Haplotype Distribution of and Linkage Disequilibrium Between Four Polymorphic Markers Near the CFTR Locus in Brazilian Cystic Fibrosis Patients

Human Biology ◽  
2005 ◽  
Vol 77 (6) ◽  
pp. 853-865 ◽  
Author(s):  
Giselda M. K. Cabello ◽  
Pedro H. Cabello ◽  
Jorge S. Lopez-Camelo ◽  
Juan C. Llerena ◽  
Octavio Fernandes
Keyword(s):  
Cystic Fibrosis ◽  
Linkage Disequilibrium ◽  
Polymorphic Markers ◽  
Haplotype Distribution

scholarly journals Homozygosity and Linkage Disequilibrium

Genetics ◽  
2002 ◽  
Vol 160 (4) ◽  
pp. 1707-1719
Author(s):  
Chiara Sabatti ◽  
Neil Risch
Keyword(s):  
Phase Equilibrium ◽  
Linkage Disequilibrium ◽  
Specific Form ◽  
Polymorphic Markers ◽  
Biological Interpretation ◽  
Gametic Phase

Abstract We illustrate how homozygosity of haplotypes can be used to measure the level of disequilibrium between two or more markers. An excess of either homozygosity or heterozygosity signals a departure from the gametic phase equilibrium: We describe the specific form of dependence that is associated with high (low) homozygosity and derive various linkage disequilibrium measures. They feature a clear biological interpretation, can be used to construct tests, and are standardized to allow comparison across loci and populations. They are particularly advantageous to measure linkage disequilibrium between highly polymorphic markers.

Linkage disequilibrium for DNA haplotypes near the cystic fibrosis locus in two South European populations

1989 ◽  
Vol 83 (2) ◽  
pp. 175-178 ◽  
Author(s):  
X. Estivill ◽  
P. Gasparini ◽  
G. Novelli ◽  
T. Casals ◽  
V. Nunes ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Linkage Disequilibrium ◽  
European Populations

Analysis of linkage disequilibrium between different cystic fibrosis mutations and three intragenic microsatellites in the Italian population

1995 ◽  
Vol 5 (1) ◽  
pp. 23-27 ◽  
Author(s):  
Maria Pia Russo ◽  
Giovanni Romeo ◽  
Marcella Devoto ◽  
Guido Barbujani ◽  
Giulio Cabrini ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Linkage Disequilibrium ◽  
Italian Population

scholarly journals O-075. Multiplex PCR of polymorphic markers flanking the CFTR gene: a general approach for pre-implantation genetic diagnosis of cystic fibrosis

1999 ◽  
Vol 14 (Suppl_3) ◽  
pp. 41-42 ◽  
Author(s):  
J.C.F.M. Dreesen ◽  
L.J.A.M. Jacobs ◽  
M. Bras ◽  
H.J.M. Smeets ◽  
J. Herbergs ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Multiplex Pcr ◽  
Genetic Diagnosis ◽  
Cftr Gene ◽  
Polymorphic Markers

Linkage studies between polymorphic markers on chromosome 4 and cystic fibrosis

1985 ◽  
Vol 69 (3) ◽  
pp. 250-254 ◽  
Author(s):  
P. Scambler ◽  
T. Robbins ◽  
C. Gilliam ◽  
A. Boylston ◽  
P. Tippett ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Polymorphic Markers ◽  
Chromosome 4 ◽  
Linkage Studies

Patterns of polymorphism and linkage disequilibrium for cystic fibrosis

Genomics ◽  
1987 ◽  
Vol 1 (3) ◽  
pp. 257-263 ◽  
Author(s):  
X. Estivill ◽  
P.J. Scambler ◽  
B.J. Wainwright ◽  
K. Hawley ◽  
P. Frederick ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Linkage Disequilibrium

The haplotype distribution of the ΔF508 mutation in cystic fibrosis families in Scotland

1990 ◽  
Vol 85 (4) ◽  
pp. 419-420 ◽  
Author(s):  
Iain McIntosh ◽  
Ann Curtis ◽  
Maria-Luz Lorenzo ◽  
Marion Keston ◽  
Annette J. Gilfillan ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Haplotype Distribution

Linkage disequilibrium and haplotype distribution of the bovine LHX4 gene in relation to growth

Gene ◽  
2014 ◽  
Vol 538 (2) ◽  
pp. 354-360 ◽  
Author(s):  
Gang Ren ◽  
Yong-Zhen Huang ◽  
Tian-Bao Wei ◽  
Jun-Xia Liu ◽  
Xian-Yong Lan ◽  
...  
Keyword(s):  
Linkage Disequilibrium ◽  
Haplotype Distribution

scholarly journals The genetic background of osteoporosis in cystic fibrosis: Association analysis with polymorphic markers in four candidate genes

2006 ◽  
Vol 5 (4) ◽  
pp. 229-235 ◽  
Author(s):  
Carlo Castellani ◽  
Giovanni Malerba ◽  
Antonella Sangalli ◽  
Antonella Delmarco ◽  
Elena Petrelli ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Candidate Genes ◽  
Association Analysis ◽  
Genetic Background ◽  
Polymorphic Markers
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