Diffusion Capacity and Oxygen Desaturation Effects on Exercise in Patients with Cystic Fibrosis

CHEST Journal ◽  
1987 ◽  
Vol 91 (5) ◽  
pp. 693-697 ◽  
Author(s):  
Patrick Lebecque ◽  
Jean-Guy Lapierre ◽  
André Lamarre ◽  
Allan L. Coates
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Desaturation ◽  
Diffusion Capacity

scholarly journals The impact of nocturnal oxygen desaturation on quality of life in cystic fibrosis

2011 ◽  
Vol 10 (2) ◽  
pp. 100-106 ◽  
Author(s):  
Alan C. Young ◽  
John W. Wilson ◽  
Tom C. Kotsimbos ◽  
Matthew T. Naughton
Keyword(s):  
Quality Of Life ◽  
Cystic Fibrosis ◽  
Oxygen Desaturation ◽  
The Impact

Respiratory

2020 ◽  
pp. 105-137
Author(s):  
Charlotte Frise ◽  
Sally Collins
Keyword(s):  
Cystic Fibrosis ◽  
Respiratory Failure ◽  
Lung Function ◽  
Management Strategies ◽  
Evidence Based ◽  
Lung Function Tests ◽  
Lung Volumes ◽  
Diffusion Capacity ◽  
And Diffusion ◽  
In Pregnancy

This chapter describes the respiratory changes that take place in pregnancy, infections, and pre-existing conditions that may be exacerbated or changed prior to birth. Lung function tests, including spirometry, static lung volumes, and diffusion capacity, are all described. Diseases such as tuberculosis, bronchiectasis, cystic fibrosis, and so on are described, with evidence-based management strategies. Respiratory failure and lung transplantation as well as difficulties associated with pre-existing conditions in pregnancy are also covered.

scholarly journals Influence of the Vibralung Acoustical Percussor on pulmonary function and sputum expectoration in individuals with cystic fibrosis

2018 ◽  
Vol 12 ◽  
pp. 175346661877099 ◽  
Author(s):  
Courtney M. Wheatley ◽  
Sarah E. Baker ◽  
Cori M. Daines ◽  
Hanna Phan ◽  
Marina G. Martinez ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pulmonary Function ◽  
Post Treatment ◽  
Sound Waves ◽  
Peripheral Oxygen Saturation ◽  
Diffusion Capacity ◽  
Unit Function ◽  
Therapy Sessions ◽  
Airway Clearance Therapy ◽  
Alveolar Capillary

Background: The Vibralung Acoustical Percussor is a new airway clearance therapy (ACT) utilizing intrapulmonary sound waves in addition to positive expiratory pressure (PEP). We evaluated the safety of the Vibralung and collected preliminary data on its ability to mediate sputum expectoration in individuals with cystic fibrosis (CF). Methods: Over two separate studies, 10 and 11 mild to moderate CF patients were recruited for study I and II, respectively. Study I: Vibralung was used for 20 min with either no sound (NS: PEP only) or sound (S: PEP and sound) on randomized visits. Pulmonary function, diffusion capacity of the lungs for carbon monoxide and nitric oxide (DLCO/DLNO), symptoms, and peripheral oxygen saturation (SpO2) were measured at baseline and at 1 and 4 h post treatment. Expectorated sputum was collected over 4 h post treatment. Study II: over 5 days of in-hospital therapy, the Vibralung or vibratory vest therapy (Vest) were used for two therapy sessions per day, with sputum collected for 20 min following each therapy and pulmonary function accessed pre and post each 5-day period (days 1–5 or 7–11) in a randomized crossover design. Results: Vibralung usage resulted in no change from baseline to 4 h post in pulmonary function, SpO2 or symptoms ( p > 0.05). At 4 h post therapy, the DLCO- and DLNO-derived measure of alveolar–capillary unit function (DM/ VC) showed improvement (DM/ VC = 12.5 ± 5.5 versus 7.3 ± 18.8% change, S versus NS) with no difference between S and NS ( p = 0.74). Sputum expectoration was similar between S and NS conditions (wet sputum = 10.5 ± 4.6 versus 9.9 ± 3.2 g, S versus NS, p = 0.25). There were no differences in the improvement in pulmonary function between Vibralung and Vest during either 5-day period during the hospital stay. Conclusions: Vibralung was well tolerated and caused no detrimental changes in pulmonary function metrics. The Vibralung appears to be a safe ACT in individuals with CF.

Comparison of Oxygen Desaturation during Sleep and Exercise in Patients with Cystic Fibrosis

CHEST Journal ◽  
1991 ◽  
Vol 100 (3) ◽  
pp. 659-662 ◽  
Author(s):  
Michael J. Coffey ◽  
Muiris X. FitzGerald ◽  
Walter T. McNicholas
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Desaturation

Predictability of Oxygen Desaturation During Sleep in Patients With Cystic Fibrosis

CHEST Journal ◽  
2001 ◽  
Vol 119 (2) ◽  
pp. 434-441 ◽  
Author(s):  
Despina D. Frangolias ◽  
Pearce G. Wilcox
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Desaturation

scholarly journals Oxygen desaturation during the 6-min walk test as a risk for osteoporosis in non-cystic fibrosis bronchiectasis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hung-Yu Huang ◽  
Te-Fang Sheng ◽  
Chang-Wei Lin ◽  
Ting-Wen Wang ◽  
Chun-Yu Lo ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Desaturation ◽  
Walk Test

Preserved diffusion capacity in children with cystic fibrosis

2003 ◽  
Vol 37 (1) ◽  
pp. 56-60 ◽  
Author(s):  
Peter J.F.M. Merkus ◽  
Elke S.J. Govaere ◽  
Wim H. Hop ◽  
Henk Stam ◽  
Harm A.W.M. Tiddens ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Diffusion Capacity

Carbon Monoxide Diffusion Capacity As A Predictor Of Nocturnal Oxygen Desaturation

2010 ◽  
Author(s):  
Mazen O. Al-Qadi ◽  
Ali Al-Alwan ◽  
Eric Gartman ◽  
Brian Casserly ◽  
F Dennis McCool
Keyword(s):  
Carbon Monoxide ◽  
Oxygen Desaturation ◽  
Diffusion Capacity
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