scholarly journals Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography

2015 ◽  
Vol 6 (4) ◽  
pp. 1429 ◽  
Author(s):  
Shau Poh Chong ◽  
Conrad W. Merkle ◽  
Conor Leahy ◽  
Harsha Radhakrishnan ◽  
Vivek J. Srinivasan
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence

scholarly journals Spectrally dependent roll-off in visible-light optical coherence tomography

2020 ◽  
Vol 45 (9) ◽  
pp. 2680 ◽  
Author(s):  
Ian Rubinoff ◽  
Brian Soetikno ◽  
David A. Miller ◽  
Isabella Rischall ◽  
Amani Fawzi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence

scholarly journals Visible light optical coherence tomography for retinal oximetry

2014 ◽  
Author(s):  
Ji Yi ◽  
Qing Wei ◽  
Wenzhong Liu ◽  
Vadim Backman ◽  
Hao F. Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence ◽  
Retinal Oximetry

scholarly journals Visible-light optical coherence tomography for retinal oximetry

2013 ◽  
Vol 38 (11) ◽  
pp. 1796 ◽  
Author(s):  
Ji Yi ◽  
Qing Wei ◽  
Wenzhong Liu ◽  
Vadim Backman ◽  
Hao F. Zhang
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Optical Coherence ◽  
Retinal Oximetry

scholarly journals Retinal capillary oximetry with visible light optical coherence tomography

2020 ◽  
Vol 117 (21) ◽  
pp. 11658-11666 ◽  
Author(s):  
Shaohua Pi ◽  
Tristan T. Hormel ◽  
Xiang Wei ◽  
William Cepurna ◽  
Bingjie Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Metabolic Rate ◽  
Visible Light ◽  
Oxygen Saturation ◽  
Vascular Diseases ◽  
Retinal Vessels ◽  
Optical Coherence ◽  
Retinal Circulation ◽  
Retinal Capillary ◽  
Vascular Plexuses

Assessing oxygen saturation (sO2) remains challenging but is nonetheless necessary for understanding retinal metabolism. We and others previously achieved oximetry on major retinal vessels and measured the total retinal oxygen metabolic rate in rats using visible-light optical coherence tomography. Here we extend oximetry measurements to capillaries and investigate all three retinal vascular plexuses by amplifying and extracting the spectroscopic signal from each capillary segment under the guidance of optical coherence tomography (OCT) angiography. Using this approach, we measured capillary sO2in the retinal circulation in rats, demonstrated reproducibility of the results, validated the measurements in superficial capillaries with known perfusion pathways, and determined sO2responses to hypoxia and hyperoxia in the different retinal capillary beds. OCT capillary oximetry has the potential to provide new insights into the retinal circulation in the normal eye as well as in retinal vascular diseases.

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