scholarly journals Influence of the refractive index-mismatch at the boundaries measured in fluorescenceenhanced frequency-domain photon migration imaging

2002 ◽  
Vol 10 (15) ◽  
pp. 653 ◽  
Author(s):  
Anuradha Godavarty ◽  
Daniel Hawrysz ◽  
Ranadhir Roy ◽  
Eva Sevick-Muraca ◽  
Margaret Eppstein
Keyword(s):  
Refractive Index ◽  
Frequency Domain ◽  
Photon Migration ◽  
Migration Imaging

Multipixel Techniques for Frequency-Domain Photon Migration Imaging

1997 ◽  
Vol 13 (5) ◽  
pp. 669-680 ◽  
Author(s):  
J.S. Reynolds ◽  
T.L. Troy ◽  
E.M. Sevick-Muraca
Keyword(s):  
Frequency Domain ◽  
Photon Migration ◽  
Migration Imaging

MCVM: MONTE CARLO MODELING OF PHOTON MIGRATION IN VOXELIZED MEDIA

2010 ◽  
Vol 03 (02) ◽  
pp. 91-102 ◽  
Author(s):  
TING LI ◽  
HUI GONG ◽  
QINGMING LUO
Keyword(s):  
Monte Carlo ◽  
Refractive Index ◽  
High Precision ◽  
Heterogeneous Media ◽  
Homogeneous Medium ◽  
Software Tool ◽  
Light Transport ◽  
Photon Migration ◽  
Monte Carlo Code ◽  
Monte Carlo Modeling

The Monte Carlo code MCML (Monte Carlo modeling of light transport in multi-layered tissue) has been the gold standard for simulations of light transport in multi-layer tissue, but it is ineffective in the presence of three-dimensional (3D) heterogeneity. New techniques have been attempted to resolve this problem, such as MCLS, which is derived from MCML, and tMCimg, which draws upon image datasets. Nevertheless, these approaches are insufficient because of their low precision or simplistic modeling. We report on the development of a novel model for photon migration in voxelized media (MCVM) with 3D heterogeneity. Voxel crossing detection and refractive-index-unmatched boundaries were considered to improve the precision and eliminate dependence on refractive-index-matched tissue. Using a semi-infinite homogeneous medium, steady-state and time-resolved simulations of MCVM agreed well with MCML, with high precision (~100%) for the total diffuse reflectance and total fractional absorption compared to those of tMCimg (< 70%). Based on a refractive-index-matched heterogeneous skin model, the results of MCVM were found to coincide with those of MCLS. Finally, MCVM was applied to a two-layered sphere with multi-inclusions, which is an example of a 3D heterogeneous media with refractive-index-unmatched boundaries. MCVM provided a reliable model for simulation of photon migration in voxelized 3D heterogeneous media, and it was developed to be a flexible and simple software tool that delivers high-precision results.

scholarly journals Sampling tissue volumes using frequency-domain photon migration

2004 ◽  
Vol 69 (5) ◽  
Author(s):  
Frédéric Bevilacqua ◽  
Joon S. You ◽  
Carole K. Hayakawa ◽  
Vasan Venugopalan
Keyword(s):  
Frequency Domain ◽  
Photon Migration

Spatial resonances of the Cherenkov emission in dispersive metamaterials

2013 ◽  
Vol 1617 ◽  
pp. 181-185
Author(s):  
Gennadiy Burlak ◽  
Erika Martinez-Sanchez
Keyword(s):  
Refractive Index ◽  
Spatial Structure ◽  
Frequency Domain ◽  
Frequency Spectrum ◽  
Specific Interaction ◽  
Optical Emission ◽  
Frequency Range

ABSTRACTWe systematically study the Cherenkov optical emission by a nonrelativistic modulated source crossing 3D dispersive metamaterial. It is found that the interference of the field produced by the modulated source with the periodic plasmonic-polariton excitations leads to the specific interaction in the frequency range where the dispersive refractive index of a metamaterial is negative. Such resonance considerably modifies the spatial structure of the Cherenkov fieldand the reversed Cherenkov emission. In our study parameters of metamaterial and modulated source are fixed while the frequency spectrum of the plasmonic excitations is formed due to the fields interplay in the frequency domain.

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