Genes Related to Muscle Strength, Behavioral Trait, Pain Response, and Inflammation are Associated with Poor Outcome of the Total Joint Replacement Therapy in Primary Osteoarthritis Patients

OrthoMedia ◽  
2021 ◽  
Keyword(s):  
Muscle Strength ◽  
Replacement Therapy ◽  
Joint Replacement ◽  
Total Joint Replacement ◽  
Pain Response ◽  
Behavioral Trait ◽  
Poor Outcome ◽  
Primary Osteoarthritis

scholarly journals Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2422
Author(s):  
Chun-De Liao ◽  
Yen-Tzu Wu ◽  
Jau-Yih Tsauo ◽  
Pey-Rong Chen ◽  
Yu-Kang Tu ◽  
...  
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Exercise Training ◽  
Muscle Mass ◽  
Joint Replacement ◽  
Lower Limb ◽  
Functional Outcomes ◽  
Total Joint Replacement ◽  
Meta Analysis ◽  
Protein Supplementation

Aging and osteoarthritis (OA) are associated with a high risk of muscle mass loss, which can lead to physical disability. This study investigated the effectiveness of protein supplementation combined with exercise training (PS + ET) in improving muscle mass and functional outcomes in older adults with lower-limb OA. A comprehensive search of online databases was performed to identify randomized controlled trials (RCTs) on the effectiveness of PS + ET in older adults with hip or knee OA. Meta-analysis and risk of bias assessment of the included RCTs were conducted. Six RCTs were included in this systemic review; they had a median (range/total) Physiotherapy Evidence Database (PEDro) score of 7 (6–9) out of 10, respectively. Five RCTs that enrolled patients who underwent total joint replacement were included in this meta-analysis. The PS + ET group exhibited significant improvements in muscle mass (standard mean difference [SMD] = 1.13, p < 0.00001), pain (SMD = 1.36, p < 0.00001), and muscle strength (SMD = 0.44, p = 0.04). Our findings suggest that PS + ET improves muscle mass, muscle strength, and functional outcomes and reduces pain in older adults with lower-limb OA, particularly in those who have undergone total joint replacement.

Piroxicam spares buprenorphine after total joint replacement

1992 ◽  
Vol 63 (6) ◽  
pp. 658-660
Author(s):  
Michel Boeckstyns ◽  
Marianne Backer ◽  
Else Petersen ◽  
Iben Høj ◽  
Henrik Albrechtsen ◽  
...  
Keyword(s):  
Joint Replacement ◽  
Total Joint Replacement

Postoperative Anesthesia Of Elderly And Senile Patients With Total Joint Replacement Of The Lower Extremities

2020 ◽  
Vol 2 (09) ◽  
pp. 75-81
Author(s):  
Gaziev Z.T. ◽  
Avakov V.E. ◽  
Shorustamov M.T. ◽  
Bektemirova N.T.
Keyword(s):  
Epidural Analgesia ◽  
Postoperative Period ◽  
Joint Replacement ◽  
Total Joint Replacement ◽  
Lower Extremities ◽  
Multimodal Analgesia ◽  
Control Group ◽  
Patient Controlled Analgesia ◽  
Physical Status ◽  
Traumatic Injuries

Objective: To evaluate the efficacy and safety of patient-controlled analgesia through prolonged epidural analgesia after joint replacement of the lower extremities. Material and methods. We analyzed the postoperative period of 213 elderly and senile patients who were operated on for degenerative-dystrophic and traumatic injuries of the joints of the lower extremities. All patients underwent total joint replacement (164 - THA and 49 - TKA). The age of patients is from 65 to 90 years (average age was 78 ± 8 years) with a physical status of ASA 3 and above. All examined patients were divided into 2 groups. 63 patients comprised the main group, which in the postoperative period underwent patient-controlled analgesia (PCA) through prolonged epidural analgesia. The control group consisted of 150 patients, for the anesthesia of which in the postoperative period only standard systemic multimodal analgesia was used Conclusion. Patient-controlled analgesia is an alternative to traditional analgesic regimens. This method should be one of the main methods after surgical anesthesia for joint replacement of the lower limb in elderly and senile patients.

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