scholarly journals Analysis of Blood Flow in a Third Ventricular Ependymoma and an Olfactory Bulb Meningioma by using Perfusion Computed Tomography

2008 ◽  
Vol 70 (9) ◽  
pp. 981-983 ◽  
Author(s):  
Miori KISHIMOTO ◽  
Kazutaka YAMADA ◽  
Joon-Soo SEOK ◽  
Junichiro SHIMIZU ◽  
Yoshiyasu KOBAYASHI ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Olfactory Bulb ◽  
Perfusion Computed Tomography

scholarly journals Hepatic blood flow by perfusion computed tomography as an imaging biomarker for patients with gastric cancer

2019 ◽  
Author(s):  
Kiyohiko Shuto ◽  
Mikito Mori ◽  
Chihiro Kosugi ◽  
Kazuo Narushima ◽  
Satoko Nakabayashi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Computed Tomography ◽  
Blood Flow ◽  
Hepatic Blood Flow ◽  
Imaging Biomarker ◽  
Perfusion Computed Tomography

A comparative analysis of cerebral asymmetry according to data from perfusion computed tomography in infarctions of the cerebral hemispheres and dyscirculatory encephalopathy

2015 ◽  
Vol 9 (4) ◽  
pp. 0-0
Author(s):  
Сеинова ◽  
L. Seinova
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Comparative Analysis ◽  
Brain Ischemia ◽  
Hemispheric Asymmetry ◽  
Cerebral Hemispheres ◽  
Perfusion Computed Tomography ◽  
Dyscirculatory Encephalopathy ◽  
Chronic Brain Ischemia ◽  
The Brain

Currently a problem of timely diagnostics and treatment of disorders of cerebral circulation is one of the most important for medicine, as strokes and chronic brain ischemia occupy a significant place among the diseases leading to mortality and disability of population. Computed tomography is one of the leading diagnostics of cerebro-vascular disorders. Today, the diagnostic capabilities of perfusion computed tomography, especially in the field of subtle changes in perfusion in infected and in the contralateral hemispheres of the brain are poorly understood and aren’t used in full. The relevance and scientific novelty of this research is not in doubt. Based on the data of 87 patients with ischemic infarction of the cerebral hemispheres of the brain and vascular encephalopathy, a comparative analysis of blood flow in the affected and contralateral hemispheres, was carried out. The degree of asymmetry of blood flow depending on the phase of development of ischemic stroke and chronic brain ischemia was evaluated. The studies have shown that the relative indicator of inter-hemispheric asymmetry is reduced in the course of development of cerebral infarction, reaching minimum values of dyscirculatory encephalopathy. The author substantiates the practical use of the proposed indicator of inter-hemispheric asymmetry in the evaluation of the degree of chronic ischemic disturbances of cerebral blood flow.

scholarly journals A trial of the use of perfusion computed tomography of the brain in combination with transcranial Doppler ultrasonography of blood vessels in patients with acute cerebrovascular accident

2020 ◽  
Vol 101 (1) ◽  
pp. 124-131
Author(s):  
K G Valeeva ◽  
S K Perminova ◽  
A Ya Nazipova ◽  
S V Kurochkin ◽  
A A Yakupova
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Transcranial Doppler ◽  
Cerebrovascular Accident ◽  
Doppler Ultrasonography ◽  
Transcranial Doppler Ultrasonography ◽  
Perfusion Computed Tomography ◽  
Acute Cerebrovascular Accident ◽  
Vascular Beds ◽  
The Brain

Aim. Assessment of cerebral blood flow in various vascular beds in patients with an acute cerebrovascular accident in the acute period by perfusion computed tomography in combination with transcranial Doppler ultrasonography of cerebral vessels. Methods. Data was analyzed from perfusion computed tomography of the brain and transcranial Doppler ultrasonography in 35 patients with an acute cerebrovascular accident, based at the vascular centre of the City Clinical Hospital No. 7 of Kazan. The study included 18 (51.4%) women and 17 (48.6%) men who had arrived in the first hours after a vascular accident. When analyzing the stroke subtype, atherothrombotic subtype was determined in 27 (77.1%) patients, cardioembolic subtype in 5 (14.3%) patients, and 3 (8.6%) patients had had a transient ischemic attack. Results. Perfusion computed tomography is a method that allowed evaluation of the structure of the brain, and blood supply to the anterior cerebral (in 2.9% of the studied patients), middle cerebral (in 62.9% of the studied patients), posterior cerebral (in 11.4% of the studied patients) and vertebral (in 14.2% of the studied patients) arteries of patients with a stroke. The method revealed a zone of critical perfusion (ischemic penumbra) by quantitatively processing perfusion indicators in the anterior cerebral blood flow system (decrease in rate and increase in average volume of cerebral blood flow and average transit time) and in the posterior cerebral circulation system (decrease in blood flow and prolongation of transit time) in the bed of the right vertebral artery). The method also aided the construction of perfusion maps. Transcranial Doppler ultrasonography of cerebral vessels revealed breaches in the cerebral circulation: a decrease in the linear velocity of blood flow in the right middle cerebral arterial bed and in the posterior circulatory system of blood flow in the brain, and an increase in the pulsatility index in all the studied vascular beds. Conclusion. Perfusion computed tomography of the brain in combination with transcranial Doppler ultrasonography is applicable to patients with stroke in various vascular beds, followed by determination of indications for thrombolytic therapy and thrombectomy.

