Optimal Position of Ion Source for High Performance of IEC

2005 ◽  
Vol 47 (4) ◽  
pp. 1265-1269 ◽  
Author(s):  
Hodaka Osawa ◽  
Takayuki Ishibashi ◽  
Masami Ohnishi ◽  
Kiyoshi Yoshikawa
Keyword(s):  
High Performance ◽  
Ion Source ◽  
Optimal Position

scholarly journals Optimization of Dynamic Task Location within a Manipulator’s Workspace for the Utilization of the Minimum Required Joint Torques

Electronics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 288
Author(s):  
Adam Wolniakowski ◽  
Charalampos Valsamos ◽  
Kanstantsin Miatliuk ◽  
Vassilis Moulianitis ◽  
Nikos Aspragathos
Keyword(s):  
High Performance ◽  
Human Robot Interaction ◽  
Optimal Position ◽  
End Effector ◽  
Joint Torques ◽  
Dynamic Task ◽  
Arbitrary Position ◽  
Simulation Results ◽  
Set Up ◽  
Task Placement

The determination of the optimal position of a robotic task within a manipulator’s workspace is crucial for the manipulator to achieve high performance regarding selected aspects of its operation. In this paper, a method for determining the optimal task placement for a serial manipulator is presented, so that the required joint torques are minimized. The task considered comprises the exercise of a given force in a given direction along a 3D path followed by the end effector. Given that many such tasks are usually conducted by human workers and as such the utilized trajectories are quite complex to model, a Human Robot Interaction (HRI) approach was chosen to define the task, where the robot is taught the task trajectory by a human operator. Furthermore, the presented method considers the singular free paths of the manipulator’s end-effector motion in the configuration space. Simulation results are utilized to set up a physical execution of the task in the optimal derived position within a UR-3 manipulator’s workspace. For reference the task is also placed at an arbitrary “bad” location in order to validate the simulation results. Experimental results verify that the positioning of the task at the optimal location derived by the presented method allows for the task execution with minimum joint torques as opposed to the arbitrary position.

Optimal Static Characteristics of Amphibious PAR Vehicles

2008 ◽  
Vol 130 (3) ◽  
Author(s):  
Konstantin I. Matveev
Keyword(s):  
Water Surface ◽  
High Performance ◽  
Static Friction ◽  
Solid Surfaces ◽  
Vertical Position ◽  
Optimal Position ◽  
Optimal Values ◽  
Jet Theory ◽  
New Generation ◽  
The Ideal

Power augmented ram platform vehicle is a high-performance air-assisted amphibious transport of the new generation. The objective of this study is to determine the optimal position of the platform flap for low-speed operations on water and solid ground. The static friction of vehicle hulls on solid surfaces and the static deformation of the water surface are combined with results of the ideal jet theory to predict forces and the platform position. The optimal values for the flap gap are obtained that maximize the recovered static thrust on solid surfaces and the vehicle vertical position on the water surface.

High Performance Heavy-Ion Source for Cyclotrons

1971 ◽  
Vol 18 (3) ◽  
pp. 113-117 ◽  
Author(s):  
E. D. Hudson ◽  
M. L. Mallory ◽  
S. W. Mosko
Keyword(s):  
High Performance ◽  
Heavy Ion ◽  
Ion Source

LC-MS/MS based targeted metabolomics method for analysis of serum and cerebrospinal fluid

2019 ◽  
Vol 88 (1) ◽  
pp. 12-20
Author(s):  
Szymon Plewa ◽  
Paweł Dereziński ◽  
Jolanta Florczak-Wyspiańska ◽  
Karolina Popławska-Domaszewicz ◽  
Wojciech Kozubski ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
High Performance ◽  
Ion Source ◽  
Low Molecular Weight ◽  
Successful Implementation ◽  
Tandem Mass ◽  
Triple Quadrupole ◽  
Targeted Metabolomics ◽  
The Mean ◽  
Liquid Chromatography System

Introduction. Recent instrumentation and software advancement enabled to develop new, high‑throughput targeted metabolomics methods for in‑depth exploration of metabolome in a quantitative manner.Material and Methods. The presented targeted metabolomics approach allows to analyze both of serum and CSF in the same way, with identical sample preparation procedures. The analyses were carried out using high‑performance liquid chromatography system coupled to triple quadrupole tandem mass spectrometer with electrospray ion source (LC‑ESI‑QqQ‑MS/MS). Results. The applied targeted metabolomics approach enabled to determine a wide panel of metabolites from different chemical classes of compounds including: acylcarnitines, amino acids and biogenic amines, glycerophospholipids, sphingolipids and sum of hexoses. Finally, 148 metabolites in serum and 57 in cerebrospinal fluid were determined.Conclusions. Here we presented the results of successful implementation of the method of analysis of low‑molecular weight compounds in human serum and CSF using targeted metabolomics. The evaluation of selected groups of metabolites resulted in obtaining the mean concentrations of panel of metabolites in serum and CSF, which gives a valuable information about the metabolome of these matrices.

