scholarly journals Real-Time High Resolution 3D Imaging of the Lyme Disease Spirochete Adhering to and Escaping from the Vasculature of a Living Host

2008 ◽  
Vol 4 (6) ◽  
pp. e1000090 ◽  
Author(s):  
Tara J. Moriarty ◽  
M. Ursula Norman ◽  
Pina Colarusso ◽  
Troy Bankhead ◽  
Paul Kubes ◽  
...  
Keyword(s):  
High Resolution ◽  
Lyme Disease ◽  
Real Time ◽  
3D Imaging

Development of long range, real-time, and high resolution 3D imaging ladar

2011 ◽  
Author(s):  
Shumpei Kameyama ◽  
Masaharu Imaki ◽  
Akihito Hirai ◽  
Hidenobu Tsuji ◽  
Nobuki Kotake ◽  
...  
Keyword(s):  
High Resolution ◽  
Real Time ◽  
Long Range ◽  
3D Imaging

scholarly journals Noninvasive intravital high-resolution imaging of pancreatic neuroendocrine tumours

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mirela Balan ◽  
Marta Trusohamn ◽  
Frank Chenfei Ning ◽  
Stefan Jacob ◽  
Kristian Pietras ◽  
...  
Keyword(s):  
High Resolution ◽  
Real Time ◽  
3D Imaging ◽  
Tumour Growth ◽  
Neuroendocrine Tumours ◽  
Laser Scanning Microscopy ◽  
High Resolution Imaging ◽  
Tumour Angiogenesis ◽  
Pancreatic Neuroendocrine Tumours ◽  
Resolution Imaging

Abstract Preclinical trials of cancer drugs in animal models are important for drug development. The Rip1Tag2 (RT2) transgenic mouse, a model of pancreatic neuroendocrine tumours (PNET), has provided immense knowledge about PNET biology, although tumour progression occurs in a location inaccessible for real-time monitoring. To overcome this hurdle we have developed a novel platform for intravital 3D imaging of RT2 tumours to facilitate real-time studies of cancer progression. Pre-oncogenic islets retrieved from RT2 mice were implanted into the anterior chamber of the eye (ACE) of host mice, where they engrafted on the iris, recruited blood vessels and showed continuous growth. Noninvasive confocal and two-photon laser-scanning microscopy through the transparent cornea facilitated high-resolution imaging of tumour growth and angiogenesis. RT2 tumours in the ACE expanded up to 8-fold in size and shared hallmarks with tumours developing in situ in the pancreas. Genetically encoded fluorescent reporters enabled high-resolution imaging of stromal cells and tumour cell migration. Sunitinib treatment impaired RT2 tumour angiogenesis and growth, while overexpression of the vascular endothelial growth factor (VEGF)-B increased tumour angiogenesis though tumour growth was impaired. In conclusion, we present a novel platform for intravital high-resolution and 3D imaging of PNET biology and cancer drug assessment.

scholarly journals High resolution, wide field of view, real time 340GHz 3D imaging radar for security screening

2017 ◽  
Author(s):  
Duncan A. Robertson ◽  
David G. Macfarlane ◽  
Robert I. Hunter ◽  
Scott L. Cassidy ◽  
Nuria Llombart ◽  
...  
Keyword(s):  
High Resolution ◽  
Real Time ◽  
3D Imaging ◽  
Field Of View ◽  
Wide Field ◽  
Security Screening ◽  
Imaging Radar ◽  
Wide Field Of View

High-resolution, real-time 3D imaging with fringe analysis

2010 ◽  
Vol 7 (1) ◽  
pp. 55-66 ◽  
Author(s):  
Nikolaus Karpinsky ◽  
Song Zhang
Keyword(s):  
High Resolution ◽  
Real Time ◽  
3D Imaging ◽  
Fringe Analysis

High-resolution real-time 3D imaging using time-gated photorefractive holography

1998 ◽  
Author(s):  
Mary Tziraki ◽  
Richard Jones ◽  
Duncan Parsons-Karavassilis ◽  
Paul M. W. French ◽  
K. M. Kwolek ◽  
...  
Keyword(s):  
High Resolution ◽  
Real Time ◽  
3D Imaging
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