scholarly journals In-Vitro Study on Identification of Gastrointestinal Stromal Tumor Tissues using Laser-Induced Breakdown Spectroscopy with Chemometric Methods

2021 ◽  
Author(s):  
BUSHRA IDREES ◽  
Qianqian Wang ◽  
M. Nouman Khan ◽  
Geer Teng ◽  
Xutai Cui ◽  
...  
2018 ◽  
Vol 10 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Aida Seifalinezhad ◽  
Maryam Bahreini ◽  
Mohammad Mahdi Hassani Matin ◽  
Seyed Hassan Tavassoli

Introduction: The present work is a novel in vitro study that evaluated the possibility of diagnosing neoplastic from nonneoplastic gastric tissues using spark discharge assisted laser induced breakdown spectroscopy (SD-LIBS) method. Methods: In these experiments, the low energy laser pulses ablated a tiny amount of tissue surface leading to plasma formation. Then, a spark discharge was applied to plasma in order to intensify the plasma radiation. Light emission from plasma was recorded as spectra which were analyzed. Gastric tissues of 5 people were studied through this method. Results: The SD-LIBS technique had the potential to discriminate normal and cancerous tissues based on the significant differences in the intensities of some particular elements. The comparison of normalized calcium (Ca) and magnesium (Mg) peaks of neoplastic and nonneoplastic gastric tissues could be viewed as a practical measure for tissue discrimination since Ca and Mg peaks in spectra of neoplastic were noticeably higher than nonneoplastic. Conclusion: Considering the identification of gastric cancer, the applied method in these experiments seems quite fast, noninvasive and cost-effective with respect to other conventional methods. The significant increment of specific Ca and Mg lines of neoplastic gastric tissues in comparison to the nonneoplastic ones can be considered as valuable information that might bring about tissue classification. The number of samples in this work, however, was not sufficient for a decisive conclusion and further researches is needed to generalize this idea.


2016 ◽  
Vol 31 (8) ◽  
pp. 302-310 ◽  
Author(s):  
Achim Paulmichl ◽  
Dominik Summer ◽  
Claudia Manzl ◽  
Christine Rangger ◽  
Francesca Orlandi ◽  
...  

2020 ◽  
Vol 22 (7) ◽  
pp. 074012 ◽  
Author(s):  
Zhongqi FENG ◽  
Dacheng ZHANG ◽  
Bowen WANG ◽  
Jie DING ◽  
Xuyang LIU ◽  
...  

2018 ◽  
Vol 57 (28) ◽  
pp. 8297 ◽  
Author(s):  
Ping Yang ◽  
Ran Zhou ◽  
Wen Zhang ◽  
Shisong Tang ◽  
Zhongqi Hao ◽  
...  

2007 ◽  
Vol 22 (12) ◽  
pp. 1471 ◽  
Author(s):  
Jean-Baptiste Sirven ◽  
Béatrice Sallé ◽  
Patrick Mauchien ◽  
Jean-Luc Lacour ◽  
Sylvestre Maurice ◽  
...  

2020 ◽  
Vol 12 (27) ◽  
pp. 3530-3536
Author(s):  
Youjian Zhang ◽  
Zhang Xiong ◽  
Yiwen Ma ◽  
Chenwei Zhu ◽  
Ran Zhou ◽  
...  

LIBS technique assisted with four different chemometric methods was applied to rapid and accurate measurement of coal quality, and the modeling efficiency and prediction accuracy of the four calibration methods were compared and discussed.


The Analyst ◽  
2021 ◽  
Author(s):  
Fangqi Ruan ◽  
Lin Hou ◽  
Tianlong Zhang ◽  
Hua Li

Laser-induced breakdown spectroscopy (LIBS) has been appreciated as a valuable analytical tool in the cultural heritage field owing to its unique technological superiority, particularly in combination with chemometric methods.


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