Reproducibility of dynamic computed tomography brain perfusion measurements in patients with significant carotid artery stenosis

2009 ◽  
Vol 50 (2) ◽  
pp. 226-232 ◽  
Author(s):  
Z. Serafin ◽  
M. Kotarski ◽  
M. Karolkiewicz ◽  
R. Mindykowski ◽  
W. Lasek ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Cerebral Blood Volume ◽  
Artery Stenosis ◽  
Intraobserver Variability ◽  
Maximum Slope ◽  
Perfusion Computed Tomography ◽  
Significant Difference

Background: Perfusion computed tomography (PCT) determination is a minimally invasive and widely available technique for brain blood flow assessment, but its application may be restricted by large variation of results. Purpose: To determine the intraobserver, interobserver, and interexamination variability of brain PCT absolute measurements in patients with significant carotid artery stenosis (CAS), and to evaluate the effect of the use of relative perfusion values on PCT reproducibility. Material and Methods: PCT imaging was completed in 61 patients before endarterectomy, and in 38 of these within 4 weeks after treatment. Cerebral blood flow (CBF), cerebral blood volume (CBV), time to peak (TTP), and peak enhancement intensity (PEI) were calculated with the maximum slope method. Interexamination variability was evaluated based on perfusion of hemisphere contralateral to the treated CAS, from repeated examinations. Interobserver and intraobserver variability were established for the untreated side, based on pretreatment examination. Results: Interobserver and intraobserver variability were highest for CBF measurement (28.8% and 32.5%, respectively), and interexamination variability was the highest for CBV (24.1%). Intraobserver and interobserver variability were higher for absolute perfusion values compared with their respective ratios for CBF and TTP. The only statistically significant difference between perfusion values measured by two observers was for CBF (mean 78.3 vs. 67.5 ml/100 g/min). The interexamination variability of TTP (12.1%) was significantly lower than the variability of other absolute perfusion measures, and the interexamination variability of ratios was significantly lower than absolute values for all the parameters. Conclusion: In longitudinal studies of patients with chronic cerebral ischemia, PCT ratios and either TTP or CBV are more suitable measures than absolute CBF values, because of their considerably lower inter- and intraobserver variability. Differences in CBF between two examinations as high as 30% may be considered as significant in such patients.

Integration Between Computed Tomography and Nuclear Medicine for Non-invasive Assessment of Coronary Anatomy and Myocardial Perfusion

2009 ◽  
Vol 5 (2) ◽  
pp. 15
Author(s):  
Wanda Acampa ◽  
Mario Petretta ◽  
Carmela Nappi ◽  
Alberto Cuocolo ◽  
◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Heart Disease ◽  
Blood Flow ◽  
Heart Disease ◽  
Myocardial Perfusion ◽  
Myocardial Blood Flow ◽  
Imaging Techniques ◽  
Emission Computed Tomography ◽  
Coronary Anatomy ◽  
Non Invasive

Many non-invasive imaging techniques are available for the evaluation of patients with known or suspected coronary heart disease. Among these, computed-tomography-based techniques allow the quantification of coronary atherosclerotic calcium and non-invasive imaging of coronary arteries, whereas nuclear cardiology is the most widely used non-invasive approach for the assessment of myocardial perfusion. The available single-photon-emission computed tomography flow agents are characterised by a cardiac uptake proportional to myocardial blood flow. In addition, different positron emission tomography tracers may be used for the quantitative measurement of myocardial blood flow and coronary flow reserve. Extensive research is being performed in the development of non-invasive coronary angiography and myocardial perfusion imaging using cardiac magnetic resonance. Finally, new multimodality imaging systems have recently been developed bringing together anatomical and functional information. This article provides a description of the available non-invasive imaging techniques in the assessment of coronary anatomy and myocardial perfusion in patients with known or suspected coronary heart disease.

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