scholarly journals Simultaneous Determination and Pharmacokinetics Study of Six Triterpenes in Rat Plasma by UHPLC-MS/MS after Oral Administration of Sanguisorba officinalis L. Extract

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2980 ◽  
Author(s):  
Chengcui Wu ◽  
Meicun Yao ◽  
Wa Li ◽  
Binbin Cui ◽  
Hongrui Dong ◽  
...  
Keyword(s):  
Oral Administration ◽  
High Performance ◽  
Multiple Reaction Monitoring ◽  
Internal Standard ◽  
Current Method ◽  
Rat Plasma ◽  
Ion Source ◽  
Pharmacokinetics Study ◽  
Liquid Chromatography Tandem Mass ◽  
Sanguisorba Officinalis

A selective and sensitive ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed and validated for the determination of ziyuglycoside I (I), 3β,19α-dihydroxyurs-12-en-28-oic-acid 28-β-d-glucopyranosyl ester (II), 3β-[(α-l-arabinopyranosyl) oxy]-urs-12,18(19)-dien-28-oic acid β-d-glucopyranosyl ester (III), rosamultin (IV), 1β-hydroxyeuscaphic acid (V) and alpinoside (VI) in rats after oral administration of Sanguisorba officinalis L. (S. officinalis) extract. The 3β,19α-dihydroxyurs-12-en-28-oic-acid 28-β-d-glucopyranosyl ester, 3β-[(α-l-arabinopyranosyl) oxy]-urs-12,18(19)-dien-28-oic acid β-d-glucopyranosyl ester, rosamultin, 1β-hydroxyeuscaphic acid and alpinoside in rat plasma were the first report in the pharmacokinetics study in the present study. The analytes were quantified using the multiple reaction monitoring (MRM) mode with the electrospray ion source in positive electrospray ionization. Plasma was extracted with ethyl acetate via liquid–liquid extraction. Bifendate was used as internal standard (IS). The current method was validated for linearity, intra-day and inter-day precisions, accuracy, extraction recovery, matrix effect and stability. The lower limits of quantification of ziyuglycoside I, 3β,19α-dihydroxyurs-12-en-28-oic-acid 28-β-d-glucopyranosyl ester, 3β-[(α-l-arabinopyranosyl) oxy]-urs-12,18(19)-dien-28-oic acid β-d-glucopyranosyl ester, rosamultin, 1β-hydroxyeuscaphic acid and alpinoside were 6.1, 4.9, 1.3, 3.8, 1.5 and 5.7 ng/mL, respectively. Intra-day and inter-day precision and the accuracy of the assay were in range from −9.48 to 12.74%. The extraction recoveries of analytes and bifendate (IS) from rat plasma ranged from 77.17% to 92.48%. Six compounds could be rapidly absorbed into blood (Tmax, 0.58–1.58 h), and then eliminated relatively slowly (t1/2, 6.86–11.63 h). The pharmacokinetic results might contribute to further guide the clinical application of S. officinalis.

Optimizing the front end test stand high performance H− ion source at RAL

2012 ◽  
Vol 83 (2) ◽  
pp. 02A701 ◽  
Author(s):  
D. Faircloth ◽  
S. Lawrie ◽  
C. Gabor ◽  
A. Letchford ◽  
M. Whitehead ◽  
...  
Keyword(s):  
High Performance ◽  
Ion Source ◽  
Test Stand ◽  
Front End

scholarly journals Anthocyanins Profile Characterization of Common Grape Hyacinth (Muscari neglectum Guss. ex Ten.) Flowers Growing in Hungary by High-performance Liquid Chromatography Coupled to Diode Array Detector and Mass Spectrometry using the Electrospray Ionization Interface

2020 ◽  
Vol 11 (01) ◽  
pp. 15-19
Author(s):  
Dmitry Olegovich Bokov ◽  
Eszter Riethmüller
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrospray Ionization ◽  
High Performance ◽  
Ion Source ◽  
Array Detector ◽  
Diode Array ◽  
Tandem Mass Spectrometric ◽  
Grape Hyacinth

Objective: Anthocyanins are one of the biologically active substances group playing an important role in the state of physiological functions referring to human health. This research aimed to investigate the anthocyanins profiles in the grape hyacinth (Muscari neglectum Guss. ex Ten.). Materials and methods: The identification of individual anthocyanins was carried using the method of high-performance liquid chromatography with diode array detection and mass spectrometry with electrospray ionization (DAD-ESI-MS) analysis. Chromatographic separation and tandem mass spectrometric analyses were performed on an Agilent 1100 HPLC system and Agilent 6410 triple quadrupole system equipped with an electrospray ion source (ESI) in positive ion mode. Results: In the M. neglectum flowers (tepals), nine individual anthocyanins, containing delphinidin, petunidin, malvidine, pelargonidin aglycones were found. In this research, we report anthocyanin profiles for the M. neglectum flowers for the first time. Conclusion: The obtained results concerning anthocyanins composition may be very useful for researchers in the field of the standardization and activity evaluation of extracts produced from M. neglectum.

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