scholarly journals Raman enhancement properties of Ag nano-islands with SiO₂ microsphere array prepared by self-assembly technology and thin-film annealing method

2021 ◽  
Author(s):  
Junfan Chen ◽  
Hongxian Chen ◽  
Jie Zhang ◽  
Yong Zhu
Keyword(s):  
Thin Film ◽  
Self Assembly ◽  
Raman Enhancement ◽  
Assembly Technology ◽  
Film Annealing ◽  
Annealing Method ◽  
Microsphere Array

scholarly journals Construction of Chitosan/Alginate Nano-Drug Delivery System for Improving Dextran Sodium Sulfate-Induced Colitis in Mice

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1884
Author(s):  
Mengfei Jin ◽  
Shangyong Li ◽  
Yanhong Wu ◽  
Dandan Li ◽  
Yantao Han
Keyword(s):  
Self Assembly ◽  
Average Diameter ◽  
Mucosal Healing ◽  
Plga Nanoparticles ◽  
Narrow Particle Size Distribution ◽  
Layer By Layer ◽  
Systemic Side Effects ◽  
Assembly Technology ◽  
The Fourier Transform ◽  
Polyelectrolyte Film

(1) Background: In the treatment of ulcerative colitis (UC), accurate delivery and release of anti-inflammatory drugs to the site of inflammation can reduce systemic side effects. (2) Methods: We took advantage of this goal to prepare resveratrol-loaded PLGA nanoparticles (RES-PCAC-NPs) by emulsification solvent volatilization. After layer-by-layer self-assembly technology, we deposited chitosan and alginate to form a three-layer polyelectrolyte film. (3) Results: It can transport nanoparticles through the gastric environment to target inflammation sites and slowly release drugs at a specific pH. The resulting RES-PCAC-NPs have an ideal average diameter (~255 nm), a narrow particle size distribution and a positively charged surface charge (~13.5 mV). The Fourier transform infrared spectroscopy showed that resveratrol was successfully encapsulated into PCAC nanoparticles, and the encapsulation efficiency reached 87.26%. In addition, fluorescence imaging showed that RES-PCAC-NPs with positive charges on the surface can effectively target and accumulate in the inflammation site while continuing to penetrate downward to promote mucosal healing. Importantly, oral RES-PCAC-NPs treatment in DSS-induced mice was superior to other results in significantly improved inflammatory markers of UC. (4) Conclusions: Our results strongly prove that RES-PCAC-NPs can target the inflamed colon for maximum efficacy, and this oral pharmaceutical formulation can represent a promising formulation in the treatment of UC.

A simulation study of self-assembly of ABC star terpolymers confined between two parallel surfaces

Soft Matter ◽  
2021 ◽  
Author(s):  
Zhiyao Liu ◽  
Zheng Wang ◽  
Yuhua Yin ◽  
Run Jiang ◽  
Baohui Li
Keyword(s):  
Simulated Annealing ◽  
Phase Behavior ◽  
Phase Diagrams ◽  
Simulation Study ◽  
Self Assembly ◽  
Simulated Annealing Method ◽  
Parallel Surfaces ◽  
Annealing Method

Phase behavior of ABC star terpolymers confined between two identical parallel surfaces is systematically studied with a simulated annealing method. Several phase diagrams are constructed for systems with different bulk...

scholarly journals Precise Synthesis and Thin Film Self-Assembly of PLLA-b-PS Bottlebrush Block Copolymers

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1412
Author(s):  
Eunkyung Ji ◽  
Cian Cummins ◽  
Guillaume Fleury
Keyword(s):  
Thin Film ◽  
Block Copolymers ◽  
Self Assembly ◽  
Ring Opening ◽  
Periodic Structures ◽  
One Pot ◽  
Ordered Structures ◽  
Carbonyl Chloride ◽  
Thin Film Patterning ◽  
Nanoporous Templates

