scholarly journals Efficacy of Chlorhexidine Varnish in Patients Undergoing Multibracket Fixed Orthodontic Treatment: A Controlled Clinical Study

2018 ◽  
Vol 11 (2) ◽  
pp. 945-950 ◽  
Author(s):  
Arjun Sehgal ◽  
Siddarth Shetty ◽  
Ashith M. V ◽  
Nidhin Philip Jose ◽  
Utkarsh Mangal

During fixed orthodontic treatment, maintenance of a good gingival health is challenging. This necessitates use of prophylactic measures, such as use of fluoridated tooth pastes and application of varnish. Use of chlorhexidine (CHX) varnish, is believed to reduce the bacterial count and have a longer duration of action, by virtue of sustained release. Therefore, the aim of the present study is to assess the clinical effects of chlorhexidine varnish (Cervitec plus) on plaque accumulation and gingival health during multibracketorthodontic treatment.

Author(s):  
Thejaswi R. Thupakula ◽  
Bela Makhija ◽  
Arpana Haritwal

vBackground: Induction of labour is the intentional initiation of labour before spontaneous onset for the purpose of delivery of fetoplacental unit. Failure of induction is responsible for increased incidence of caesarean delivery. This study performed to assess and compare the clinical effects of sustained release vaginal insert versus intracervical gel in primiparous women with term pregnancy in terms of improvement of Bishop’s score, Induction delivery interval, incidence of hyperstimulation, maternal and neonatal outcomes.Methods: A total 100 consecutive term pregnant women who underwent labor induction for fetal or maternal indications were divided randomly into two groups. Group A - sustained release Vaginal insert and Group B - Intracervical gel. Informed consent was taken from each patient.Results: Statistically significant increase in final Bishop’s score (p=0.008) and hyperstimulation (p=0.04) was seen in Vaginal insert group as compared to Intracervical gel group, while there were no statistically significant differences in maternal outcomes, neonatal outcomes and need for oxytocin augmentation in both groups.Conclusions: In this study we found that insert did not improve the induction delivery interval or rate of successful induction, nor did it have any advantage in terms of neonatal outcome although it did improve the Bishops score – Its advantage was in terms of single application, few prevaginal examinations, longer duration of action and immediate retrieval in case of hyperstimulation. Its main drawback remained the maintenance of cold chain without which its efficacy decreases. Another significant observation was the dropout rate of insert (16%).


1979 ◽  
Vol 7 (6) ◽  
pp. 556-559 ◽  
Author(s):  
G A A Oyemade ◽  
B O Onadeko

Forty-six patients (seventeen male, twenty-nine female) with musculoskeletal disease were put on a controlled clinical study comparing sulindac with ibuprofen and soluble aspirin. Twenty patients were treated with sulindac 200 mg twice daily, twelve received sulindac 100 mg twice daily, eight had ibuprofen 400 mg thrice daily and six treated with soluble aspirin 600 mg thrice daily. All patients did well on these drugs, but the ones on sulindac 200 mg twice daily showed better response than sulindac 100 mg twice daily. It proved to have the same efficacy as ibuprofen and soluble aspirin; but had less side-effects and also patients required to take the drug only twice daily to get relief because of its prolonged duration of action.


2015 ◽  
Vol 45 ◽  
pp. 1421-1428 ◽  
Author(s):  
Bayram ÇÖREKÇİ ◽  
Ebubekir TOY ◽  
Fırat ÖZTÜRK ◽  
Sıddık MALKOÇ ◽  
Bora ÖZTÜRK

1951 ◽  
Vol 17 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Frank C. Bone ◽  
Chester Cassel ◽  
Julian M. Ruffin ◽  
Robert J. Reeves

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