Efficacy and Safety of Percutaneous Dilatation Tracheostomy (PDT) in Critically Ill Patients When Performed Bedside by an Intensivist With Flexible Bronchoscopy Assistance

CHEST Journal ◽  
2011 ◽  
Vol 140 (4) ◽  
pp. 193A
Author(s):  
Kyriaki Tsikritsaki ◽  
Georgios Koukoulitsios ◽  
Agisilaos Dervas ◽  
Maria Kryfti ◽  
Ioannis Dimitroulis
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Flexible Bronchoscopy ◽  
Efficacy And Safety ◽  
Percutaneous Dilatation

scholarly journals The Diagnostic Yield, Safety, and Impact of Flexible Bronchoscopy in Non-HIV Immunocompromised Critically Ill Patients in the Intensive Care Unit

Lung ◽  
2018 ◽  
Vol 196 (6) ◽  
pp. 729-736 ◽  
Author(s):  
Mazen O. Al-Qadi ◽  
Rodrigo Cartin-Ceba ◽  
Rahul Kashyap ◽  
Sumanjit Kaur ◽  
Steve G. Peters
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Diagnostic Yield ◽  
Flexible Bronchoscopy

scholarly journals Fluid Removal With Ultrasound Guided Protocol Improves the Efficacy and Safety of Dehydration in Post-Resuscitated Critically Ill Patients

Shock ◽  
2018 ◽  
Vol 50 (4) ◽  
pp. 401-407 ◽  
Author(s):  
Luhao Wang ◽  
Chunfang Qiu ◽  
Xiangdong Guan ◽  
Minying Chen ◽  
Juan Chen ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Efficacy And Safety ◽  
Ultrasound Guided ◽  
Fluid Removal

scholarly journals Parenteral polymyxins: Assessing efficacy and safety in critically ill patients with renal dysfunction

2013 ◽  
Vol 45 (6) ◽  
pp. 608 ◽  
Author(s):  
Kavita Sekhri ◽  
Ruchika Nandha ◽  
Amit Mandal ◽  
Deepak Bhasin ◽  
Harpal Singh
Keyword(s):  
Renal Dysfunction ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Efficacy And Safety

scholarly journals Efficacy and safety of once daily dosing of colistin to critically ill patients

Critical Care ◽  
2010 ◽  
Vol 14 (Suppl 1) ◽  
pp. P56
Author(s):  
A Skiada ◽  
J Pavleas ◽  
T Topalis ◽  
K Georgiou ◽  
D Siggouna ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Efficacy And Safety ◽  
Once Daily

scholarly journals A Randomized, Single-blind, Group sequential, Active-controlled Study to evaluate the clinical efficacy and safety of α-Lipoic acid for critically ill patients with coronavirus disease 2019(COVID-19)

2020 ◽  
Author(s):  
Ming Zhong ◽  
Aijun Sun ◽  
Ting Xiao ◽  
Ge Yao ◽  
Ling Sang ◽  
...  
Keyword(s):  
Placebo Group ◽  
Critically Ill ◽  
Lipoic Acid ◽  
Sofa Score ◽  
Critically Ill Patients ◽  
Standard Care ◽  
Efficacy And Safety ◽  
Group Sequential ◽  
All Cause Mortality ◽  
Single Blind

AbstractObjectTo evaluate the clinical efficacy and safety of α-Lipoic acid (ALA) for critically ill patients with coronavirus disease 2019 (COVID-19).MethodsA randomized, single-blind, group sequential, active-controlled trial was performed at JinYinTan Hospital, Wuhan, China. Between February 2020 and March 2020, 17 patients with critically ill COVID-19 were enrolled in our study. Eligible patients were randomly assigned in a 1:1 ratio to receive either ALA (1200 mg/d, intravenous infusion) once daily plus standard care or standard care plus equal volume saline infusion (placebo) for 7 days. All patients were monitored within the 7 days therapy and followed up to day 30 after therapy. The primary outcome of this study was the Sequential Organ Failure Estimate (SOFA) score, and the secondary outcome was the all-cause mortality within 30 days.ResultNine patients were randomized to placebo group and 8 patients were randomized to ALA group. SOFA score was similar at baseline, increased from 4.3 to 6.0 in the placebo group and increased from 3.8 to 4.0 in the ALA group (P=0.36) after 7 days. The 30-day all-cause mortality tended to be lower in the ALA group (3/8, 37.5%) compared to that in the placebo group (7/9, 77.8%, P=0.09).ConclusionIn our study, ALA use is associated with lower SOFA score increase and lower 30-day all-cause mortality as compared with the placebo group. Although the mortality rate was two-folds higher in placebo group than in ALA group, only borderline statistical difference was evidenced due to the limited patient number. Future studies with larger patient cohort are warranted to validate the role of ALA in critically ill patients with COVID-19.

Effects of glutamine supplementation on critically ill patients: Focus on efficacy and safety. An overview of systematic reviews

Nutrition ◽  
2020 ◽  
Vol 78 ◽  
pp. 110960
Author(s):  
Aikaterini Apostolopoulou ◽  
Anna-Bettina Haidich ◽  
Konstantinia Kofina ◽  
William Manzanares ◽  
Emmanouil Bouras ◽  
...  
Keyword(s):  
Critically Ill ◽  
Systematic Reviews ◽  
Critically Ill Patients ◽  
Glutamine Supplementation ◽  
Efficacy And Safety ◽  
Overview Of Systematic Reviews
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