scholarly journals Synthesis of Azidothymidine-Bound Sulfated Alkyl Oligosaccharides and Their Inhibitory Effects on AIDS Virus Infection in vitro

1998 ◽  
Vol 30 (3) ◽  
pp. 243-248 ◽  
Author(s):  
Ying Gao ◽  
Kaname Katsuraya ◽  
Yutaro Kaneko ◽  
Toru Mimura ◽  
Hideki Nakashima ◽  
...  
1990 ◽  
Vol 23 (16) ◽  
pp. 3717-3722 ◽  
Author(s):  
Takashi Yoshida ◽  
Kenichi Hatanaka ◽  
Toshiyuki Uryu ◽  
Yutaro Kaneko ◽  
Eiichiro Suzuki ◽  
...  

2015 ◽  
Vol 46 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Siriwan Charyasriwong ◽  
Ken Watanabe ◽  
Ratika Rahmasari ◽  
Ayaka Matsunaga ◽  
Takahiro Haruyama ◽  
...  

1994 ◽  
Vol 27 (22) ◽  
pp. 6272-6276 ◽  
Author(s):  
Takashi Yoshida ◽  
Yuichi Yasuda ◽  
Toshiyuki Uryu ◽  
Hideki Nakashima ◽  
Naoki Yamamoto ◽  
...  

2004 ◽  
Vol 27 (6) ◽  
pp. 825-830 ◽  
Author(s):  
Kazuya I. P. J. Hidari ◽  
Eisaku Tsujii ◽  
Jun Hiroi ◽  
Eriko Mano ◽  
Akihiko Miyatake ◽  
...  

ChemInform ◽  
2010 ◽  
Vol 25 (44) ◽  
pp. no-no
Author(s):  
K. KATSURAYA ◽  
N. IKUSHIMA ◽  
N. TAKAHASHI ◽  
T. SHOJI ◽  
H. NAKASHIMA ◽  
...  

1995 ◽  
Vol 28 (20) ◽  
pp. 6697-6700 ◽  
Author(s):  
Kaname Katsuraya ◽  
Takashi Shibuya ◽  
Kazuhiko Inazawa ◽  
Hideki Nakashima ◽  
Naoki Yamamoto ◽  
...  

1994 ◽  
Vol 260 (1) ◽  
pp. 51-61 ◽  
Author(s):  
Kaname Katsuraya ◽  
Naoya Ikushima ◽  
Nahoko Takahashi ◽  
Tadao Shoji ◽  
Hideki Nakashima ◽  
...  

Author(s):  
Pınar Ercan ◽  
Sedef Nehir El

Abstract. The goals of this study were to determine and evaluate the bioaccessibility of total anthocyanin and procyanidin in apple (Amasya, Malus communis), red grape (Papazkarası, Vitis vinifera) and cinnamon (Cassia, Cinnamomum) using an in vitro static digestion system based on human gastrointestinal physiologically relevant conditions. Also, in vitro inhibitory effects of these foods on lipid (lipase) and carbohydrate digestive enzymes (α-amylase and α-glucosidase) were performed with before and after digested samples using acarbose and methylumbelliferyl oleate (4MUO) as the positive control. While the highest total anthocyanin content was found in red grape (164 ± 2.51 mg/100 g), the highest procyanidin content was found in cinnamon (6432 ± 177.31 mg/100 g) (p < 0.05). The anthocyanin bioaccessibilities were found as 10.2 ± 1%, 8.23 ± 0.64%, and 8.73 ± 0.70% in apple, red grape, and cinnamon, respectively. The procyanidin bioaccessibilities of apple, red grape, and cinnamon were found as 17.57 ± 0.71%, 14.08 ± 0.74% and 18.75 ± 1.49%, respectively. The analyzed apple, red grape and cinnamon showed the inhibitory activity against α-glucosidase (IC50 544 ± 21.94, 445 ± 15.67, 1592 ± 17.58 μg/mL, respectively), α-amylase (IC50 38.4 ± 7.26, 56.1 ± 3.60, 3.54 ± 0.86 μg/mL, respectively), and lipase (IC50 52.7 ± 2.05, 581 ± 54.14, 49.6 ± 2.72 μg/mL), respectively. According to our results apple, red grape and cinnamon have potential to inhibit of lipase, α-amylase and α-glucosidase digestive enzymes.


Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
YC Oh ◽  
YH Jeong ◽  
WK Cho ◽  
SJ Lee ◽  
JY Ma

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