scholarly journals A dual-modality digital holographic and polarization microscope to quantify phase and birefringence signals in biospecimens with complex microstructure

2022 ◽  
Author(s):  
Van Lam ◽  
Thuc Phan ◽  
Khanh Ly ◽  
Xiaolong Luo ◽  
George Nehmetallah ◽  
...  
Keyword(s):  
Dual Modality

A Novel Electrical Cpacitance Sensor Design For Dual Modality Tomography Multiphase Measurement

2013 ◽  
Vol 64 (5) ◽  
Author(s):  
Muhammad Jaysuman Pusppanathan ◽  
Fazlul Rahman Yunus ◽  
Nor Muzakkir Nor Ayob ◽  
Ruzairi Abdul Rahim ◽  
Fatin Aliah Phang ◽  
...  
Keyword(s):  
Multiphase Flow ◽  
Flow Measurement ◽  
Ultrasonic Tomography ◽  
Pipe Surface ◽  
Dual Modality ◽  
Tomography System ◽  
Imaging Result ◽  
Process Tomography ◽  
Single Sensor ◽  
Capacitance Tomography

Electrical capacitance tomography (ECT) is one of process tomography technique which is developed rapidly in recent years. ECT is an imaging technique to obtain the internal permittivity distribution of a vessel or pipe by using capacitance electrodes sensor. This method has been integrated with ultrasonic tomography as multimodality system to perform multiphase flow measurement such as crude oil separation and oil process industry. In the present paper, a novel type of ECT sensor was developed using copper FR4 material. The electrode sensors can be flexibly bend or curve to fit the pipe surface for optimum measurement. Thus, every single sensor strip is designed to be functioned independently. Such system has lower sensing capability in the central of the sensing area which often contributes to poor imaging result. This problem can be overcome by combining the ECT with ultrasonic tomography to form a dual modality tomography system. By implementing the new ECT sensor, multiphase flow measurement image results can be achieved. The reconstructed image results are presented in this paper.

Multiple-Armed Tetrahedral DNA Nanostructures for Tumor-Targeting, Dual-Modality in Vivo Imaging

2016 ◽  
Vol 8 (7) ◽  
pp. 4378-4384 ◽  
Author(s):  
Dawei Jiang ◽  
Yanhong Sun ◽  
Jiang Li ◽  
Qian Li ◽  
Min Lv ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Tumor Targeting ◽  
Dna Nanostructures ◽  
Dual Modality

scholarly journals Immunocompatibility of a new dual modality contrast agent based on radiolabeled iron-oxide nanoparticles

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria-Argyro Karageorgou ◽  
Dimosthenis Stamopoulos
Keyword(s):  
Complete Blood Count ◽  
Morphological Characteristics ◽  
Mononuclear Phagocyte ◽  
Dual Modality ◽  
Immunodeficient Mice ◽  
Force Microscopy ◽  
Magnetic Resonance Imaging Mri ◽  
Diagnostic Applications

AbstractRadiolabeled magnetic nanoparticles are promising candidates as dual-modality-contrast-agents (DMCA) for diagnostic applications. The immunocompatibility of a new DMCA is a prerequisite for subsequent in vivo applications. Here, a new DMCA, namely Fe3O4 nanoparticles radiolabeled with 68Ga, is subjected to immunocompatibility tests both in vitro and in vivo. The in vitro immunocompatibility of the DMCA relied on incubation with donated human WBCs and PLTs (five healthy individuals). Optical microscopy (OM) and atomic force microscopy (AFM) were employed for the investigation of the morphological characteristics of WBCs and PLTs. A standard hematology analyzer (HA) provided information on complete blood count. The in vivo immunocompatibility of the DMCA was assessed through its biodistribution among the basic organs of the mononuclear phagocyte system in normal and immunodeficient mice (nine in each group). In addition, Magnetic Resonance Imaging (MRI) data were acquired in normal mice (three). The combined OM, AFM and HA in vitro data showed that although the DMCA promoted noticeable activation of WBCs and PLTs, neither degradation nor clustering were observed. The in vivo data showed no difference of the DMCA biodistribution between the normal and immunodeficient mice, while the MRI data prove the efficacy of the particular DMCA when compared to the non-radiolabeled, parent CA. The combined in vitro and in vivo data prove that the particular DMCA is a promising candidate for future in vivo applications.

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