Electrofocusing-enhanced localized surface plasmon resonance biosensors

Nanoscale ◽  
2015 ◽  
Vol 7 (41) ◽  
pp. 17244-17248 ◽  
Author(s):  
Jinling Zhang ◽  
Yi Wang ◽  
Ten It Wong ◽  
Xiaohu Liu ◽  
Xiaodong Zhou ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Serum Albumin ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Troponin I ◽  
Localized Surface Plasmon ◽  
Plasmonic Sensor ◽  
Nanohole Array

An electrofocusing-enhanced plasmonic sensor was developed on a gold nanohole array to promote the capture of human troponin I while repelling serum albumin.

Localized surface plasmon resonance sensing structure based on gold nanohole array on beveled fiber edge

2017 ◽  
Vol 28 (43) ◽  
pp. 435504 ◽  
Author(s):  
Enming Zhao ◽  
Peipei Jia ◽  
Heike Ebendorff-Heidepriem ◽  
Hanyang Li ◽  
Peng Huang ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Localized Surface Plasmon ◽  
Nanohole Array

scholarly journals Fabrication of Troponin I Biosensor Composed of Multi-Functional DNA Structure/Au Nanocrystal Using Electrochemical and Localized Surface Plasmon Resonance Dual-Detection Method

Nanomaterials ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 1000 ◽  
Author(s):  
Taek Lee ◽  
Jinmyeong Kim ◽  
Inho Nam ◽  
Yeonju Lee ◽  
Ha Eun Kim ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Human Serum ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Troponin I ◽  
Electrochemical Impedance ◽  
Localized Surface Plasmon ◽  
Dual Mode ◽  
Functional Dna

In the present study, we fabricated a dual-mode cardiac troponin I (cTnI) biosensor comprised of multi-functional DNA (MF-DNA) on Au nanocrystal (AuNC) using an electrochemical method (EC) and a localized surface plasmon resonance (LSPR) method. To construct a cTnI bioprobe, a DNA 3 way-junction (3WJ) was prepared to introduce multi-functionality. Each DNA 3WJ arm was modified to possess a recognition region (Troponin I detection aptamer), an EC-LSPR signal generation region (methylene blue: MB), and an anchoring region (Thiol group), respectively. After an annealing step, the multi-functional DNA 3WJ was assembled, and its configuration was confirmed by Native-TBM PAGE for subsequent use in biosensor construction. cTnI was also expressed and purified for use in biosensor experiments. To construct an EC-LSPR dual-mode biosensor, AuNCs were prepared on an indium-tin-oxide (ITO) substrate using an electrodeposition method. The prepared multi-functional (MF)-DNA was then immobilized onto AuNCs by covalent bonding. Field emission scanning electron microscope (FE-SEM) and atomic force microscopy (AFM) were used to analyze the surface morphology. LSPR and electrochemical impedance spectroscopy (EIS) experiments were performed to confirm the binding between the target and the bioprobe. The results indicated that cTnI could be effectively detected in the buffer solution and in diluted-human serum. Based on the results of these experiments, the loss on drying (LOD) was determined to be 1.0 pM in HEPES solution and 1.0 pM in 10% diluted human serum. Additionally, the selectivity assay was successfully tested using a number of different proteins. Taken together, the results of our study indicate that the proposed dual-mode biosensor is applicable for use in field-ready cTnI diagnosis systems for emergency situations.

