scholarly journals Rac1 Is Required for Epithelial Stem Cell Function during Dermal and Oral Mucosal Wound Healing but Not for Tissue Homeostasis in Mice

PLoS ONE ◽  
2010 ◽  
Vol 5 (5) ◽  
pp. e10503 ◽  
Author(s):  
Rogerio M. Castilho ◽  
Cristiane H. Squarize ◽  
Kantima Leelahavanichkul ◽  
Yi Zheng ◽  
Thomas Bugge ◽  
...  
2013 ◽  
Vol 12 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Paola Koenen ◽  
Timo A Spanholtz ◽  
Marc Maegele ◽  
Ewa Stürmer ◽  
Thomas Brockamp ◽  
...  

2019 ◽  
Vol 20 (4) ◽  
pp. 891 ◽  
Author(s):  
Francisco Santos ◽  
Cristiana Moreira ◽  
Sandrina Nóbrega-Pereira ◽  
Bruno Bernardes de Jesus

Epithelial–mesenchymal transition (EMT) is a cellular process by which differentiated epithelial cells undergo a phenotypic conversion to a mesenchymal nature. The EMT has been increasingly recognized as an essential process for tissue fibrogenesis during disease and normal aging. Higher levels of EMT proteins in aged tissues support the involvement of EMT as a possible cause and/or consequence of the aging process. Here, we will highlight the existing understanding of EMT supporting the phenotypical alterations that occur during normal aging or pathogenesis, covering the impact of EMT deregulation in tissue homeostasis and stem cell function.


2009 ◽  
Vol 9 (1) ◽  
pp. 4 ◽  
Author(s):  
Richard L Mort ◽  
Thaya Ramaesh ◽  
Dirk A Kleinjan ◽  
Steven D Morley ◽  
John D West

2021 ◽  
Author(s):  
Anna Altshuler ◽  
Aya Amitai-Lange ◽  
Noam Tarazi ◽  
Sunanda Dey ◽  
Lior Strinkovsky ◽  
...  

2005 ◽  
Vol 8 (5) ◽  
pp. 635-649 ◽  
Author(s):  
Peter W. Reddien ◽  
Adam L. Bermange ◽  
Kenneth J. Murfitt ◽  
Joya R. Jennings ◽  
Alejandro Sánchez Alvarado

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