scholarly journals Antifungal Potential of Aqueous Extract of Some Traditional Plants on Microsporum Gypseum

2018 ◽  
Vol 11 (4) ◽  
pp. 2175-2179
Author(s):  
Puneet Sudan ◽  
Jitender Singh
Keyword(s):  
Azadirachta Indica ◽  
Allium Sativum ◽  
The Other ◽  
Keratinophilic Fungus ◽  
Microsporum Gypseum ◽  
Aqueous Extracts ◽  
Trigonella Foenum Graecum ◽  
Capsicum Annum ◽  
Cinnamomum Tamala ◽  
Antifungal Potential

The aqueous extracts of Azadirachta indica, Trigonella foenum graecum, Allium sativum, Cinnamomum tamala, Capsicum annum were used to test their antifungal properties against the keratinophilic fungus Microsporum gypseum. Plant aqueous extracts were taken at two different concentrations of 5% and 10%. The present study revealed that Allium sativum and Capsicum annum at 10% conc. had more potent antifungal potential as compared to all the other extracts followed by Azadirachta indica, Trigonella foenum graecum and Cinnamomum tamala.

scholarly journals Antifungal potential of Fenugreek Seeds (Trigonella foenum-graecum) Crude Extracts against Microsporum gypseum

2020 ◽  
Vol 11 (1) ◽  
pp. 646-649 ◽  
Author(s):  
Puneet Sudan ◽  
Manish Goswami ◽  
Jitender Singh
Keyword(s):  
Antifungal Agent ◽  
Ethanol Extract ◽  
Diffusion Method ◽  
Microsporum Gypseum ◽  
Zone Of Inhibition ◽  
Fenugreek Seeds ◽  
Trigonella Foenum Graecum ◽  
Antifungal Potential ◽  
Area Of Influence ◽  
Paper Disc

Trigonella foenum-graecum (fabaceae) is commonly used as condiments and spices in Indian and Asian food to flavour, colour, and texture of food, and it is employed in various medicinal purposes in traditional systems. The biological activity of fenugreek can be easily accessed from previous research conducted by several researchers. The present research was conducted to find out the antifungal potential of various extracts of dried powder of fenugreek seeds by means of paper disc diffusion method, with petroleum ether, ethyl acetate, ethanol, and aqueous solvents in 25 μml, 50 μml and 100 μml concentrations against Microsporum gypseum. Clotrimazole was used as a standard. The present study revealed that fenugreek is a potent antifungal agent against Microsporum gypseum. The ethanol extract of fenugreek using 100 μml concentrations depicted the highest zone of inhibition of 16.510+ 0.85mm and 38.395% of mycelial inhibition against a tested pathogen. While drug extracts in other solvents also revealed reasonable to least antifungal potential. This finding tells us that fenugreek extracts tested proved to be a potent antifungal agent against Microsporum gypseum. It was found that ethanol extract of fenugreek is best effective against tested strain. This exploration of fenugreek extracts has confirmed its importance, particularly in the area of influence on dermatophytic fungal strain.

scholarly journals Exploration of Antifungal Potential of Azadirachta Indica against Microsporum Gypseum

2020 ◽  
Vol 13 (02) ◽  
pp. 921-925
Author(s):  
Puneet Sudan ◽  
Manish Goswami ◽  
Jitender Singh
Keyword(s):  
Azadirachta Indica ◽  
Microsporum Gypseum ◽  
Antifungal Potential

scholarly journals Effect Of Garlic (Allium Sativum) And Fenugreek (Trigonella Foenum-Graecum) Extracts On Aspergillus Fumigatus

2005 ◽  
Vol 29 (1) ◽  
pp. 137-151
Author(s):  
Ali A. S. AI-Mayah
Keyword(s):  
Aspergillus Fumigatus ◽  
Allium Sativum ◽  
Agar Plate ◽  
Garlic Extract ◽  
Poultry Feed ◽  
Aqueous Extracts ◽  
Test Fungus ◽  
Trigonella Foenum Graecum ◽  
Feed Samples ◽  
Ofaspergillus Fumigatus

The effect of garlic (Allium Sativum) & fenugreek (Trigonellafoenum-graecum) aqueous extracts (GE & FE) were studied with respect to theirantifungal activity against Aspergillus fumigatus. Garlic extract (GE) at 5% wascompletely inhibit the growth of the test fungus in the agar plate methodwhether the extract mixed with or spreaded on the surface of the medium.Fenugreek extract (FE) at 10% did not exhibit any effect against this fungus inthe sane method. Garlic extract (GE) & garlic chips (GC) inhibited the growth ofAspergillus fumigatus inoculated in poultry feed samples. The viable sporecount per gram of feed treated with garlic was less than control feed samples.Garlic extract (GE) was more effective than garlic chips (GC). Fenugreekextract (FE) at 10% (did not inhibit the growth of the same fungus and the viablespore count was the same as the control.