Strain‐Induced Modulation of Localized Surface Plasmon Resonance in Ultrathin Hexagonal Gold Nanoplates

2021 ◽  
pp. 2100653
Author(s):  
Gyeong‐Su Park ◽  
Kyung Suk Min ◽  
Hyuksang Kwon ◽  
Sangwoon Yoon ◽  
Sangwon Park ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Localized Surface Plasmon

An Eye-Shaped Ultra-Sensitive Localized Surface Plasmon Resonance–Based Biochemical Sensor

Plasmonics ◽  
2021 ◽  
Author(s):  
Mohammad Rakibul Islam ◽  
Fahim Yasir ◽  
Md. Rakib Hossain Antor ◽  
Mahmudul Hassan Turja ◽  
Ashikur Rahman ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Localized Surface Plasmon ◽  
Biochemical Sensor

scholarly journals Localized surface plasmon resonance in deep ultraviolet region below 200 nm using a nanohemisphere on mirror structure

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kohei Shimanoe ◽  
Soshi Endo ◽  
Tetsuya Matsuyama ◽  
Kenji Wada ◽  
Koichi Okamoto
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Localized Surface Plasmon ◽  
Ultraviolet Region ◽  
Simple Method ◽  
Thin Film Layer ◽  
Deep Ultraviolet ◽  
Two Peaks

AbstractLocalized surface plasmon resonance (LSPR) was performed in the deep ultraviolet (UVC) region with Al nanohemisphere structures fabricated by means of a simple method using a combination of vapor deposition, sputtering, and thermal annealing without top-down nanofabrication technology such as electron beam lithography. The LSPR in the UV region was obtained and tuned by the initial metal film thickness, annealing temperature, and dielectric spacer layer thickness. Moreover, we achieved a flexible tuning of the LSPR in a much deeper UVC region below 200 nm using a nanohemisphere on a mirror (NHoM) structure. NHoM is a structure in which a metal nanohemisphere is formed on a metal substrate that is interposed with an Al2O3 thin film layer. In the experimental validation, Al and Ga were used for the metal hemispheres. The LSPR spectrum of the NHoM structures was split into two peaks, and the peak intensities were enhanced and sharpened. The shorter branch of the LSPR peak appeared in the UVC region below 200 nm. Both the peak intensities and linewidth were flexibly tuned by the spacer thickness. This structure can contribute to new developments in the field of deep UV plasmonics.

Plasma enhanced label-free immunoassay for alpha-fetoprotein based on a U-bend fiber-optic LSPR biosensor

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 23990-23998 ◽  
Author(s):  
Gaoling Liang ◽  
Zhongjun Zhao ◽  
Yin Wei ◽  
Kunping Liu ◽  
Wenqian Hou ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Fiber Optic ◽  
Cost Effective ◽  
Alpha Fetoprotein ◽  
Localized Surface Plasmon ◽  
Label Free

A simple, label-free and cost-effective localized surface plasmon resonance (LSPR) immunosensing method was developed for detection of alpha-fetoprotein (AFP).

scholarly journals Design and validation of fiber optic localized surface plasmon resonance sensor for thyroglobulin immunoassay with high sensitivity and rapid detection

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hyeong-Min Kim ◽  
Dae Hong Jeong ◽  
Ho-Young Lee ◽  
Jae-Hyoung Park ◽  
Seung-Ki Lee
Keyword(s):  
Surface Plasmon Resonance ◽  
Optical Fiber ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Optical Fiber Sensor ◽  
Fiber Sensor ◽  
Localized Surface Plasmon ◽  
Simple Method ◽  
Resonance Sensor

AbstractA simple optical fiber sensor based on localized surface plasmon resonance was constructed for direct and rapid measurement of thyroglobulin (Tg). Specific tests for Tg in patients that have undergone thyroidectomy are limited because of insufficient sensitivity, complicated procedures, and in some cases, a long time to yield a result. A sensitive, fast, and simple method is necessary to relieve the psychological and physical burden of the patient. Various concentrations of Tg were measured in a microfluidic channel using an optical fiber sensor with gold nanoparticles. The sensor chip has a detection limit of 93.11 fg/mL with no specificity for other antigens. The potential applicability of the Tg sensing system was evaluated using arbitrary samples containing specific concentrations of Tg. Finally, the sensor can be employed to detect Tg in the patient’s serum, with a good correlation when compared with the commercial kit.

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