scholarly journals A Review on Medicinal Constituents and Therapeutic Potential of Moringa oleifera

2020 ◽  
Vol 8 (2) ◽  
pp. 22-33
Author(s):  
Mitali Srivastava ◽  
Prashant K Dhakad ◽  
Birendra Srivastava
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential

scholarly journals How Functional Is Moringa oleifera? A Review of Its Nutritive, Medicinal, and Socioeconomic Potential

2017 ◽  
Vol 39 (1) ◽  
pp. 149-170 ◽  
Author(s):  
Oluwadara Oluwaseun Alegbeleye
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Scientific Evidence ◽  
Popular Literature ◽  
Scientific Data ◽  
Personal Health ◽  
Health Food ◽  
Self Medication ◽  
Developing Regions ◽  
Dietary Consumption

Moringa oleifera is an important tropical food plant that seems to have great nutritional, therapeutic, industrial, agricultural, and socioeconomic value. Dietary consumption of its parts and preparations is encouraged by several organizations, health food enthusiasts, and other specialists as a strategy of personal health preservation and self-medication in the treatment of various diseases. Studies extoling its ability to mitigate various degenerative ailments now exist in both the scientific and the popular literature. At face value, and considering the volume of reports available, much of this enthusiasm seems to be indeed justified. However, it is imperative to distinguish rigorous scientific evidence from anecdote. To achieve this, relevant experimental and review articles were sought and read critically to identify recent patterns and trends on this subject matter. Studies on the medicinal and functional properties of M. oleifera are available from various parts of the world, especially developing regions. Attempts have been made to parse the contemporary scientific data available supporting the claims regarding the phytochemical, nutritive, medicinal, environmental, agricultural, and socioeconomic capabilities of this plant. Studies reviewed provide compelling, albeit preliminary experimental evidence of therapeutic potential of the plant. It is important that M. oleifera products and preparations be properly chemically characterized and standardized before being administered.

scholarly journals VALIDATION OF TRIBAL CLAIMS ON MORINGA OLEIFERA LAM. USING PHYTOCHEMICAL ANALYSIS

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Getsial Sabatini Wallace J ◽  
S. Naveen Kumar ◽  
V. Negasta Smila ◽  
T. Nivitha ◽  
Stalin Nithaniyal ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Future Research ◽  
Phytochemical Analysis ◽  
Traditional Use ◽  
Phytochemical Study ◽  
Medicinal Uses ◽  
Pharmacological Significance ◽  
History Of

Moringa is a medicinally important genus that has long history of traditional use as a remedy to cure wounds and various ailments such as colds, diabetes, digestive problems etc. In addition, the species is consumed as a source of nutritive food and used as vegetables worldwide. The genus consists of 13 species that have been cultivated throughout Asia and Africa for their multiple purpose use value. The current study is aimed to validate the traditional medicinal uses of Moringa oleifera, provide scientific insights on the phytochemistry, biological activities and thereby correlating its therapeutic potential for future prospects. Analysis of phytochemical profile showed the presence of the major important bioactive compounds (saponin, tannin, flavonoids, phenolics, and reducing sugar) that were assessed in aqueous, methanolic aqueous and acetone-aqueous extracts following standard procedures. This study provides the foundation to explore the tribal medicinal use complemented with the scientific evaluation. Our study reinforce further phytochemical study with advanced technologies for future research opportunities of this species as it is an interesting plant containing commercially important active compounds that enable to determine pharmacological significance, and socio-economic potential.

scholarly journals A REVIEW ON NUTRITIONAL AND MEDICINAL IMPORTANCE OF SHIGRU LEAVES (Moringa oleifera Lam) AND PUNARNAVA (Boerhavia diffusa L. nom.cons.)

2021 ◽  
Vol 09 (3) ◽  
pp. 608-614
Author(s):  
Lakshmi Divya. M ◽  
Madhusudana Rao. K ◽  
Suguna Jyothy. P
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Leafy Vegetables ◽  
Nutritional Properties ◽  
Nutritional Values ◽  
Dietary Practice ◽  
Therapeutic Uses ◽  
Boerhavia Diffusa ◽  
Moringa Oleifera Lam

Across classical texts of Ayurveda detailed description of different vegetables are mentioned under Shaka varga. The nutritional properties, therapeutic uses and indications of Patra (Leafy vegetables), Pushpa (Flowering vegetables), Phala (Fruiting vegetables), Nala (Stalked vegetables), Kanda (Tuber vegetables) are delineated in Shaka varga. Only a few among these vegetables are being used in day-to-day practice, the reason might be due to the lack of availability or lack of awareness about the nutritional values and therapeutic potential. This article is focused to show the potentiality of Shigru (Moringa oleifera Lam) pa-tra and Punarnava (Boerhavia diffusa L. nom.cons.) which are under-utilised in today’s dietary practice even they are abundantly available.

scholarly journals Anticancer Potential of Moringa oleifera on BRCA-1 Gene: Systems Biology

2021 ◽  
Vol 15 ◽  
pp. 117793222110107
Author(s):  
Toheeb A Balogun ◽  
Kaosarat D Buliaminu ◽  
Onyeka S Chukwudozie ◽  
Zainab A Tiamiyu ◽  
Taiwo J Idowu
Keyword(s):  
Breast Cancer ◽  
Anticancer Agents ◽  
Active Site ◽  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Pharmacokinetic Parameters ◽  
Ligand Interaction ◽  
Continuous Increase ◽  
Drug Candidates ◽  
Brca 1

Breast cancer has consistently been a global challenge that is prevalent among women. There is a continuous increase in the high number of women mortality rates because of breast cancer and affecting nations at all modernization levels. Women with high-risk factors, including hereditary, obesity, and menopause, have the possibility of developing breast cancer growth. With the advent of radiotherapy, chemotherapy, hormone therapy, and surgery in breast cancer treatment, breast cancer survivors have increased. Also, the design and development of drugs targeting therapeutic enzymes effectively treat the tumour cells early. However, long-term use of anticancer drugs has been linked to severe side effects. This research aims to develop potential drug candidates from Moringa oleifera, which could serve as anticancer agents. In silico analysis using Schrödinger Molecular Drug Discovery Suite and SWISS ADME was employed to determine the therapeutic potential of phytochemicals from M oleifera against breast cancer via molecular docking, pharmacokinetic parameters, and drug-like properties. The result shows that rutin, vicenin-2, and quercetin-3-O-glucoside have the highest binding energy of −7.522, −6.808, and −6.635 kcal/mol, respectively, in the active site of BRCA-1. The essential amino acids involved in the protein-ligand interaction following active site analysis are ASN 1678, ASN 1774, GLY 1656, LEU 1657, GLN 1779, LYS 1702, SER 1655, PHE 1662, ARG 1699, GLU 1698, and VAL 1654. Thus, we propose that bioactive compounds from M oleifera may be potential novel drug candidates in the treatment of breast cancer.

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