Multi-Spectral Optoacoustic Tomography - Next Generation Platform for High Resolution Imaging of Diffuse Tissues

Author(s):  
Daniel Razansky ◽  
Vasilis Ntziachristos
2012 ◽  
Author(s):  
Stefan Morscher ◽  
Nikolaos C. Deliolanis ◽  
Neal C. Burton ◽  
Karin Schaefer ◽  
Daniel Razansky ◽  
...  

2020 ◽  
Author(s):  
Andrzej Górszczyk ◽  
Stéphane Operto

Abstract. Detailed reconstruction of deep crustal targets by seismic methods remains a long-standing challenge. One key to address this challenge is the joint development of new seismic acquisition systems and leading-edge processing techniques. In marine environments, controlled-source seismic surveys at regional scale are typically carried out with sparse arrays of ocean bottom seismometers (OBSs), which provide incomplete and down-sampled subsurface illumination. To assess and minimize the acquisition footprint in high-resolution imaging process such as full waveform inversion, realistic crustal-scale benchmark models are clearly required.The deficiency of such models prompts us to build one and release it freely to the geophysical community. Here we introduce GO_3D_OBS – a 3D high-resolution geomodel representing a subduction zone, inspired by the geology of the Nankai Trough. The 175 km x 100 km x 30 km model integrates complex geological structures with a visco-elastic isotropic parametrization. It is defined in form of a uniform Cartesian grid containing 33.6e9 degrees of freedom for a grid interval of 25 m. The size of the model raises significant high-performance computing challenges to tackle large-scale forward propagation simulations and related inverse problems. We describe the workflow designed to implement all the model ingredients including 2D structural segments, their projection into the third dimension, stochastic components and physical parametrisation. Various wavefield simulations we present clearly reflect in the seismograms the structural complexity of the model and the footprint of different physical approximations. This benchmark model shall help to optimize the design of next generation 3D academic surveys – in particular but not only long-offset OBS experiments – to mitigate the acquisition footprint during high-resolution imaging of the deep crust.


2021 ◽  
Vol 14 (3) ◽  
pp. 1773-1799
Author(s):  
Andrzej Górszczyk ◽  
Stéphane Operto

Abstract. Detailed reconstruction of deep crustal targets by seismic methods remains a long-standing challenge. One key to address this challenge is the joint development of new seismic acquisition systems and leading-edge processing techniques. In marine environments, controlled-source seismic surveys at a regional scale are typically carried out with sparse arrays of ocean bottom seismometers (OBSs), which provide incomplete and down-sampled subsurface illumination. To assess and minimize the acquisition footprint in high-resolution imaging process such as full waveform inversion, realistic crustal-scale benchmark models are clearly required. The deficiency of such models prompts us to build one and release it freely to the geophysical community. Here, we introduce GO_3D_OBS – a 3D high-resolution geomodel representing a subduction zone, inspired by the geology of the Nankai Trough. The 175km×100km×30km model integrates complex geological structures with a viscoelastic isotropic parameterization. It is defined in the form of a uniform Cartesian grid containing ∼33.6e9 degrees of freedom for a grid interval of 25 m. The size of the model raises significant high-performance computing challenges to tackle large-scale forward propagation simulations and related inverse problems. We describe the workflow designed to implement all the model ingredients including 2D structural segments, their projection into the third dimension, stochastic components, and physical parameterization. Various wavefield simulations that we present clearly reflect in the seismograms the structural complexity of the model and the footprint of different physical approximations. This benchmark model is intended to help to optimize the design of next-generation 3D academic surveys – in particular, but not only, long-offset OBS experiments – to mitigate the acquisition footprint during high-resolution imaging of the deep crust.


Author(s):  
Andreas Eckardt ◽  
Stefan Gläsener ◽  
Ralf Reulke ◽  
Karsten Sengebusch ◽  
Bernd Zender

Author(s):  
J.M. Cowley

By extrapolation of past experience, it would seem that the future of ultra-high resolution electron microscopy rests with the advances of electron optical engineering that are improving the instrumental stability of high voltage microscopes to achieve the theoretical resolutions of 1Å or better at 1MeV or higher energies. While these high voltage instruments will undoubtedly produce valuable results on chosen specimens, their general applicability has been questioned on the basis of the excessive radiation damage effects which may significantly modify the detailed structures of crystal defects within even the most radiation resistant materials in a period of a few seconds. Other considerations such as those of cost and convenience of use add to the inducement to consider seriously the possibilities for alternative approaches to the achievement of comparable resolutions.


Author(s):  
Max T. Otten ◽  
Wim M.J. Coene

High-resolution imaging with a LaB6 instrument is limited by the spatial and temporal coherence, with little contrast remaining beyond the point resolution. A Field Emission Gun (FEG) reduces the incidence angle by a factor 5 to 10 and the energy spread by 2 to 3. Since the incidence angle is the dominant limitation for LaB6 the FEG provides a major improvement in contrast transfer, reducing the information limit to roughly one half of the point resolution. The strong improvement, predicted from high-resolution theory, can be seen readily in diffractograms (Fig. 1) and high-resolution images (Fig. 2). Even if the information in the image is limited deliberately to the point resolution by using an objective aperture, the improved contrast transfer close to the point resolution (Fig. 1) is already worthwhile.


Author(s):  
Xiao Zhang

Electron holography has recently been available to modern electron microscopy labs with the development of field emission electron microscopes. The unique advantage of recording both amplitude and phase of the object wave makes electron holography a effective tool to study electron optical phase objects. The visibility of the phase shifts of the object wave makes it possible to directly image the distributions of an electric or a magnetic field at high resolution. This work presents preliminary results of first high resolution imaging of ferroelectric domain walls by electron holography in BaTiO3 and quantitative measurements of electrostatic field distribution across domain walls.


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