was measured using quantitative computed tomography. Three elastic anisotropy ratios were compared to BUA in all three directions and to BMD. The combined effect of anisotropic characteristics and BMD was also correlated with BUA. The results showed that the anisotropy ratios were significantly related to BUA (p<0.05). There was, however, no correlation between BMD and the elastic anisotropy ratios. The combination of BMD and the anisotropy produced a significantly enhanced relationship with BUA.

scholarly journals Investigating the effect of strontium in bone mineral density measurements of trabecular bone mimicking phantoms using quantitative ultrasound

2021 ◽  
Author(s):  
Bisma Rizvi
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Broadband Ultrasound Attenuation ◽  
Mineral Density ◽  
Strontium Content ◽  
Gold Standard Method ◽  
Diagnosis Of Osteoporosis ◽  
X Ray ◽  
Ultrasound Attenuation

Dual-energy x-ray absorptiometry (DXA) is the current gold standard method used for the diagnosis of osteoporosis. However, it is well-established that the presence of strontium in bone could lead to significant error in measurement of bone mineral density (BMD) and diagnosis of osteoporosis using DXA. The objectives of this study are: (1) to develop novel bone-mimicking phantoms containing different concentrations of strontium, and (2) to investigate the effect of bone strontium content on the BMD measurement using quantitative ultrasound (QUS) technique. Measurements using the research and clinical QUS systems showed a strong dependency of the BUA (broadband ultrasound attenuation) of the medium with the BMD. Moreover, increasing strontium concentrations in bone phantoms of up to 3 mol% strontium showed no effect on the BUA or the SOS values measured with either system. Therefore, the QUS technique is independent of level of bone strontium of up to 3 mol/mol [Sr/(Sr+Ca)] %.

scholarly journals Investigating the effect of strontium in bone mineral density measurements of trabecular bone mimicking phantoms using quantitative ultrasound

2021 ◽  
Author(s):  
Bisma Rizvi
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Broadband Ultrasound Attenuation ◽  
Mineral Density ◽  
Strontium Content ◽  
Gold Standard Method ◽  
Diagnosis Of Osteoporosis ◽  
X Ray ◽  
Ultrasound Attenuation

Dual-energy x-ray absorptiometry (DXA) is the current gold standard method used for the diagnosis of osteoporosis. However, it is well-established that the presence of strontium in bone could lead to significant error in measurement of bone mineral density (BMD) and diagnosis of osteoporosis using DXA. The objectives of this study are: (1) to develop novel bone-mimicking phantoms containing different concentrations of strontium, and (2) to investigate the effect of bone strontium content on the BMD measurement using quantitative ultrasound (QUS) technique. Measurements using the research and clinical QUS systems showed a strong dependency of the BUA (broadband ultrasound attenuation) of the medium with the BMD. Moreover, increasing strontium concentrations in bone phantoms of up to 3 mol% strontium showed no effect on the BUA or the SOS values measured with either system. Therefore, the QUS technique is independent of level of bone strontium of up to 3 mol/mol [Sr/(Sr+Ca)] %.

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