scholarly journals Prevalence of ABO, Rh and KELL Blood Group Types and Transfusion- Transmissible Infections (TTI) among Blood Donors in Najran City, Saudi Arabia

2021 ◽  
Vol 14 (02) ◽  
pp. 1065-1076
Author(s):  
Osama M Alshehri ◽  
Mohammed H Nahari ◽  
Elhashimi E Hassan ◽  
Musab F Alqahtani ◽  
Turki H Awaji
Keyword(s):  
Saudi Arabia ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Blood Group ◽  
Blood Donation ◽  
Complete Blood Count ◽  
Blood Groups ◽  
Type I ◽  
Blood Group Antigens ◽  
Safe Blood

The knowledge of Red blood cells polymorphism and blood group antigens prevalence at the local and regional levels is necessary for safe blood transfusion services. This study was aimed to estimate the prevalence of significant blood group phenotypes like ABO, Rh, and Kell among the Najran people of Saudi Arabia. The transfusion transmittable infection (TTI) rate and blood abnormalities among various blood types were assessed to ensure safe blood transfusion. ABO and Rh blood prevalence (n=970) and Rh phenotype polymorphism were estimated in over 531 unrelated donors. The blood samples were screened for certain TTIs like AHBC- Anti-hepatitis B core, HTLV-1- human T-lymphotropic virus type I, HCV- hepatitis C virus, HBsAg- Hepatitis B antigen, HIV- Human immunodeficiency virus, SIC- Sickle cell, MP- Malaria parasite, and SYP- Syphilis. The selected samples were also observed for blood abnormalities by performing a complete blood count (CBC). Out of 970 subjects, 966 were males, and only 4 were females. The O>A>B>AB blood groups were identified with 46.89, 29.3, 9.1, and 2.38% prevalence among Rh-positive phenotype. While in the Rh system, 87.6% and 12.3% of Rh positive and Rh negative was observed. Among 953 samples, the prevalence of seropositive donors was approximately 5.66%. The screening showed about 5.036, 0.104, 0.314, 0.209, 2.18, 0.104, and 0.209% positivity for AHBC, HCV, HBsAg, HIV, SIC, MP, and SYP respectively. Results found that the frequency of D, C, E, c, and e were 99.9%, 67.98, 25.8, 77.9, 98.49%, respectively, in over 531 subjects. The e allele was more prevalent in Najran city. After observing the variations in the CBC parameters among the donors, it was perceived that about 28.78, 99.9, 29.41, and 31.6% of blood abnormalities were noticed for O, AB, B, and A blood groups, respectively. For blood banks and transfusion services, which play a significant role in the medical care of the patient, awareness of the distribution of the blood group is essential. Increasing consistency of blood donation programs would improve both donor satisfaction and motivation for potential donations of blood in near future.

scholarly journals Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia

2019 ◽  
Vol 7 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Diana Mostafa ◽  
Essam I. Elkhatat ◽  
Pradeep Koppolu ◽  
Muna Mahgoub ◽  
Esam Dhaifullah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Blood Group ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group I

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.

scholarly journals PREVALENCE OF ABO AND RHESUS BLOOD GROUPS IN BLOOD DONORS. A STUDY FROM A TERTIARY CARE TEACHING HOSPITAL S.V.R.R.GOVT. GENERAL HOSPITAL IN RAYALASEEMA REGION OF ANDHRA PRADESH, TIRUPATI.

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Vijay Lakshmi ◽  
Dr. Durga Prasad Palla ◽  
Dr. D Surendra Babu ◽  
Dr. Chittooru Chandra Sekhar
Keyword(s):  
General Hospital ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Donation ◽  
Blood Groups ◽  
Blood Component ◽  
Blood Group Antigens ◽  
Age Group ◽  
Group Frequency ◽  
Agglutination Method

