scholarly journals Cross-sectional refractive-index variations in fiber Bragg gratings measured by quantitative phase imaging

2019 ◽  
Vol 45 (1) ◽  
pp. 53 ◽  
Author(s):  
Grayson M. Noah ◽  
Yijun Bao ◽  
Thomas K. Gaylord
2018 ◽  
Vol 26 (8) ◽  
pp. 10729 ◽  
Author(s):  
Paul Müller ◽  
Mirjam Schürmann ◽  
Salvatore Girardo ◽  
Gheorghe Cojoc ◽  
Jochen Guck

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Manoj Kumar ◽  
Xiangyu Quan ◽  
Yasuhiro Awatsuji ◽  
Yosuke Tamada ◽  
Osamu Matoba

2017 ◽  
Author(s):  
Masanori Takabayashi ◽  
Hassaan Majeed ◽  
Andre Kajdacsy-Balla ◽  
Gabriel Popescu

AbstractTissue refractive index provides important information about morphology at the nanoscale. Since the malignant transformation involves both intra- and inter-cellular changes in the refractive index map, the tissue disorder measurement can be used to extract important diagnosis information. Quantitative phase imaging (QPI) provides a practical means of extracting this information as it maps the optical path-length difference (OPD) across a tissue sample with sub-wavelength sensitivity. In this work, we employ QPI to compare the tissue disorder strength between benign and malignant breast tissue histology samples. Our results show that disease progression is marked by a significant increase in the disorder strength. Since our imaging system can be added as an upgrading module to an existing microscope, we anticipate that it can be integrated easily in the pathology work flow.


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