Application of the maximum entropy method to spectral-domain optical coherence tomography for enhancing axial resolution

2007 ◽  
Vol 46 (22) ◽  
pp. 5228 ◽  
Author(s):  
Yoshiyuki Takahashi ◽  
Yuuki Watanabe ◽  
Manabu Sato
Keyword(s):  
Optical Coherence Tomography ◽  
Maximum Entropy ◽  
Maximum Entropy Method ◽  
Entropy Method ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Axial Resolution

scholarly journals Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography

Electronics ◽  
2018 ◽  
Vol 7 (9) ◽  
pp. 182 ◽  
Author(s):  
Sangyeob Han ◽  
Oeon Kwon ◽  
Ruchire Wijesinghe ◽  
Pilun Kim ◽  
Unsang Jung ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Real Time ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Axial Resolution ◽  
Dependent Signal ◽  
Nonlinear Sampling ◽  
Time Linear ◽  
Optical Laser ◽  
Sd Oct

An index-regulation technique functionalized by numerical sampling for direct calibration of the non-linear wavenumber (k)-domain to a linear domain in spectral domain optical coherence tomography (SD-OCT) is proposed. The objective of the developed method is to facilitate high-resolution identification of microstructures in biomedical imaging. Subjective optical alignments caused by nonlinear sampling of interferograms in the k-domain tend to hinder depth-dependent signal-to-noise ratios (SNR) and axial resolution in SD-OCT. Moreover, the optical-laser-dependent k-domain requires constant recalibrated in accordance with each laser transition, thereby necessitating either hardware or heavy software compensations. As the key feature of the proposed method, a relatively simple software-based k-domain mask calibration technique was developed to enable real-time linear sampling of k-domain interpolations whilst facilitating image observation through use of an index-regulation technique. Moreover, it has been confirmed that dispersion can be simultaneously compensated with noise residuals generated using the proposed technique, and that use of complex numerical or hardware techniques are no longer required. Observed results, such as fall-off, SNR, and axial resolution clearly exhibit the direct impact of the proposed technique, which could help investigators rapidly achieve optical-laser-independent high-quality SD-OCT images.

scholarly journals Optimization for Axial Resolution, Depth Range, and Sensitivity of Spectral Domain Optical Coherence Tomography at 1.3 ¥ìm

2009 ◽  
Vol 55 (6) ◽  
pp. 2354-2360 ◽  
Author(s):  
Sang-Won Lee ◽  
Hyun-Woo Jeong ◽  
Yeh-Chan Ahn ◽  
Woonggyu Jung ◽  
Zhongping Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Depth Range ◽  
Optical Coherence ◽  
Axial Resolution

scholarly journals Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated circuit-based arrayed waveguide gratings

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Elisabet A. Rank ◽  
Ryan Sentosa ◽  
Danielle J. Harper ◽  
Matthias Salas ◽  
Anna Gaugutz ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Integrated Circuit ◽  
Three Dimensional ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Arrayed Waveguide Grating ◽  
Axial Resolution ◽  
Waveguide Grating ◽  
Arrayed Waveguide

AbstractIn this work, we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip. The diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide grating. Two arrayed waveguide grating designs with 256 channels were tested, which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal measurements. Design 1 supports a bandwidth of 22 nm, with which a sensitivity of up to 91 dB (830 µW) and an axial resolution of 10.7 µm was measured. Design 2 supports a bandwidth of 48 nm, with which a sensitivity of 90 dB (480 µW) and an axial resolution of 6.5 µm was measured. The silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process, which allows their monolithic co-integration on top of an optoelectronic silicon chip. As a benchmark for chip-based optical coherence tomography, tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip gratings. The similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.

Axial resolution and depth range of high-resolution spectral domain optical coherence tomography at 1.3 μm

2009 ◽  
Author(s):  
Sang-Won Lee ◽  
Hyun-Woo Jeong ◽  
Yeh-Chan Ahn ◽  
Woonggyu Jung ◽  
Zhongping Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Spectral Domain ◽  
Depth Range ◽  
Optical Coherence ◽  
Axial Resolution

scholarly journals Interferometer-in-Spectrometer for High-Resolution Optical Coherence Tomography

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Lishuang Liu ◽  
Jun Xie ◽  
Linbo Liu ◽  
Si Chen
Keyword(s):  
Optical Coherence Tomography ◽  
Imaging System ◽  
Ex Vivo ◽  
Biological Tissues ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Axial Resolution ◽  
Testing Method ◽  
Spectral Domain Oct ◽  
Standard Design

Ultrahigh-resolution optical coherence tomography provides an axial resolution of 1-2 μm for resolving cellular structures of biological tissues critical for the diagnosis of diseases. However, it requires a relatively large spectral bandwidth which is not supported by the key components of the imaging system. We propose a novel spectral-domain OCT design, termed interferometer-in-spectrometer, which is able to compensate the bandwidth limitations of the grating and the line scan sensor by spectral shaping without compromising the signal intensity and adding the system cost. The advantage of axial resolution and ranging depth over the standard design is experimentally validated using the standard testing method and fresh swine cornea ex vivo. Moreover, opportunities that opened up by this new scheme for improving the performances of spectral-domain OCT are also discussed.

Sign in / Sign up

Export Citation Format

Share Document