Back ground: The ABO and Rhesus –D blood group are the major blood group systems. The frequency of four main blood group systems varies in population throughout the world and even in different parts of the country. ABO & Rh blood group antigens play a Vital role in immunologic safety of whole blood and blood component transfusion and also useful in population genetic studies, in resolving medico legal issues. Aim: This study is aimed to document the frequency and distribution pattern of ABO and Rh among blood donors in S.V.R.R.Govt. General Hospital, Tirupati. Study Design: It is a retrospective record based study carried out at Model blood bank S.V.R.R.Govt. General Hospital Tirupati from January 2014 to December 2015. Material and Methods: The study was conducted on 13,040 donors. ABO and Rh typing was done by using slide agglutination method with antisera ABO and Rh (tulip Diag). Doubtful cases were confirmed by tube agglutination method and reverse grouping by using pooled A& B cells. The age group and sex of donors and frequency of ABO and Rh blood groups were reported in simple percentages. Results: In the present study the most common blood group was ‘O’ 5505 (42.2%) and least common being AB 778 (5.96%). The prevalence of Rh positive and negative distribution in the study population is 12267(94.07%) and 773(5.93%) respectively. Predominant donors belonged to age group between 18-35 years (85.37 %).Male donors (97.88%) are common than female donors (2.12%) with ratio. Blood group frequency with respect to ABO and Rh was found to be O>B>A>AB. Conclusion:   O positive blood group is significantly high  in our population  while AB Iis least.. Blood donation by females appears to be low provably because of illiteracy, malnutrition and social taboo. So female donor need to be motivated for blood donation.  Knowledge of frequencies of different blood groups is very important for blood banks and transfusion service polices for better use and good inventory of blood units. Key words: Blood groups ABO, Rh

scholarly journals IMPACT OF MULTIPLEX PCR IN REDUCING THE RISK OF RESIDUAL TRANSFUSION-TRANSMITTED HUMAN IMMUNODEFICIENCY AND HEPATITIS B AND C VIRUSES IN BURKINA FASO

2018 ◽  
Vol 10 (1) ◽  
pp. e2018041 ◽  
Author(s):  
Arzouma Paul YOODA ◽  
Serge Theophile SOUBEIGA ◽  
Kompingnin Yacouba NEBIE ◽  
Birama DIARRA ◽  
Salam SAWADOGO ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Hepatitis B ◽  
Burkina Faso ◽  
Multiplex Pcr ◽  
Blood Donation ◽  
Cross Sectional Study ◽  
Residual Risk ◽  
Serological Tests ◽  
Cross Sectional ◽  
The Impact

Background and ObjectiveThe improved performance of serological tests has significantly reduced the risk of human immunodeficiency and hepatitis B and C viruses transmission by blood transfusion, but there is a persistence of residual risk. The objective of this study was to evaluate the impact of multiplex PCR in reducing the risk of residual transmission of these viruses in seronegative blood donors in Burkina Faso.MethodsThis cross-sectional study was conducted from March to September 2017. The serological tests were performed on sera using ARCHITECTSR i1000 (Abbot diagnosis, USA). Detection of viral nucleic acids was performed by multiplex PCR on mini-pools of seronegative plasma for HBV, HCV and HIV using SaCycler-96 Real Time PCR v.7.3 (Sacace Biotechnologies). Multiplex PCR-positive samples from these mini-pools were then individually tested by the same method.Results A total of 989 donors aged 17 to 65 were included in the present study. "Repeat donors" accounted for 44.79% (443/989). Seroprevalences for HIV, HBV, and HCV were 2.53% (25/989), 7.28% (72/989) and 2.73% (27/989), respectively. Of the 14 co-infections detected, HBV/HCV was the most common with 0.71% (7/989) of cases. Of 808 donations tested by multiplex PCR, 4.70% (38/808) were positive for HBV while no donation was positive for HIV or HCV.Conclusion: Our study showed a high residual risk of HBV transmission through blood transfusion. Due to the high prevalence of blood-borne infections in Burkina Faso, we recommend the addition of multiplex PCR to serologic tests for optimal blood donation screening.

Prevalence of Duffy Blood Group Antigens and Phenotypes among Saudi Blood Donors in Southwestern Saudi Arabia

2021 ◽  
Vol 67 (01/2021) ◽  
Author(s):  
Amr Halawani ◽  
Muhammad Saboor ◽  
Hisham Abu-Tawil ◽  
Ayman Mahzari ◽  
Abdullah Mansor ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Group Antigens ◽  
Duffy Blood Group

scholarly journals Association of Viral Hepatitis with ABO Blood Group in apparently Normal Iraqi Blood Donors

