Total Immersion: An Interview with Allegra Goodman

MELUS ◽  
2012 ◽  
Vol 37 (4) ◽  
pp. 187-202 ◽  
Author(s):  
Lori Harrison-Kahan
2021 ◽  
pp. 152808372199746
Author(s):  
Tittaya Thairin ◽  
Patcharaporn Wutticharoenmongkol

Herein, ciprofloxacin (CIP)-loaded alginate/poly (vinyl alcohol)/gelatin (SPG) (CIP–SPG) nanofiber mats were successfully fabricated by electrospinning. The average fiber diameters of the mats before and after crosslinking were in the range of 190–260 and 385–484 nm, respectively. The chemical integrity of CIP remained intact after encapsulation into the mats. The degree of weight loss and water swelling decreased with an increase in the gelatin content of the electrospun nanofiber mats. A release study was carried out by total immersion and diffusion methods using phosphate buffer as a release medium. Burst release of CIP was observed in case of the total immersion method, while a more sustained release was observed in case of the diffusion method. The maximum amounts of CIP released during total immersion and diffusion were in the range of 70–90% and 72–85%, respectively. For both the total immersion and diffusion methods, the released amounts of CIP decreased and the release slowed down with an increase in the gelatin content; this result is consistent with the weight loss and water swelling values. The Young’s modulus increased, while the tensile strength and strain at break decreased with an increase in the gelatin content. The CIP–SPG nanofiber mats were slightly toxic to L929 mouse fibroblasts as evaluated by indirect cytotoxicity assay. The electrospun CIP–SPG nanofiber mats exhibited excellent antimicrobial activity against Staphylococcus aureus and Escherichia coli. These results reveal that the electrospun CIP–SPG nanofiber mats are potentially promising materials for wound healing applications.


2014 ◽  
Vol 224 (3000-3001) ◽  
pp. 27
Author(s):  
Aviva Rutkin
Keyword(s):  

Opflow ◽  
1975 ◽  
Vol 1 (2) ◽  
pp. 1-2
Author(s):  
Willard Reese ◽  
George Cathcart
Keyword(s):  

Tempo ◽  
2009 ◽  
Vol 63 (249) ◽  
pp. 52-67

Munich: Ben-Haim's ‘Joram’ Malcolm MillerLos Angeles: Andriessen's ‘The Hague Hacking’ Jeff DunnNew York: Kirchner 90th Birthday Celebrations Christian CareyMilton Keynes: Wood's Violin Concerto No. 2 Edward VennTewkesbury: Christopher Steel Paul ConwayLondon, Barbican: ‘Total Immersion’ Days John WheatleyLeeds: David Sawer's ‘Skin Deep’ Paul ConwayOpera premières in London Martin Anderson, Malcolm MillerFurther reports from London and St Albans Jill Barlow, Paul Conway, John Wheatley


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