Phytochemical Constituents of Tulbaghia violacea Harv Extract and its Antifungal Potential Against Cryptococcus neoformans and Cryptococcus gattii

2019 ◽  
Vol 9 (4) ◽  
pp. 330-340
Author(s):  
Mitradev Pattoo ◽  
Vuyokazi Belewa ◽  
Benesh Munilal Somai
Keyword(s):  
Antifungal Activity ◽  
Cryptococcus Neoformans ◽  
Antifungal Therapy ◽  
Developing World ◽  
Chemical Constituents ◽  
Cryptococcus Gattii ◽  
Plant Part ◽  
Aqueous Extracts ◽  
Antifungal Activities ◽  
Antifungal Potential

Background:In both the developed and developing world, the mortality rates of people afflicted with cryptococcosis are unacceptably high despite the availability of antifungal therapy. The disease is caused by Cryptococcus neoformans (predominantly in immunocompromised individuals) and by Cryptococcus gattii. Globally the disease is estimated to cause around 600,000 deaths annually. Antifungal therapy is available, but in the developing world, may be unaffordable to many people, there is an increasing threat of resistance to the available drugs and our repertoire of antifungal drugs is very limited. Consequently, more research has been focusing on the use of medicinal plants as therapeutic agents. The originality of the current study is that although Tulbaghia violacea is a well-documented medicinal plant, the chemical composition of aqueous extracts and their antifungal potential against pathogenic yeasts are unknown. This is the first study that evaluates the chemical constituents of aqueous T. violacea root, leaf, rhizome and tuber extracts and their corresponding antifungal activities against C. neoformans and C. gattii.Objectives:The study aimed to investigate the phytochemical composition and antifungal potential of Tulbaghia violacea root, leaf, rhizome and tuber extracts against Cryptococcus neoformans and Cryptococcus gattii.Methods:Roots, leaves, rhizomes and tubers were extracted with water only for 48 h at room temperature with continuous shaking. Extracts were filter sterilized, freeze-dried and, chemically analyzed for saponin, flavonol, phenolic and tannin content. Chemical constituents of each extract were also identified by GC-MS analysis. The Minimum Inhibitory Concentration (MIC) of suitably diluted extracts of each plant part were also performed against C. neoformans and C. gattii, yeast pathogens commonly associated with HIV/AIDS sufferers.Results:Phytochemical analysis showed different concentrations of saponins (between 1023 and 2896.73 µg/ml), phenolics (between 16.48 and 51.58 µg/ml) and tannins (between 122.30 and 543.07 µg/ml) present in the different extracts. No flavonols were detected. GC-MS analysis identified a complex mixture of phytochemicals composed predominantly of sulphide, pyran, furan and ketone containing compounds to be present in the different plant parts. All extracts were dominated by the presence of 4 H-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl, a pyran known to have antifungal properties. Although the root, leaf, rhizome and tuber extracts exhibited antifungal activities against both fungi, the rhizome and tuber extract were found to possess the lowest MIC’s of 1.25 mg/ml and 2.5 mg/ml against Cryptococcus neoformans and Cryptococcus gattii respectively.Conclusion:T. violacea extracts have a complex constituent of phytochemicals and each plant part exhibited a strong antifungal activity against C. neoformans and C. gattii. The rhizome and tuber extracts showed the highest antifungal activity against C. neoformans and C. gattii respectively. Thus, T. violacea aqueous extracts are strong candidates for further development into an antifungal chemotherapeutic agent.

scholarly journals Prospects of botanical pesticides in management of Iroko gall bug, Phytolyma fusca (Hemiptera, Psylloidea) under laboratory and field conditions

2021 ◽  
Vol 82 (1) ◽  
Author(s):  
Juliana Amaka Ugwu
Keyword(s):  
West Africa ◽  
Azadirachta Indica ◽  
Residual Effects ◽  
Aqueous Extracts ◽  
Plant Materials ◽  
Piper Guineense ◽  
Early Management ◽  
Ethanol Extracts ◽  
Milicia Excelsa ◽  
Contact Effects

Abstract Background Iroko gall bug, Phytolyma fusca Walker, is a major insect pest of Milicia excelsa (Iroko) seedling hampering its propagation in West Africa. Milicia excelsa is an indigenous forest timber tree in the tropical rain forest of West Africa with a very high value in international trade due to its wood quality. Sustainable management of P. fusca infestations on Iroko seedlings have not been achieved due to their cryptic nature and multivoltine generations. This study evaluated the residual and contact effects of crude ethanol and aqueous extracts of four plants (Azadirachta indica, Jatropha curcas, Piper guineense, and Aframomum melegueta) on adult P. fusca in the laboratory and field. Results All the extracts had residual effects and contact effects on adult insects in the laboratory at 75% and 100% concentrations of applications. Azadirachta indica, P. guineense, and A. melegueta gave 80–100% adult mortality at both concentrations in the laboratory; their efficacies were comparable to cypermethrin. The ethanol extracts of P. guineense and A. indica were more effective than other extracts in protecting the seedlings against Phytolyma infestations in the field. They significantly (p < 0.01) reduced infestation compared to other extracts and control. Ethanol extracts of the tested plant materials were more effective than their aqueous extracts both in the laboratory and field. Conclusion The results proved that P. guineense and A. indica extracts were very potent and promising in protecting Milicia excelsa seedlings against Phytolyma fusca infestations and they can be used in the early management of Phytolyma infestations in the field.

