scholarly journals Entomopathogenic fungal infection leads to temporospatial modulation of the mosquito immune system

2018 ◽  
Vol 12 (4) ◽  
pp. e0006433 ◽  
Author(s):  
José L. Ramirez ◽  
Christopher A. Dunlap ◽  
Ephantus J. Muturi ◽  
Ana B. F. Barletta ◽  
Alejandro P. Rooney
2020 ◽  
Vol 76 (12) ◽  
pp. 3982-3989
Author(s):  
Jianyang Bai ◽  
Zhe Xu ◽  
Lu Li ◽  
Wei Ma ◽  
Letian Xu ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Antonio Dionízio De Albuquerque Neto ◽  
André Vitor Alves Araújo ◽  
Daniel Assunção Cerqueira ◽  
Lorenzzo De Angeli Cesconetto ◽  
Nilton Provenzano ◽  
...  

Paracoccidioidomycosis is a fungal infection initially described in Brazil in 1908 by Adolfo Lutz. Manifestation of this disease depends on numerous factors, such as microorganism virulence, hormonal profile, genetic predisposition, nutrition, and immune system. It is characterized classically by cutaneous lesions, lymphadenopathy, and pulmonary involvement. It presents male predilection, which can be explained by the protective effect of female hormones. Classic presentation within oral cavity is a superficial ulcer characterized by hemorrhagic dots of moriform aspect. Treatment should be established individually and closely monitored. This manuscript aims at reporting five cases of this pathology.


2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Yosuke Seto ◽  
Koichiro Tamura

The innate immune system ofDrosophilais activated by ingestion of microorganisms.D. melanogasterbreeds on fruits fermented bySaccharomyces cerevisiae, whereasD. virilisbreeds on slime flux and decaying bark of tree housing a variety of bacteria, yeasts, and molds. In this study, it is shown thatD. virilishas a higher resistance to oral infection of a species of filamentous fungi belonging to the genusPenicilliumcompared toD. melanogaster. In response to the fungal infection, a transcriptome profile of immune-related genes was considerably different betweenD. melanogasterandD. virilis: the genes encoding antifungal peptides, Drosomycin and Metchnikowin, were highly expressed inD. melanogasterwhereas, the genes encoding Diptericin and Defensin were highly expressed inD. virilis. On the other hand, the immune-induced molecule (IM) genes showed contrary expression patterns between the two species: they were induced by the fungal infection inD. melanogasterbut tended to be suppressed inD. virilis. Our transcriptome analysis also showed newly predicted immune-related genes inD. virilis. These results suggest that the innate immune system has been extensively differentiated during the evolution of theseDrosophilaspecies.


2006 ◽  
Vol 193 (10) ◽  
pp. 1427-1436 ◽  
Author(s):  
Ekaterina Dadachova ◽  
Ruth A. Bryan ◽  
Christos Apostolidis ◽  
Alfred Morgenstern ◽  
Tong Zhang ◽  
...  

2021 ◽  
Vol 14 ◽  
pp. 117863612110530
Author(s):  
Meet Kamal Dwivedi ◽  
Ashutosh Dwivedi

Risk groups for mucormycosis include persons with immunosuppressed immune system and uncontrolled diabetes. The patients suffering from corona virus or post covid patients have been found to be entrapped with this fungal infection due to suppression in the immune system. Also the major attack was reported in those patients who were in Intensive Care units. It arises due to the fungal infection of various species and can occur simultaneously with covid. The development of black fungus mostly affects lungs, eyes, brain, and skin and is not at all contagious. Proper diagnostic can only predict that the patient is in invasive attack of which mucor species. It is better to take prevention by wearing medicated masks, hand gloves, wearing glasses, avoid dusty and damp places.


2021 ◽  
Vol 14 (11) ◽  
pp. e243694
Author(s):  
Kristen Zeitler ◽  
Ripal Jariwala ◽  
Sally Alrabaa ◽  
Chakrapol Sriaroon

Ruxolitinib (RUX) is a kinase inhibitor used in the treatment of various medical conditions and its mechanism of action involves suppression of the immune system. While beneficial in treatment of polycythemia vera, myelofibrosis and other indications, it can also increase a patient’s susceptibility to various infections, including bacterial, viral and fungal. We present a case of a patient being treated with RUX who presented with a disseminated fungal infection. This case emphasises the need for vigilance of endemic fungal infections in individuals who are on RUX therapy.


2021 ◽  
pp. 63-64
Author(s):  
Chetna Sen ◽  
Pushkar Gupta ◽  
Sneha S Mantri

Mucormycosis is a fungal infection which has drawn everyone's attention after an enormous outbreak in covid-19 patients who have been hospitalized. Even those covid-19 positive patients who were at home, but were treated with steroid therapy without any oxygen support had developed this serious infection. Steroid therapy compromised their immune system thereby facilitating exponential growth of this commonly found fungus in the environment, which was previously harmless. Incidences of this disease has become so frequent that it has been declared an epidemic in various states of India by the local government. It has already created a widespread havoc in our Healthcare system along with fatally compromising the health of some patients and handicapping others due to the surgery required to remove infected eye or necrosed alveolar bone. This requires rehabilitation of lost part to regain function and esthetics.


2021 ◽  
pp. 6-7
Author(s):  
Debarshi Mahato

Fungus-caused illnesses are widespread in plants, but owing to the protective barrier given by the immune system of living creatures, fungal infection is uncommon in humans and animals. Notwithstanding, for the most part in current circumstance, when the destructive Coronavirus contamination has undermined the insusceptible capacity, the apparently innocuous parasitic gathering makes a move to assault the human body, which might be serious. The contagious microbe penetrates the human body by means of wounds or through the respiratory framework. The human body is inltrated by the fungal infection through injuries or the respiratory system. Therefore, when it penetrates bodily tissue, it sucks it up for nourishment and resists the immunological impediment. The globe is presently actively ghting the new Covid; Out of nowhere, another rush of tiny invaders known as black, white, and yellow contagious diseases has inicted damage on the all-around tough epidemic.


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