Effect of Continuous Positive Airway Pressure on Regional Cerebral Blood Flow During Wakefulness in Obstructive Sleep Apnea

CHEST Journal ◽  
2011 ◽  
Vol 140 (4) ◽  
pp. 1069A
Author(s):  
Satomi Shiota ◽  
Chie Usui ◽  
Hidenori Takekawa ◽  
Yasuko Yoshioka ◽  
Tastuo Koga ◽  
...  
Keyword(s):  
Blood Flow ◽  
Obstructive Sleep Apnea ◽  
Cerebral Blood Flow ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Regional Cerebral Blood Flow ◽  
Positive Airway Pressure ◽  
Regional Cerebral Blood ◽  
Obstructive Sleep

scholarly journals Regional Cerebral Blood Flow during Wakeful Rest in Older Subjects with Mild to Severe Obstructive Sleep Apnea

SLEEP ◽  
2015 ◽  
Vol 38 (9) ◽  
pp. 1439-1449 ◽  
Author(s):  
Andrée-Ann Baril ◽  
Katia Gagnon ◽  
Caroline Arbour ◽  
Jean-Paul Soucy ◽  
Jacques Montplaisir ◽  
...  
Keyword(s):  
Blood Flow ◽  
Obstructive Sleep Apnea ◽  
Cerebral Blood Flow ◽  
Sleep Apnea ◽  
Regional Cerebral Blood Flow ◽  
Severe Obstructive Sleep Apnea ◽  
Regional Cerebral Blood ◽  
Obstructive Sleep ◽  
Older Subjects

Altered regional cerebral blood flow in obstructive sleep apnea is associated with sleep fragmentation and oxygen desaturation

2021 ◽  
pp. 0271678X2110121
Author(s):  
Lirong Yan ◽  
Hea Ree Park ◽  
Eric J. Kezirian ◽  
Soonhyun Yook ◽  
Jae-Hun Kim ◽  
...  
Keyword(s):  
Blood Flow ◽  
Obstructive Sleep Apnea ◽  
Cerebral Blood Flow ◽  
Sleep Apnea ◽  
Default Mode Network ◽  
Cerebral Perfusion ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Attention Network ◽  
Obstructive Sleep

Altered cerebral perfusion has been reported in obstructive sleep apnea (OSA). Using dynamic susceptibility contrast MRI, we compared cerebral perfusion between male OSA patients and male healthy reference subjects and assessed correlations of perfusion abnormalities of OSA patients with sleep parameters and neuropsychological deficits at 3 T MRI, polysomnography and neuropsychological tests in 68 patients with OSA and 21 reference subjects. We found lower global and regional cerebral blood flow and cerebral blood volume, localized mainly in bilateral parietal and prefrontal cortices, as well as multiple focal cortical and deep structures related to the default mode network and attention network. In the correlation analysis between regional hypoperfusion and parameters of polysomnography, different patterns of regional hypoperfusion were distinctively associated with parameters of intermittent hypoxia and sleep fragmentation, which involved mainly parietal and orbitofrontal cortices, respectively. There was no association between brain perfusion and cognition in OSA patients in areas where significant association was observed in reference subjects, largely overlapping with nodes of the default mode network and attention network. Our results suggest that impaired cerebral perfusion in important areas of functional networks could be an important pathomechanism of neurocognitive deficits in OSA.

scholarly journals Regional cerebral blood flow alterations in obstructive sleep apnea

2013 ◽  
Vol 555 ◽  
pp. 159-164 ◽  
Author(s):  
Santosh K. Yadav ◽  
Rajesh Kumar ◽  
Paul M. Macey ◽  
Heidi L. Richardson ◽  
Danny J.J. Wang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Obstructive Sleep Apnea ◽  
Cerebral Blood Flow ◽  
Sleep Apnea ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Obstructive Sleep
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