Nadolol eye drops in glaucoma and ocular hypertension: A controlled clinical study of dose response and duration of action

1981 ◽  
Vol 217 (4) ◽  
pp. 309-314 ◽  
Author(s):  
G. K. Krieglstein
1979 ◽  
Vol 7 (6) ◽  
pp. 556-559 ◽  
Author(s):  
G A A Oyemade ◽  
B O Onadeko

Forty-six patients (seventeen male, twenty-nine female) with musculoskeletal disease were put on a controlled clinical study comparing sulindac with ibuprofen and soluble aspirin. Twenty patients were treated with sulindac 200 mg twice daily, twelve received sulindac 100 mg twice daily, eight had ibuprofen 400 mg thrice daily and six treated with soluble aspirin 600 mg thrice daily. All patients did well on these drugs, but the ones on sulindac 200 mg twice daily showed better response than sulindac 100 mg twice daily. It proved to have the same efficacy as ibuprofen and soluble aspirin; but had less side-effects and also patients required to take the drug only twice daily to get relief because of its prolonged duration of action.


2019 ◽  
Vol 186 (9) ◽  
pp. 283-283
Author(s):  
Minna Suokko ◽  
Lasse Saloranta ◽  
Terttu Lamminen ◽  
Tarmo Laine ◽  
Jonathan Elliott

There is a need for an effective and safe emetic agent that dog owners could easily administer to their dogs following veterinary advice in cases of potential poisoning. As a response to this need, a randomised, double-blind, multi-site, clinical field study was performed to assess the efficacy, safety and usability of ropinirole eye drops to induce vomiting in dogs. Ropinirole (target dose 3.75 mg/m2) was applied to eyes of 100 dogs, and 32 dogs received placebo. The drug was administered by the dog owner at a veterinary clinic under the supervision of a veterinarian and led to vomition in 95% of the ropinirole-treated dogs within 30 min. The median time to first vomit was 10 min (range: 3–37 min). None of the dogs receiving placebo vomited in this time period. All owners were able to administer the product and 96% of them assessed the administration to be very easy or easy, which was confirmed by the observing veterinarian. Some ocular signs were seen both with ropinirole and placebo, hyperaemia being the most common. All observed signs were transient and in most cases mild. Ropinirole eye drops provided an effective, safe and reliable means to induce emesis in dogs.


2018 ◽  
Vol 11 (2) ◽  
pp. 945-950 ◽  
Author(s):  
Arjun Sehgal ◽  
Siddarth Shetty ◽  
Ashith M. V ◽  
Nidhin Philip Jose ◽  
Utkarsh Mangal

During fixed orthodontic treatment, maintenance of a good gingival health is challenging. This necessitates use of prophylactic measures, such as use of fluoridated tooth pastes and application of varnish. Use of chlorhexidine (CHX) varnish, is believed to reduce the bacterial count and have a longer duration of action, by virtue of sustained release. Therefore, the aim of the present study is to assess the clinical effects of chlorhexidine varnish (Cervitec plus) on plaque accumulation and gingival health during multibracketorthodontic treatment.


2015 ◽  
Vol 32 (12) ◽  
pp. 1263-1279 ◽  
Author(s):  
Vladimir V. Brzheskiy ◽  
Elena L. Efimova ◽  
Tatiana N. Vorontsova ◽  
Vladimir N. Alekseev ◽  
Olga G. Gusarevich ◽  
...  

1951 ◽  
Vol 17 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Frank C. Bone ◽  
Chester Cassel ◽  
Julian M. Ruffin ◽  
Robert J. Reeves

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