scholarly journals Recent Trends in Biomedical Applications of Nanomaterials

2018 ◽  
Vol 15 (2) ◽  
pp. 235-243 ◽  
Author(s):  
Khalid E. Ibrahim ◽  
Amel O. Bakhiet ◽  
Ayaat Khan ◽  
Haseeb A. Khan
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Disease Diagnosis ◽  
Diagnosis And Treatment ◽  
Biomedical Sciences ◽  
Design And Synthesis ◽  
Recent Trends ◽  
Targeted Drug ◽  
New Generation

In recent years, there have been enormous developments in utilizing the potential of nanotechnology in different fields including biomedical sciences. The most remarkable biomedical applications of nanoparticles (NPs) are in the diagnosis and treatment of various diseases. Functionalization of NPs renders them unique properties so that they can be used as contrast agent for dual or triple modal imaging. The design and synthesis of new generation NPs aiming at targeted drug delivery has revolutionized the safe and effective therapies for complex and difficult to treat diseases. The theranostic NPs possess the dual capabilities for disease diagnosis and treatment. This review highlights the biomedical applications of NPs based on recent reports published in this area of research.

Design and synthesis of novel amphiphilic Janus dendrimers for bone-targeted drug delivery

Tetrahedron ◽  
2012 ◽  
Vol 68 (14) ◽  
pp. 2943-2949 ◽  
Author(s):  
Junzhu Pan ◽  
Min Wen ◽  
Dongqin Yin ◽  
Bo Jiang ◽  
Dongsheng He ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Design And Synthesis ◽  
Targeted Drug

scholarly journals Recent trends on hydrogel based drug delivery systems for infectious diseases

2016 ◽  
Vol 4 (11) ◽  
pp. 1535-1553 ◽  
Author(s):  
Arti Vashist ◽  
Ajeet Kaushik ◽  
Atul Vashist ◽  
Rahul Dev Jayant ◽  
Asahi Tomitaka ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Infectious Diseases ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Therapeutic Agents ◽  
Delivery Systems ◽  
Recent Trends ◽  
Targeted Drug ◽  
Targeted Drug Delivery Systems

Hydrogel based drug delivery systems owe excellent potential as targeted drug delivery systems for the delivery of therapeutic agents and diagnostics for major infectious diseases.

scholarly journals Micro/Nanorobot: A Promising Targeted Drug Delivery System

Pharmaceutics ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 665 ◽  
Author(s):  
Mengyi Hu ◽  
Xuemei Ge ◽  
Xuan Chen ◽  
Wenwei Mao ◽  
Xiuping Qian ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Electric Fields ◽  
Targeted Drug Delivery ◽  
Disease Diagnosis ◽  
Research Field ◽  
Traditional Drug ◽  
Targeted Drug ◽  
Autonomous Movement

Micro/nanorobot, as a research field, has attracted interest in recent years. It has great potential in medical treatment, as it can be applied in targeted drug delivery, surgical operation, disease diagnosis, etc. Differently from traditional drug delivery, which relies on blood circulation to reach the target, the designed micro/nanorobots can move autonomously, which makes it possible to deliver drugs to the hard-to-reach areas. Micro/nanorobots were driven by exogenous power (magnetic fields, light energy, acoustic fields, electric fields, etc.) or endogenous power (chemical reaction energy). Cell-based micro/nanorobots and DNA origami without autonomous movement ability were also introduced in this article. Although micro/nanorobots have excellent prospects, the current research is mainly based on in vitro experiments; in vivo research is still in its infancy. Further biological experiments are required to verify in vivo drug delivery effects of micro/nanorobots. This paper mainly discusses the research status, challenges, and future development of micro/nanorobots.

Design and synthesis of aptamer AS1411-conjugated EG@TiO2@Fe2O3 nanoparticles as a drug delivery platform for tumor-targeted therapy

2020 ◽  
Vol 44 (37) ◽  
pp. 15871-15886 ◽  
Author(s):  
Nahid Mansouri ◽  
Razieh Jalal ◽  
Batool Akhlaghinia ◽  
Khalil Abnous ◽  
Roya Jahanshahi
Keyword(s):  
Drug Delivery ◽  
Targeted Therapy ◽  
Sustained Release ◽  
Targeted Drug Delivery ◽  
Fe2o3 Nanoparticles ◽  
Ph Responsive ◽  
Release System ◽  
Design And Synthesis ◽  
Delivery Platform ◽  
Targeted Drug

AS1411@GMBS@EG@TiO2@Fe2O3 nanoparticle is an effective and safe pH-responsive sustained release system for targeted drug delivery into nucleolin-positive cells.

Novel DNA Aptamers Against CCL21 Protein: Characterization and Biomedical Applications for Targeted Drug Delivery to T Cell-Rich Zones

2018 ◽  
Vol 28 (4) ◽  
pp. 242-251 ◽  
Author(s):  
Louis Chonco ◽  
Gerónimo Fernández ◽  
Rahul Kalhapure ◽  
María J. Hernáiz ◽  
Cecilia García-Oliva ◽  
...  
Keyword(s):  
Drug Delivery ◽  
T Cell ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Protein Characterization ◽  
Dna Aptamers ◽  
Targeted Drug

scholarly journals Advances in the use of nanocarriers for cancer diagnosis and treatment

2016 ◽  
Vol 14 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Débora Braga Vieira ◽  
Lionel Fernel Gamarra
Keyword(s):  
Drug Delivery ◽  
Cancer Diagnosis ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Surface Engineering ◽  
Diagnosis And Treatment ◽  
Pharmacological Properties ◽  
Clinical Use ◽  
Targeted Drug ◽  
Future Work

ABSTRACT The use of nanocarriers as drug delivery systems for therapeutic or imaging agents can improve the pharmacological properties of commonly used compounds in cancer diagnosis and treatment. Advances in the surface engineering of nanoparticles to accommodate targeting ligands turned nanocarriers attractive candidates for future work involving targeted drug delivery. Although not targeted, several nanocarriers have been approved for clinical use and they are currently used to treat and/or diagnosis various types of cancers. Furthermore, there are several formulations, which are now in various stages of clinical trials. This review examined some approved formulations and discussed the advantages of using nanocarriers in cancer therapy.

scholarly journals Advances in Magnetic Nanoparticles Engineering for Biomedical Applications—A Review

2021 ◽  
Vol 8 (10) ◽  
pp. 134
Author(s):  
Abdulkader Baki ◽  
Frank Wiekhorst ◽  
Regina Bleul
Keyword(s):  
Drug Delivery ◽  
Iron Oxide ◽  
Diagnostic Imaging ◽  
Iron Oxide Nanoparticles ◽  
Magnetic Fluid ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Magnetic Fluid Hyperthermia ◽  
Targeted Drug

Magnetic iron oxide nanoparticles (MNPs) have been developed and applied for a broad range of biomedical applications, such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery, gene therapy and tissue repair. As one key element, reproducible synthesis routes of MNPs are capable of controlling and adjusting structure, size, shape and magnetic properties are mandatory. In this review, we discuss advanced methods for engineering and utilizing MNPs, such as continuous synthesis approaches using microtechnologies and the biosynthesis of magnetosomes, biotechnological synthesized iron oxide nanoparticles from bacteria. We compare the technologies and resulting MNPs with conventional synthetic routes. Prominent biomedical applications of the MNPs such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery and magnetic actuation in micro/nanorobots will be presented.

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