2020 ◽  
Vol 10 (03) ◽  
pp. 421-425
Author(s):  
Suad Azeez Hassan ◽  
Suhair Hassan Alkutbi ◽  
Eman S. Nassir ◽  
Haider Hassan Lilo
Keyword(s):  
Hepatitis B ◽  
Blood Group ◽  
Blood Donors ◽  
Blood Groups ◽  
Public Health Issue ◽  
Blood Group A ◽  
B Virus ◽  
Group A ◽  
Group B ◽  
Apparently Healthy

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are counted as a public health issue worldwide. The virus is transmitted to infect others through blood and blood products. Appointed blood groups and Rh-positive are more prone to the transmission of the infection by blood transfusion. The aim of this study is to find out the frequency of hepatitis B and C in apparently healthy blood donors and whether there is an association between ABO and Rh blood groups. ABO blood groups and their relationship with HBV and HCV infections were studied in 87,124 blood donors of both genders. Out of these donors, 353 individuals were found to be infected with HBV and HCV with a ratio of 1:250. The study was conducted between January to June 2018, which was presented to the Central Blood Bank in Baghdad and Al-Razi Medical Centre. It found that most hepatitis B and C blood donors were blood group O with a prevalence of 33.7 and 45.5%, respectively, while the results for those with blood group A showed 28.5 and 22.7% HBV and HCV infections, respectively. On the other hand, the incidence of HBV in individuals with blood group B was 29.8%, and HCV was 23.8%. AB blood group donors demonstrated the least incidence at 7.9% for both HBV and HCV. In conclusion, it has been found that there is a significant association between blood groups and Rh factor with hepatitis B and C infections.

scholarly journals Distribution and Association of ABO and Rh Blood Group Antigens with BMI Among Nepalese and Indian Students Studied in a Medical College of Nepal

2021 ◽  
Vol 17 (3) ◽  
pp. 265-278
Author(s):  
Kalipada Kar ◽  
Sujata Kar
Keyword(s):  
Body Mass Index ◽  
Medical Students ◽  
Blood Group ◽  
Body Mass ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Medical College ◽  
Indian Origin ◽  
Overweight Group ◽  
The Difference

Introduction: Blood group antigens and body mass index of human are gaining importance for many diseases. Some attempts were reported to find any relationship between BMI and Blood groups with some contradictions. The possible association between BMI and blood groups of Nepalese and Indian medical students is yet to be established. Methods: Blood groups, ABO and Rh systems and body mass index (BMI) of participants, medical students of Nepalese and Indian origin were determined and analyzed statistically. Results: The distribution frequencies of 10.56%, 17.08%, 3.06%, and 20.28% females and 9.03%, 16.39%, 3.61% and 20.0% males of both the countries were present in A, B, AB and O blood groups, respectively. Rh-negative participants were predominantly present in O blood group. The observed frequencies of participants with different BMI group were distributed as 56.11%, 24.72%, 10.69% and 8.47% in Normal, Overweight, Underweight and Obese groups, respectively. Underweight participants were prevalent in O group and in females. The difference between the distribution of Nepalese females and males with Normal BMI was found significant in A and O. A distribution pattern of B>O>A>AB was observed for Overweight group. The occurrence of Obese is few folds higher among Indian participants than Nepalese and prevalent in males. Obese participants were found more associated with B and O blood group. Conclusions: Participants with A were more prevalent among Nepalese in respect to Indian. Rh-negative participants were distributed as 1.67% and 5.0% in Nepalese and Indians, respectively and predominantly present in O (4.44%) and are more prevalent in Indian males. In Normal BMI Nepalese were significantly more as compared to Indians. In the Underweight group females were significantly more prevalent as compared to males and found maximally associated with O blood group and most of them are Nepalese. In Overweight group males were more than females. Participants with obesity were mostly present in B and O blood group and most of them are Indian.

scholarly journals Frequency of ABO-Rhesus Blood Groups in the Western Region of Saudi Arabia

2018 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
Faisal M. Alzahrani ◽  
Saeed S. Shaikh ◽  
Muzaheed A. Rasheed
Keyword(s):  
Social Sciences ◽  
Saudi Arabia ◽  
Blood Group ◽  
Blood Groups ◽  
Western Region ◽  
Western Area ◽  
Group A ◽  
The Western Region ◽  
Abo Blood Grouping ◽  
Blood Grouping