The ability of bottlebrush block copolymers (BBCPs) to self-assemble into ordered large periodic structures could greatly expand the scope of photonic and membrane technologies. In this paper, we describe a two-step synthesis of poly(l-lactide)-b-polystyrene (PLLA-b-PS) BBCPs and their rapid thin-film self-assembly. PLLA chains were grown from exo-5-norbornene-2-methanol via ring-opening polymerization (ROP) of l-lactide to produce norbornene-terminated PLLA. Norbonene-terminated PS was prepared using anionic polymerization followed by a termination reaction with exo-5-norbornene-2-carbonyl chloride. PLLA-b-PS BBCPs were prepared from these two norbornenyl macromonomers by a one-pot sequential ring opening metathesis polymerization (ROMP). PLLA-b-PS BBCPs thin-films exhibited cylindrical and lamellar morphologies depending on the relative block volume fractions, with domain sizes of 46–58 nm and periodicities of 70–102 nm. Additionally, nanoporous templates were produced by the selective etching of PLLA blocks from ordered structures. The findings described in this work provide further insight into the controlled synthesis of BBCPs leading to various possible morphologies for applications requiring large periodicities. Moreover, the rapid thin film patterning strategy demonstrated (>5 min) highlights the advantages of using PLLA-b-PS BBCP materials beyond their linear BCP analogues in terms of both dimensions achievable and reduced processing time.

Electrochemical Characteristics of Aptasensor Based on MEMS Thin-Film Gold Electrode

2013 ◽  
Vol 562-565 ◽  
pp. 441-445
Author(s):  
Yan Xia Yan ◽  
Li Ying Jiang ◽  
Fen Fen Wang ◽  
Yan Zhang ◽  
Jie Hu
Keyword(s):  
Thin Film ◽  
Self Assembly ◽  
Gold Electrode ◽  
Ac Impedance ◽  
Optimum Concentration ◽  
Electrochemical Characteristics ◽  
Universal Method

A new fabrication methods of thin-film gold electrode is reported. Electrochemical characteristics of self-assembly aptasensor based on MEMS thin-film gold electrode has been studied by lots of experiments, characteristics include immobilizing time, AC impedance, CV curves. Experiments indicate immobilizing time of DNA-SH on gold electrode is more than 15 hours. CV curves and AC impedance of MEMS thin-film gold electrode show the same conclusion that 20μm/L DNA is optimum concentration when DNA is immobilized on gold electrode. Those results present a potential universal method for other aptasensors.

Precrystalline P3HT nanowires: growth-controllable solution processing and effective molecular packing transfer to thin-film

CrystEngComm ◽  
2022 ◽  
Author(s):  
Seon-Mi Jin ◽  
Jun Ho Hwang ◽  
Jung Ah Lim ◽  
Eunji Lee
Keyword(s):  
Thin Film ◽  
Conjugated Polymers ◽  
Self Assembly ◽  
Optoelectronic Devices ◽  
Molecular Packing ◽  
Solution Processing ◽  
Roll To Roll ◽  
Nanowires Growth ◽  
Fundamental Research ◽  
Significant Attention

Solution-processable precrystalline nanowires (NWs) of conjugated polymers (CPs) have garnered significant attention in fundamental research based on crystallization-driven self-assembly and in the roll-to-roll fabrication of optoelectronic devices such as organic...

Symmetric Poly(ethylene oxide-b-styrene-b-isoprene) Triblock Copolymers: Synthesis, Characterization, and Self-Assembly in Bulk and Thin Film

2014 ◽  
Vol 47 (18) ◽  
pp. 6373-6381 ◽  
Author(s):  
Yali Qiao ◽  
Rachel Ferebee ◽  
Bongjoon Lee ◽  
Indranil Mitra ◽  
Nathaniel A. Lynd ◽  
...  
Keyword(s):  
Thin Film ◽  
Ethylene Oxide ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene
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