scholarly journals Exploration of Antifungal Potential of Azadirachta Indica against Microsporum Gypseum

2020 ◽  
Vol 13 (02) ◽  
pp. 921-925
Author(s):  
Puneet Sudan ◽  
Manish Goswami ◽  
Jitender Singh
2018 ◽  
Vol 11 (4) ◽  
pp. 2175-2179
Author(s):  
Puneet Sudan ◽  
Jitender Singh

The aqueous extracts of Azadirachta indica, Trigonella foenum graecum, Allium sativum, Cinnamomum tamala, Capsicum annum were used to test their antifungal properties against the keratinophilic fungus Microsporum gypseum. Plant aqueous extracts were taken at two different concentrations of 5% and 10%. The present study revealed that Allium sativum and Capsicum annum at 10% conc. had more potent antifungal potential as compared to all the other extracts followed by Azadirachta indica, Trigonella foenum graecum and Cinnamomum tamala.


2020 ◽  
Vol 11 (1) ◽  
pp. 646-649 ◽  
Author(s):  
Puneet Sudan ◽  
Manish Goswami ◽  
Jitender Singh

Trigonella foenum-graecum (fabaceae) is commonly used as condiments and spices in Indian and Asian food to flavour, colour, and texture of food, and it is employed in various medicinal purposes in traditional systems. The biological activity of fenugreek can be easily accessed from previous research conducted by several researchers. The present research was conducted to find out the antifungal potential of various extracts of dried powder of fenugreek seeds by means of paper disc diffusion method, with petroleum ether, ethyl acetate, ethanol, and aqueous solvents in 25 μml, 50 μml and 100 μml concentrations against Microsporum gypseum. Clotrimazole was used as a standard. The present study revealed that fenugreek is a potent antifungal agent against Microsporum gypseum. The ethanol extract of fenugreek using 100 μml concentrations depicted the highest zone of inhibition of 16.510+ 0.85mm and 38.395% of mycelial inhibition against a tested pathogen. While drug extracts in other solvents also revealed reasonable to least antifungal potential. This finding tells us that fenugreek extracts tested proved to be a potent antifungal agent against Microsporum gypseum. It was found that ethanol extract of fenugreek is best effective against tested strain. This exploration of fenugreek extracts has confirmed its importance, particularly in the area of influence on dermatophytic fungal strain.


2018 ◽  
Author(s):  
Vaishali A Fulzele Asifa Qureshi and AA Fulzele Vaishali A Fulzele Asifa Qureshi and AA Fulzele ◽  

2018 ◽  
Author(s):  
Vaishali A. Fulzele Asifa Qureshi and A.A. Fulzele Vaishali A. Fulzele Asifa Qureshi and A.A. Fulzele ◽  

2020 ◽  
Vol 11 (2) ◽  
pp. 1612-1616
Author(s):  
Puneet Sudan ◽  
Manish Goswami ◽  
Jitender Singh

Ginger (Zingiber officinale) has been utilized since ancient times in various traditional systems of medicine like Ayurveda, Unani, and naturopathy because of antifungal and antimicrobial potential against diverse fungal and microbial infections.  Moreover,  in the Asian subcontinent like  India, Pakistan, Bangladesh, etc., ginger is used in many food preparations as a condiment and boiled decoction to treat cold-cough and indigestion. The present research was conducted to find out the antifungal potential of various extracts of dried ginger powder, by means of paper disc diffusion method, with petroleum ether, ethyl acetate, ethanol and aqueous solvents in 25 μml,50 μml and 100 μml concentrations against Microsporum gypseum. Clotrimazole was used as a standard. The present study revealed that ginger is a potent antifungal agent against Microsporum gypseum. The ethanol extract of ginger using 100 μml concentrations depicted the highest zone of inhibition of 19.840+ 0.65mm and 46.139% of mycelial inhibition against the tested pathogen. While other drug extracts in different solvents also revealed reasonable to least antifungal potential. This finding tells us that ginger extracts tested proved to be a potent antifungal agent against Microsporum gypseum.It was found that ethanol extract of ginger is best effective against tested strain. This exploration of ginger extracts has confirmed its importance, particularly in the area of influence on dermatophytic fungal strain.


2020 ◽  
Vol 11 (1) ◽  
pp. 63-65
Author(s):  
Puneet Sudan ◽  
Manish Goswami ◽  
Jitender Singh

Plant-derived antifungal agents will always remain as area of interest for researchers to overcome the issues pertaining to resistance and harmful adverse effects associated with synthetic drugs. Cynodon dactylon is a well known plant which grows wildly and used for the treatment of many diseases like wounds, warts, cramps, measles and also tumors. This research was done as, till date no scientific evidence was accessible concerning the antifungal potential of the hydroalcholic extract of the whole plant. In the present work, antifungal potential of hydroalcholic extract of Cynodon dactylon was evaluated against Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum. The antifungal potential was evaluated by means of the agar well diffusion method. The diameter of the clear inhibition zone around the well was measured. The hydroalcholic extract of Cynodon dactylon had promising antifungal potential against all the tested fungal strains. Finally, it can be concluded from the calculated findings that hydroalcholic extract of the whole plant of Cynodon dactylon may be considered as a promising antifungal herbal plant and can be exploited as a great herbal resistance free source for treatment of various fungal infections.


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