The western region of Saudi Arabia is known as a multinational region with different ethnic groups of people. This study aims to evaluate the ABO and rhesus blood groups among study subjects in the Western area of Saudi Arabia and their comparison with other regions of the Kingdom. It is a retrospective study. 35,388 participants were included. ABO blood grouping was done using tube method. Agglutination in any tube or hemolysis was considered as positive. Blood grouping was done by a preliminary finger prick, and was repeated again and a serum sample was obtained at the time of donation. Statistical Package for Social Sciences software was used for the data analysis. Results showed that the most common blood group is O, (50.1%) followed by A (29.7%), B (16%) and less frequent is AB (4.1%). Rhesus positive were 91.3%, while rhesus negative were 8.63%. These results demonstrate that the most common blood group in the Western province is O. Blood group A was noticed to be less frequent. Understanding the frequencies of the blood groups and their phenotypes is crucial for blood banking and for setting transfusion service protocols.  

scholarly journals Safe Blood Transfusion and Ethical Issues in Transfusion Medicine

1970 ◽  
Vol 19 (2) ◽  
pp. 144-149
Author(s):  
ASM Nurunnabi ◽  
M Jahan ◽  
MA Alam ◽  
MM Hoque
Keyword(s):  
Blood Transfusion ◽  
Best Practices ◽  
Ethical Issues ◽  
Blood Donation ◽  
Analytical Framework ◽  
Transfusion Medicine ◽  
Blood Components ◽  
Blood Management ◽  
Specialist Physician ◽  
Safe Blood

Transfusion of blood and blood components, as a specialized modality of patient management, saves millions of lives worldwide. Transfusion Medicine is an integral and indispensable part of the healthcare system now. This topic that has been selected is intended to assist the transfusion physician or other specialist physician in acquiring the sense of responsibility for transfusion services. The section includes best practices in handling and administering blood for transfusion, blood management, risks (infectious and non-infectious diseases) of blood components. This topic has been intended to serve in a manner that this little supplement on the state-of-the-practice will facilitate safe patient transfusions, when transfusions are indicated, or minimize or avoid transfusions as appropriate in institutions of all sizes. The 'four principles' approach - autonomy, beneficence, non-maleficence, and justice - offers a common, basic moral analytical framework and a common, basic moral language to think about ethical issues in any field of health care services.Key words: Transfusion medicine; blood transfusion services; safe blood transfusion; voluntary blood donation; ethical issues. DOI: 10.3329/jdmc.v19i2.7087J Dhaka Med Coll. 2010; 19(2) : 144-149

scholarly journals Association of ABO and Rh Blood Group Phenotypes with Type 2 Diabetes Mellitus at Felege Hiwot Comprehensive Referral Hospital Bahir Dar, Northwest Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Biruk Legese ◽  
Molla Abebe ◽  
Alebachew Fasil
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Group ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Chi Square ◽  
Group B ◽  
Rh Blood Group

Background. ABO and Rh blood group antigens are thought to be among genetic determinants of type 2 diabetes mellitus. Identification of blood group phenotypes are more associated with type 2 diabetes mellitus. It will be helpful for individuals who are susceptible blood groups to take care of themselves by avoiding other predisposing factors and taking preventive measures. Methods. Hospital-based comparative cross-sectional study was carried out from February to April 2019 at Felege Hiwot Comprehensive Referral Hospital. Sociodemographic and clinical data were collected with a semistructured pretested questionnaire. ABO and Rh Blood group were determined by slide and test tube methods. Biochemical parameters were determined with Mindray BS-200E fully automated clinical chemistry analyzer. Data were analyzed by IBM SPSS version 20 statistical software. Chi-square test and logistic regression analysis were employed for data analysis. A P value of < 0.05 was considered statistically significant. Results. From a total of 424 participants included for this study, blood group O was found higher in frequency with 74 (34.9%) and 97 (45.75%) for cases and healthy controls, respectively. ABO blood groups showed significant association with T2DM, a chi-square value of 12.163 and P value of 0.007. However, the Rh blood group was not associated with T2DM. Binary logistic regression analysis revealed that blood group B had a higher risk (OR: 2.12, 95% CI: 1.33-3.32) and blood group O had decreased risk (OR: 0.636, 95% CI: 0.43-0.94) of T2DM as compared to other blood groups. Conclusion. ABO blood group antigens showed significant association with type 2 diabetes mellitus. Blood group B was associated with an increased risk and O blood group with decreased risk of type 2 diabetes mellitus.

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