A high speed three-dimensional spectral domain optical coherence tomography with <2 μm axial resolution using wide bandwidth femtosecond mode-locked laser

2013 ◽  
Vol 102 (25) ◽  
pp. 251102 ◽  
Author(s):  
Hiroto Kuroda ◽  
Motoyoshi Baba ◽  
Masayuki Suzuki ◽  
Shin Yoneya
2007 ◽  
Vol 15 (12) ◽  
pp. 7103 ◽  
Author(s):  
Yoshifumi Nakamura ◽  
Shuichi Makita ◽  
Masahiro Yamanari ◽  
Masahide Itoh ◽  
Toyohiko Yatagai ◽  
...  

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Elisabet A. Rank ◽  
Ryan Sentosa ◽  
Danielle J. Harper ◽  
Matthias Salas ◽  
Anna Gaugutz ◽  
...  

AbstractIn this work, we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip. The diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide grating. Two arrayed waveguide grating designs with 256 channels were tested, which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal measurements. Design 1 supports a bandwidth of 22 nm, with which a sensitivity of up to 91 dB (830 µW) and an axial resolution of 10.7 µm was measured. Design 2 supports a bandwidth of 48 nm, with which a sensitivity of 90 dB (480 µW) and an axial resolution of 6.5 µm was measured. The silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process, which allows their monolithic co-integration on top of an optoelectronic silicon chip. As a benchmark for chip-based optical coherence tomography, tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip gratings. The similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.


2005 ◽  
Author(s):  
Erich Goetzinger ◽  
Michael Pircher ◽  
Rainer A. Leitgeb ◽  
Adolf F. Fercher ◽  
Christoph K. Hitzenberger

2014 ◽  
Vol 41 (7) ◽  
pp. 0704001 ◽  
Author(s):  
王玲 Wang Ling ◽  
朱海龙 Zhu Hailong ◽  
涂沛 Tu Pei ◽  
吴开华 Wu Kaihua

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