Surface Plasmon Resonance Nanohole Array Sensor and its Application on Protein Specific Binding

2007 ◽  
Author(s):  
Lin Pang ◽  
Grace M. Hwang ◽  
Yeshaiahu Fainman
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Specific Binding ◽  
Nanohole Array ◽  
Array Sensor

Handheld nanohole array surface plasmon resonance sensing platform

2010 ◽  
Author(s):  
J. Campbell ◽  
C. Escobedo ◽  
A. I. K. Choudhury ◽  
J. T. Blakely ◽  
A. G. Brolo ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Nanohole Array ◽  
Sensing Platform

Localized and Propagating Surface Plasmon Resonance Sensors: A Study Using Carbohydrate Binding Protein

2005 ◽  
Vol 876 ◽  
Author(s):  
Chanda Yonzon ◽  
Richard P. Van Duyne
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Specific Binding ◽  
Gold Surface ◽  
Optical Biosensor ◽  
Localized Surface Plasmon ◽  
Carbohydrate Binding ◽  
Binding Studies ◽  
Assembled Monolayers

AbstractThis work encompasses a comparative analysis of the properties of two optical biosensor platforms: (1) the propagating surface plasmon resonance (SPR) sensor based on a planar, thin film gold surface and (2) the localized surface plasmon resonance (LSPR) sensor based on surface confined Ag nanoparticles fabricated by nanosphere lithography. The binding of Concanavalin A (ConA) to mannose-functionalized self-assembled monolayers (SAMs) is chosen to illustrate the similarities and the differences of these sensors. A comprehensive set of non-specific binding studies demonstrate that the single transduction mechanism is due to the specific binding of ConA to the mannose-functionalized surface. Finally, an elementary (2x1) multiplexed version of a LSPR carbohydrate sensing chip to probe the simultaneous binding of ConA to mannose and galactose-functionalized SAMs is also demonstrated.

Electrofocusing-enhanced localized surface plasmon resonance biosensors

Nanoscale ◽  
2015 ◽  
Vol 7 (41) ◽  
pp. 17244-17248 ◽  
Author(s):  
Jinling Zhang ◽  
Yi Wang ◽  
Ten It Wong ◽  
Xiaohu Liu ◽  
Xiaodong Zhou ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Serum Albumin ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Troponin I ◽  
Localized Surface Plasmon ◽  
Plasmonic Sensor ◽  
Nanohole Array

An electrofocusing-enhanced plasmonic sensor was developed on a gold nanohole array to promote the capture of human troponin I while repelling serum albumin.

Localized surface plasmon resonance sensing structure based on gold nanohole array on beveled fiber edge

2017 ◽  
Vol 28 (43) ◽  
pp. 435504 ◽  
Author(s):  
Enming Zhao ◽  
Peipei Jia ◽  
Heike Ebendorff-Heidepriem ◽  
Hanyang Li ◽  
Peng Huang ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Localized Surface Plasmon ◽  
Nanohole Array

scholarly journals High-Affinity, Protective Antibodies to the Binding Domain of Botulinum Neurotoxin Type A

2001 ◽  
Vol 69 (1) ◽  
pp. 570-574 ◽  
Author(s):  
Dorothy D. Pless ◽  
Edna R. Torres ◽  
Emily K. Reinke ◽  
Sina Bavari
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Botulinum Neurotoxin ◽  
Epitope Mapping ◽  
Dissociation Constants ◽  
Specific Binding ◽  
Binding Domain ◽  
Protective Antibodies ◽  
Fusion Products

ABSTRACT Monoclonal antibodies (MAbs) were prepared against the putative binding domain of botulinum neurotoxin A (BoNT/A), a nontoxic 50-kDa fragment. Initially, all fusion products were screened against the holotoxin BoNT/A and against the binding fragment, BoNT/A HC. Eleven neutralizing hybridomas were cloned, and their specific binding to BoNT/A HC was demonstrated by surface plasmon resonance, with dissociation constants ranging from 0.9 to <0.06 nM. Epitope mapping by real-time surface plasmon resonance showed that the antibodies bound to at least two distinct regions of the BoNT/A HC fragment. These MAbs will be useful tools for studying BoNT/A interactions with its receptor, and they have potential diagnostic and therapeutic applications.

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