scholarly journals ANTIFUNGAL POTENTIAL OF ETHANOL EXTRACTS OF ALLIUM SATIVUM AND ALLIUM AMPELOPRASUM

2017 ◽  
Vol 10 (4) ◽  
pp. 207
Author(s):  
Shahid Khan ◽  
Neeta Raj Sharma
Keyword(s):  
Growth Inhibition ◽  
Causative Agent ◽  
Magnaporthe Oryzae ◽  
Allium Sativum ◽  
Microtiter Plate ◽  
Blast Disease ◽  
Allium Ampeloprasum ◽  
Antifungal Potential ◽  
Ethanol Extracts

Objective: In vitro analysis of Allium sativum and Allium ampeloprasum was performed to evaluate their antifungal potential against Alternaria triticina (ITCC 5496), causative agent of leaf blight in wheat and Magnaporthe oryzae (ITCC 6808), causative agent of blast disease in rice.Methods: Ethanol extracts of A. ampeloprasum and A. sativum were prepared by crushing their bulb in liquid nitrogen and then immersing them in 90% ethanol and 100% ethanol separately. The antifungal activity test was determined by quantitative assay using 96-well microtiter plate and results were statistically analyzed using GraphPad Prism v. 5.03.Results: A. triticina and M. oryzae showed above 90% and 95% growth inhibition, respectively against the ethanol extracts of A. ampeloprasum. Conversely, growth inhibition of either fungus remained mostly below 35% against ethanol extracts of A. sativum at all tested concentrations.Conclusion: Ethanol extracts of A. ampeloprasum have relatively higher antifungal potential than ethanol extracts of A. sativum and could be considered as a natural alternative to chemical fungicides.Keywords: Allium sativum, Allium ampeloprasum, Alternaria triticina, Magnaporthe oryzae.

scholarly journals Phytochemical screening and evaluation of antioxidant capacities of Allium cepa, Allium sativum, and Monodora myristica using in vitro and in vivo models

2021 ◽  
Vol 1 (1) ◽  
pp. 41-52
Author(s):  
Chioma E. Irozuru Irozuru ◽  
Janet O. Olugbodi ◽  
Uche Okuu Arunsi ◽  
Olusola Ladeji
Keyword(s):  
Ascorbic Acid ◽  
Allium Cepa ◽  
Plant Extracts ◽  
Allium Sativum ◽  
Reducing Power ◽  
Aqueous Extracts ◽  
In Vivo Models ◽  
Monodora Myristica

Background: Allium cepa, Allium sativum, and Monodora myristica are commonly sourced food condiments in every household in Nigeria. In the present study, we investigated the phytochemical compositions, in vitro and in vivo antioxidant activity of these plants. Methods: The aqueous extracts from the A. cepa, A. sativum, and M. myristica were evaluated for phytochemical composition using standard protocols while the antioxidant activities were evaluated using the reducing power assay. Forty-five (45) Male Wistar rats (weighing 185±10 g) were divided into five groups (n=9) and were orally administered with 100 mg/kg BW each of A. sativum, M. myristica, A. cepa, and ascorbic acid while the control group received 0.5 mL/kg BW distilled water alone. Animals (n=3) from each group were sacrificed after the 20th, 25th, and 30th days of oral administration. The blood and tissue samples were collected for the analysis of biochemical parameters. Result: Our results revealed the presence of flavonoids, alkaloids, tannins, saponins, and terpenes in the plant extracts. A. sativum had the highest reducing power capacity followed by M. myristica and then A. cepa. The in vitro antioxidants activities demonstrated by the plant extracts were higher than that of ascorbic acid but less than butylated hydroxytoluene. In vivo antioxidant studies showed a marked increase (p<0.05) in the level of catalase with a concurrent decrease (p<0.05) in the levels of MDA and H2O2 in the liver and kidney of rats administered with aqueous extracts of the condiments compared to the normal control and ascorbic acid in the following order control < ascorbic acid < A. cepa < M. myristica < A. sativum. Conclusion: Based on these findings, we infer that the aqueous extracts of A. cepa, A. sativum, and M. myristica are rich in antioxidants and as a result could serve as promising novel functional foods and nutraceuticals

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