scholarly journals Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography

2016 ◽  
Vol 7 (9) ◽  
pp. 3377 ◽  
Author(s):  
Siyu Chen ◽  
Qi Liu ◽  
Xiao Shu ◽  
Brian Soetikno ◽  
Shanbao Tong ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ischemic Stroke ◽  
Visible Light ◽  
Hemodynamic Response ◽  
Optical Coherence ◽  
Mouse Cortex

scholarly journals Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations

2021 ◽  
pp. 0271678X2199401
Author(s):  
Maryam Anzabi ◽  
Baoqiang Li ◽  
Hui Wang ◽  
Sreekanth Kura ◽  
Sava Sakadžić ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Capillary Flow ◽  
Hemodynamic Response ◽  
Optical Coherence ◽  
Capillary Perfusion ◽  
Pial Arteries ◽  
Primary Mechanism ◽  
Mouse Cortex ◽  
Capillary Bed ◽  
Arteriolar Diameter

Spreading depolarization (SD) is associated with profound oligemia and reduced oxygen availability in the mouse cortex during the depolarization phase. Coincident pial arteriolar constriction has been implicated as the primary mechanism for the oligemia. However, where in the vascular bed the hemodynamic response starts has been unclear. To resolve the origin of the hemodynamic response, we used optical coherence tomography (OCT) to simultaneously monitor changes in the vascular tree from capillary bed to pial arteries in mice during two consecutive SDs 15 minutes apart. We found that capillary flow dropped several seconds before pial arteriolar constriction. Moreover, penetrating arterioles constricted before pial arteries suggesting upstream propagation of constriction. Smaller caliber distal pial arteries constricted stronger than larger caliber proximal arterioles, suggesting that the farther the constriction propagates, the weaker it gets. Altogether, our data indicate that the hemodynamic response to cortical SD originates in the capillary bed.

scholarly journals Spectrally dependent roll-off in visible-light optical coherence tomography

2020 ◽  
Vol 45 (9) ◽  
pp. 2680 ◽  
Author(s):  
Ian Rubinoff ◽  
Brian Soetikno ◽  
David A. Miller ◽  
Isabella Rischall ◽  
Amani Fawzi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence

scholarly journals Visible light optical coherence tomography for retinal oximetry

2014 ◽  
Author(s):  
Ji Yi ◽  
Qing Wei ◽  
Wenzhong Liu ◽  
Vadim Backman ◽  
Hao F. Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence ◽  
Retinal Oximetry

scholarly journals Visible-light optical coherence tomography for retinal oximetry

2013 ◽  
Vol 38 (11) ◽  
pp. 1796 ◽  
Author(s):  
Ji Yi ◽  
Qing Wei ◽  
Wenzhong Liu ◽  
Vadim Backman ◽  
Hao F. Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence ◽  
Retinal Oximetry

scholarly journals Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography

2015 ◽  
Vol 6 (4) ◽  
pp. 1429 ◽  
Author(s):  
Shau Poh Chong ◽  
Conrad W. Merkle ◽  
Conor Leahy ◽  
Harsha Radhakrishnan ◽  
Vivek J. Srinivasan
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence
Sign in / Sign up

Export Citation Format

Share Document